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1566 articles

October 202624

Clinical ResearchInfectious Diseases

Pharmacokinetics, Immunogenicity, and Safety of a Modified YTE Antibody in Healthy Adults.

This Phase I randomized controlled trial evaluated the pharmacokinetics, immunogenicity, and safety of REGN17092, a modified YTE antibody targeting SARS-CoV-2, in 40 healthy adults.

Clin Pharmacol Drug DevOct 1, 2026Read summary
Case ReportInfectious Diseases

Buruli Ulcer Acquired From Ringtail Possum Rescue.

A patient presented with a Buruli ulcer, which was likely acquired from a scratch by a ringtail possum during a rescue attempt. This case highlights a newly recognized transmission route for Buruli ulcer.

Med J AustOct 1, 2026Read case
Clinical ResearchGastroenterology

Enhanced recovery after colorectal surgery in patients with inflammatory bowel disease to reduce hospital length of stay: A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the impact of enhanced recovery after surgery (ERAS) protocols on adult patients with inflammatory bowel disease (IBD).

Colorectal DisOct 1, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Systematic Review and Meta-analysis of Group B Streptococcus Rectovaginal Colonization Rates and Serotype Distribution among Pregnant Women, Asia-Pacific Region, 2014-2025.

This systematic review and meta-analysis examined group B Streptococcus (GBS) rectovaginal colonization rates among 978,150 pregnant women in the Asia-Pacific region.

Emerg Infect DisOct 1, 2026Read summary
Clinical ResearchInfectious Diseases

Meta-analysis of Maternal and Fetal Outcomes of Crimean-Congo Hemorrhagic Fever during Pregnancy.

This meta-analysis examined the maternal and fetal outcomes of Crimean-Congo hemorrhagic fever (CCHF) in 55 pregnancies. The study found a maternal mortality rate of 28.8% and a fetal loss rate of 57.4%.

Emerg Infect DisOct 1, 2026Read summary
Clinical ResearchInfectious Diseases

Meta-analysis of Asymptomatic Monkeypox Virus Prevalence in Nonendemic Regions, 2022-2024.

This meta-analysis examined the prevalence of asymptomatic monkeypox virus (MPXV) detections in nonendemic regions from May 2022 to September 2024.

Emerg Infect DisOct 1, 2026Read summary
Clinical ResearchPediatrics

A Systematic Review and Meta-Analysis of the Prevention and Management of Pediatric Urinary Tract Infection and Suspected Urinary Tract Infection: Technical Report.

This systematic review and meta-analysis evaluated management strategies for pediatric urinary tract infections (UTIs) in children without known anatomic anomalies, including antibiotic duration and route, and the use…

PediatricsOct 1, 2026Read summary
Clinical ResearchPediatrics

A Systematic Review and Meta-Analysis of the Role of Ultrasonography for the Diagnosis of Vesicoureteral Reflux in Pediatric Patients Following Urinary Tract Infections: Technical Report.

This systematic review and meta-analysis evaluated the diagnostic accuracy of renal and bladder ultrasonography (RBUS) for detecting vesicoureteral reflux (VUR) in pediatric patients post-urinary tract infection (UTI).

PediatricsOct 1, 2026Read summary
Clinical ResearchPediatrics

Pediatric Literacy Promotion for Latino Families by Texts and Referrals: A 3-Arm RCT.

This randomized controlled trial evaluated two strategies to enhance literacy promotion among 630 Latino caregiver-infant dyads.

PediatricsOct 1, 2026Read summary
Clinical ResearchPediatrics

Behavioral Interventions in Pediatric Type 1 Diabetes Management: An Updated Meta-Analysis.

This updated meta-analysis evaluated the impact of behavioral interventions on hemoglobin A1C (HbA1C) in youths with type 1 diabetes (T1D) across 46 randomized controlled trials.

PediatricsOct 1, 2026Read summary
Case ReportPediatrics

Hereditary TTP and Hemolytic Anemia in Newborns.

This case report discusses three siblings diagnosed with hereditary thrombotic thrombocytopenic purpura (hTTP) due to ADAMTS13 deficiency, presenting with severe jaundice at birth.

PediatricsOct 1, 2026Read case
Case ReportPediatrics

Black Pleural Effusion as a Rare Presentation of Serotype 3 Pneumococcal Empyema.

A previously healthy 6-year-old boy presented with severe pneumonia, leading to the discovery of a black pleural effusion during thoracentesis.

PediatricsOct 1, 2026Read case
Clinical ResearchPediatrics

Spread and Sustainability of an Antimicrobial Stewardship Initiative Within a Pediatric Network.

This randomized controlled trial evaluated the sustainability of an antimicrobial stewardship initiative in a pediatric network, focusing on prescribing practices for skin and soft tissue infections (SSTI).

PediatricsOct 1, 2026Read summary
Case ReportPediatrics

A 6-Year-Old With Becker Muscular Dystrophy and Catatonia.

A 6-year-old boy presented with acute behavioral changes suggestive of catatonia, including altered speech and awareness. He was found to have previously undiagnosed Becker muscular dystrophy.

PediatricsOct 1, 2026Read case
Clinical ResearchOncology (Medical)

Immersive Virtual Reality and Anxiety, Nausea, and Vomiting in Children With Cancer: An RCT.

This randomized controlled trial evaluated the impact of immersive virtual reality (IVR) on anxiety, anticipatory nausea, and chemotherapy-induced nausea and vomiting (CINV) in pediatric cancer patients aged 6-12…

PediatricsOct 1, 2026Read summary
Case ReportPediatrics

Continuous Renal Replacement Therapy for Cytokine Storm in Diabetic Kawasaki Shock Syndrome.

A 3-year, 10-month-old boy with poorly controlled type 1 diabetes and autoimmune thyroiditis presented with Kawasaki disease shock syndrome and diabetic ketoacidosis.

PediatricsOct 1, 2026Read case
Clinical ResearchPediatrics

Measurement Properties of Delirium Tools in Pediatric Intensive Care: A Systematic Review.

This systematic review evaluated the measurement properties of pediatric delirium tools in intensive care, analyzing 41 studies.

PediatricsOct 1, 2026Read summary
Clinical ResearchPulmonology

Three versus six weeks of corticosteroids for mild immune-related pneumonitis: a randomized trial.

This randomized controlled trial evaluated the efficacy of a 3-week versus a 6-week corticosteroid taper in patients with mild immune-related pneumonitis.

Am J Respir Crit Care MedOct 1, 2026Read summary
Clinical ResearchInfectious Diseases

Association of white blood cell count with treatment response to cefepime versus piperacillin-tazobactam.

This randomized controlled trial analyzed the impact of white blood cell (WBC) count on the effectiveness of cefepime versus piperacillin-tazobactam in treating sepsis.

Am J Respir Crit Care MedOct 1, 2026Read summary
Clinical ResearchPulmonology

Pulmonary specialist health coach consultation model: a randomized controlled trial.

This randomized controlled trial evaluated a pulmonary specialist health coach consultation model for low-income patients with asthma and/or COPD.

Ann Am Thorac SocOct 1, 2026Read summary
Clinical ResearchGastroenterology

The missing evidence: Stricturing Crohn's disease in clinical trials, a systematic review.

This systematic review assessed the efficacy of biologic and small-molecule therapies in stricturing Crohn's disease (CD) among adults.

Inflamm Bowel DisOct 1, 2026Read summary
Clinical ResearchGastroenterology

Advanced therapies for extraintestinal manifestations of IBD: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the efficacy of advanced therapies (ATs) for extraintestinal manifestations (EIMs) in patients with inflammatory bowel diseases (IBD).

Inflamm Bowel DisOct 1, 2026Read summary
Clinical ResearchPediatricsOpen access

Early-life liquefied petroleum gas cooking intervention and lung function in Guatemalan children: a randomized clinical trial.

This randomized clinical trial assessed the impact of an early-life liquefied petroleum gas cooking intervention on lung function in Guatemalan children.

Ann Am Thorac SocOct 1, 2026Read summary
Clinical ResearchPsychiatry

Quetiapine modestly improves sleep and breathing but impairs next-day performance in people with obstructive sleep apnea and difficulty maintaining sleep: a randomized controlled trial.

This randomized controlled trial evaluated the effects of 50 mg quetiapine versus placebo in 15 individuals with obstructive sleep apnea (OSA) and difficulty maintaining sleep.

Ann Am Thorac SocOct 1, 2026Read summary

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