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55 articles
October 202624
Fertility Treatment and Risk of Melanoma: A Certainty-Rated Systematic Review and Meta-Analysis of 3,733,499 Women.
This certainty-rated systematic review and random-effects meta-analysis examined observational evidence on fertility treatment and incident melanoma in women.
Combination therapy of carbon dioxide laser with topical halometason cream and 308 nm excimer laser for the treatment of vitiligo: an optimized combined treatment protocol.
This randomized controlled trial evaluated fractional CO₂ laser plus topical halometasone cream and 308-nm excimer lamp therapy for refractory non-segmental vitiligo, compared with excimer therapy, a topical calcineurin…
Fractional CO₂ laser combined with intradermal and topical platelet-rich plasma for hypertrophic scars: a randomized controlled trial.
This prospective, randomized, assessor-blinded trial compared fractional CO₂ laser plus intradermal and topical platelet-rich plasma (PRP) with laser plus saline in 120 patients with hypertrophic scars.
Balancing safety and efficacy in photodynamic therapy for facial port-wine stains in children aged 2-7 years: a prospective controlled study of light-intensity optimization.
This open-label, prospective controlled study compared two light intensities for hemoporfin-mediated photodynamic therapy in children aged 2–7 years with facial port-wine stains.
Thulium laser-assisted delivery of growth factors for treating androgenetic alopecia - a randomized, controlled, clinical study.
This pilot randomized controlled study evaluated non-ablative fractional laser (NAFL)-assisted delivery of a biomimetic growth factor serum, with or without red light therapy, in patients with androgenetic alopecia.
5-Aminolevulinic acid-based photodynamic therapy used as a long-term management approach for refractory lichen sclerosus.
A 37-year-old man with more than 10 years of genital lichen sclerosus had recurrence after surgical resection, which left permanent anatomical deformity.
Blood, ink, and flies: A case report on the house fly (Musca domestica) feeding on active tattooing wounds.
During a tattoo session, a healthy 32-year-old man in Germany experienced repeated landing and feeding attempts by house flies on freshly wounded skin of his right lower leg.
Inherited epidermal differentiation disorders (EDD) in pediatric patients from a single Italian referral Center.
A retrospective review at an Italian referral center described three children with congenital, clinically heterogeneous inherited epidermal differentiation disorders.
Long-term efficacy of lebrikizumab in treating head, neck and face involvement in patients with moderate-to-severe atopic dermatitis.
This post hoc analysis of phase III trials assessed head, neck, and face (HNF) outcomes with lebrikizumab in adolescents and adults with moderate-to-severe atopic dermatitis.
Metal Hypersensitivity Reactions Following Spinal Implants: A Systematic Review.
This systematic review examined clinical presentation, diagnostic approaches, and outcomes of metal hypersensitivity after spinal implant surgery in adults.
Isolated Bilateral Periocular Lupus Miliaris Disseminatus Faciei: A Clinicopathological Mimicker of Granulomatosis With Polyangiitis.
A healthy young adult man presented with symmetrical papules confined to both periocular regions. Eyelid biopsy showed suppurative necrotizing granulomatous inflammation, prompting concern for granulomatosis with…
Efficacy and safety of subcutaneous efgartigimod with prednisone in moderate-to-severe pemphigus (ADDRESS): a global, phase III, randomised controlled, double-blind trial.
ADDRESS was a global, phase III, multicentre, randomised, double-blind, placebo-controlled trial of adults with newly diagnosed or relapsing moderate-to-severe pemphigus.
Oral mucous membrane pemphigoid as a window to systemic autoimmunity: two cases associated with rheumatoid arthritis and Sjögren's disease.
Two women presented with oral mucous membrane pemphigoid (MMP) in the setting of systemic autoimmunity. A 68-year-old woman with longstanding rheumatoid arthritis had recurrent oral ulcerations confirmed as MMP on…
Approach to the patient with APS-1/APECED.
This article presents five cases of autoimmune polyendocrine syndrome type 1 (APS-1/APECED), a disorder caused by impaired immune tolerance and typically associated with biallelic AIRE variants.
Tranilast/roxithromycin with topical tacrolimus in refractory atopic facial eczema: Case report.
A 30-year-old man with atopic dermatitis had facial eczema and severe itching that persisted despite conventional treatment, including oral betamethasone.
Hyaluronic acid-based skin booster with glutathione combined with 1064-nm Nd:YAG laser and oral tranexamic acid for melasma: A prospective comparative study.
This randomized comparative study evaluated whether intradermal hyaluronic acid-based glutathione (HA-GSH) improves outcomes when added to low-fluence 1064-nm Q-switched Nd:YAG laser and oral tranexamic acid in Chinese…
A Prospective, Multicenter, Evaluator-Blind, Randomized, Comparator-Controlled Study of Belotero Intense (+), a Hyaluronic Acid Filler With Lidocaine, for Lip Augmentation.
This multicenter, evaluator-blind randomized comparator-controlled equivalence trial assessed Belotero Intense with lidocaine (BIL) for lip augmentation in patients with lip volume deficits, comparing it with Restylane…
Focal Epithelial Hyperplasia in a Somali Child: A Case Report and Review of Management with Topical Imiquimod.
An 8-year-old Somali girl had a 3.5-year history of asymptomatic, progressively increasing oral lesions. Examination showed multiple soft, flat-topped verrucous papules on the lower labial, buccal and lingual mucosa and…
The Use of Cannabidiol in Cutaneous Wound Healing: A Systematic Review.
This qualitative systematic review assessed cannabidiol (CBD) for cutaneous wound healing, including in vivo studies and clinical trials identified through searches of seven databases. Six studies were included.
Exploring the landscape of flagellate erythema as a rare cutaneous symptom of idiopathic inflammatory myopathy: a case series-based review.
Two patients with idiopathic inflammatory myopathy developed zebra-like flagellate erythema: one had immune-mediated necrotising myopathy and the other anti-Mi-2-positive cancer-associated myositis.
Targeting an IL-17/IL-36 pathogenic hub in hidradenitis suppurativa with a bispecific antibody.
This phase I/II proof-of-concept clinical trial evaluated HB0043, a bispecific antibody targeting IL-17A and IL-36R, in patients with severe, tunnel-dominant Hurley Stage III hidradenitis suppurativa.
Fecal microbiota transplantation for the treatment of neurogenic rosacea: protocol of a randomized, blinded, placebo-controlled explorer study.
This publication describes the protocol for a single-center, randomized, double-blind, placebo-controlled exploratory trial of fecal microbiota transplantation (FMT) in patients with neurogenic rosacea, a phenotype…
Multiple-Staged Versus Single-Stage Surgical Excision for the Reconstruction of Congenital Melanocytic Nevi: A Meta-Analysis of Efficacy and Safety.
This meta-analysis compared multiple-staged with single-stage excision and reconstruction for congenital melanocytic nevi (CMN). It pooled seven retrospective cohort or clinical controlled studies involving 578 patients.
Clinical translation of polymeric microneedles for bioactive nanovesicle delivery in hypertrophic scar remodeling.
This prospective, single-center, open-label, single-arm study evaluated a 12-week protocol combining microplasma radiofrequency, poly(L-lactic acid) microneedles, and topical milk-derived bioactive nanovesicles in 26…
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