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1687 articles
October 202624
Predictors of immunological non-response despite virological suppression in people living with HIV on antiretroviral therapy: A systematic review and meta-analysis.
This systematic review and meta-analysis examined clinical, demographic and molecular predictors of inadequate CD4+ T-cell recovery despite viral suppression on antiretroviral therapy in people living with HIV.
Effectiveness of a self-management intervention on clinical outcomes among patients with type 2 diabetes at high risk for Diabetic Kidney Disease: A Randomised Controlled Trial.
This prospective, two-arm randomised controlled trial at a tertiary hospital in China evaluated a structured self-management programme in 134 adults with type 2 diabetes classified as at high risk of diabetic kidney…
Menstrual health challenges and associated barriers among tribal adolescent girls in India: A systematic review.
This systematic review synthesised quantitative, qualitative and mixed-methods research on menstrual health among tribal adolescent girls in India.
Hodgkin Lymphoma With Sarcoid-Like Reaction: Importance of Clinicopathological Correlation in Granulomatous Lymphadenopathy.
A 63-year-old man with systemic lymphadenopathy had a cervical lymph node biopsy showing epithelioid granulomas but no identifiable neoplastic cells, prompting an initial suspicion of sarcoidosis.
Early-onset autosomal dominant distal renal tubular acidosis caused by a de novo SLC4A1 R589C variant with growth failure and rickets.
A Japanese boy had marked growth failure from 6 months of age and was diagnosed with autosomal dominant distal renal tubular acidosis at 27 months.
A case of immunofluorescence-negative light chain deposition disease diagnosed by mass spectrometry.
A 53-year-old man with kidney dysfunction and edema had nodular glomerular lesions on biopsy, but immunofluorescence did not show immunoglobulin or light-chain deposits.
Postoperative acute kidney injury associated with cast nephropathy and marked renal interstitial plasma cell infiltration in multiple myeloma: a case report.
An 84-year-old man with smoldering multiple myeloma developed severe acute kidney injury after lumbar fixation for a burst fracture.
Delayed eculizumab therapy guided by markedly elevated soluble C5b-9 in a child with dialysis-requiring acute poststreptococcal glomerulonephritis: a case report.
A 9-year-old girl developed gross haematuria, oliguria and stage 3 acute kidney injury after an illness with vomiting and abdominal pain.
Next-generation pharmacological strategies for Parkinson's disease: a systematic literature review of symptom management and disease modification.
This PRISMA 2020 systematic literature review assessed pharmacological and emerging therapeutic strategies for symptom management and disease modification in Parkinson disease.
Resilience interventions for stress-related health outcomes in patients with cancer: Findings from a systematic review of randomized controlled trials.
This systematic review synthesized randomized controlled trials of resilience interventions for stress-related health outcomes in patients with cancer.
Anatomical variation in the cervical branch of the facial nerve: a systematic review.
There is a paucity of literature on the anatomical variations of the cervical branch of the facial nerve (CBFN). Poor awareness of its anatomy and variations risks intraoperative damage, misdiagnosis of facial nerve…
Laparoscopic and robotic management of symptomatic calyceal diverticula: a systematic review on behalf of YAU and EAU endourology.
This systematic review assessed laparoscopic and robot-assisted management of symptomatic calyceal diverticula. Nine studies were included in a qualitative synthesis.
Dynamics and functional heterogeneity of FOXP3+ regulatory T cells in Trypanosoma cruzi infection: a systematic review.
This systematic review synthesised 27 studies of FOXP3+ regulatory T-cell (Treg) phenotype and function in human and experimental Trypanosoma cruzi infection: 9 human studies and 18 murine studies.
A case of renal hypouricemia type 1 associated with compound heterozygous URAT1/SLC22A12 variants A209V and F379L: clinical evidence for their pathogenic significance.
A 69-year-old woman was evaluated for renal dysfunction and hypouricemia. Testing showed serum uric acid of 0.7 mg/dL and a fractional urate clearance (Cua/Ccr) of 60.5%, alongside CKD stage G3b and a renal stone.
Continuous intrathecal therapy for refractory cancer pain: A systematic review and meta-analysis focusing on partially implanted devices.
This systematic review and meta-analysis assessed partially implanted intrathecal devices (PIDs) for adults with refractory cancer-related pain, comparing them with conventional medical management and, in comparative…
Blood pressure targets in adults with hypertension.
This publication is a protocol for a Cochrane intervention review, not a report of completed results. It sets out to assess lower blood pressure targets (≤ 135/85 mmHg) versus standard targets (≤ 140 to 160/90 to 100…
Home visits following hospital discharge for families with preterm and low-birthweight infants.
This Cochrane systematic review and meta-analysis assessed randomised trials of home visits after discharge for families of preterm or low-birthweight infants.
Extracting the Unexpected: A 35-mm Curved Nail as an Intraocular Foreign Body.
A 31-year-old man presented with left-eye pain and severe vision loss seven days after penetrating injury from a metallic object.
Effect of injectable platelet rich fibrin augmented with vitamin c compared to injectable platelet rich fibrin alone on healing of necrotic mature single rooted teeth with chronic periapical periodontitis following regenerative endodontic therapy (a randomized controlled trial).
This randomized controlled trial compared injectable platelet-rich fibrin (i-PRF) with and without vitamin C during regenerative endodontic treatment in 28 healthy patients with necrotic mature single-rooted teeth and…
Comparative perioperative outcomes of Hugo™ RAS versus laparoscopic and Da Vinci platforms for partial nephrectomy: a systematic review and meta-analysis.
This systematic review and meta-analysis compared Hugo™ RAS with da Vinci-assisted and laparoscopic partial nephrectomy. It included four observational cohort studies comprising 383 patients.
Robot-assisted ileal ureter replacement for complex ureteral strictures: a systematic review and single-arm meta-analysis of surgical and functional outcomes.
This systematic review and single-arm meta-analysis assessed surgical and functional outcomes after robot-assisted ileal ureter replacement (RIUR) in adults with complex ureteral strictures.
Stereotactic body radiotherapy versus conventional external beam radiotherapy for bone metastases: a meta-analysis.
This systematic review and meta-analysis compared stereotactic body radiotherapy (SBRT) with conventional external beam radiotherapy (cEBRT) for painful bone metastases, pooling comparative clinical studies using…
Predicting IGD treatment outcomes across interventions using a whole-brain functional connectome biomarker.
This clinical trial study examined whether resting-state whole-brain functional connectivity could predict symptom improvement in 90 individuals with internet gaming disorder (IGD) receiving mindfulness meditation…
Robotic Parenchyma-Preserving Pancreatic Resection for Focal Congenital Hyperinsulinism in an Infant.
An infant weighing 4.6 kg with focal congenital hyperinsulinism underwent robot-assisted, parenchyma-preserving pancreatic resection using indocyanine green, intraoperative ultrasound, and suture-based retraction.
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