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1778 articles
September 202624
Neurosyphilis Concurrently Presenting With Limbic Encephalitis and Normal Pressure Hydrocephalus: A Case Report.
A 47-year-old man presented with cognitive decline, gait disturbance, and urinary incontinence. Imaging revealed ventricular enlargement and high signal intensity in the medial temporal lobes.
Epigenetic Programming of Stress-Response Systems: A Systematic Review of How Early Life Stress Shapes Developmental Trajectories of Mental Health.
This systematic review examines how early life stress (ELS) influences mental health development through epigenetic mechanisms, particularly DNA methylation, in 14 empirical human studies.
Hypofractionated versus conventional fractionated postmastectomy radiotherapy for patients with high-risk breast cancer (CHN HYPOPMRT): 10-year outcomes from a randomised, non-inferiority, open-label, phase 3 trial.
This phase 3 randomized trial compared hypofractionated (43.5 Gy in 15 fractions) and conventional (50 Gy in 25 fractions) postmastectomy radiotherapy in 810 women with high-risk breast cancer.
A Case Report to Explore A Wrong-Site Surgery Error.
A case of wrong-site surgery involved an incorrect nerve block performed during a nonemergent orthopedic procedure. Despite some verification steps being completed, the incident was attributed to lapses in established…
Prophylactic Immediate Lymphatic Reconstruction for the Prevention of Secondary Lymphedema: A Systematic Review and Meta-Analysis of Comparative Studies.
This systematic review and meta-analysis evaluated the effectiveness of prophylactic lymphovenous shunting (LVS) in preventing secondary lymphedema in 2261 patients undergoing axillary and inguinal lymph node…
Long-term clinical outcomes of stem cell-based interventions in Crohn's-related perianal fistula: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the long-term outcomes of stem cell-based interventions for Crohn's disease-related perianal fistulas in 750 patients.
Continuous Versus Routine EEG in Critically Ill Patients Without Primary Neurologic Condition: Analysis of a Randomized Controlled Trial.
This post hoc analysis of the multicenter randomized CERTA trial evaluated the effectiveness of continuous EEG (cEEG) versus routine EEG (rEEG) in critically ill patients without primary neurologic conditions.
Designing Youth Early Intervention in Psychosis Services: A Secondary Framework Synthesis of Organisational Recommendations.
This systematic review synthesized organizational recommendations from 26 international guidelines on early intervention in psychosis (EIP) for youth.
The Effect of Carbetocin on Cardiac Repolarization: A Randomized, Placebo- and Positive-Controlled QT/QTc Study in Healthy Adults.
This randomized controlled trial assessed the impact of a supratherapeutic dose of carbetocin on cardiac repolarization in 42 healthy adults.
Unveiling the Prognostic Power of Circulating Tumor DNA in Multiple Myeloma: A Systematic Review and Updated Meta-Analysis.
This systematic review and meta-analysis evaluated the prognostic significance of circulating tumor DNA (ctDNA) in 948 patients with multiple myeloma (MM).
A Heterozygous Variant in the GABBR2 Gene in a Girl With Clinical Classic Rett Syndrome.
A girl diagnosed with classic Rett syndrome exhibited developmental stagnation, loss of purposeful hand use, stereotypic movements, autonomic dysfunction, and behavioral issues.
The Effect of Emotional Freedom Techniques on Death Anxiety and Cancer-Related Anxiety in Patients Undergoing Oncological Surgery: A Randomized Controlled Trial.
This randomized controlled trial examined the impact of emotional freedom techniques (EFT) on death anxiety and cancer-related anxiety in 120 patients undergoing oncological surgery.
The Effect of Oropharyngeal Colostrum Administration on Early Feeding Skills and Transition to Oral Feeding in Preterm Infants: A Randomized Controlled Trial.
This randomized controlled trial investigated the impact of oropharyngeal colostrum administration on oral feeding readiness in 60 preterm infants (26 0 to 33 6/7 weeks gestation).
Purely transvenous treatment of cervical paraspinal arteriovenous fistulas.
This report details two patients with paraspinal arteriovenous fistulas (PSAVF) treated using a purely transvenous approach.
FOXG1 syndrome: genetic background revealed by trio WES in case of a critically ill neonate.
A male neonate presented with hypotonia and abnormal respiratory effort at birth. Due to the serious and non-specific clinical signs, trio whole-exome sequencing (WES) was performed, revealing a de novo heterozygous…
A rare case of hereditary spastic paraplegia with homozygous mutation in the ZFYVE26 gene.
A 19-year-old female with consanguineous parents presented with gait disturbances, lower limb spasticity, and dysarthria. Neurological examination revealed motor and mental retardation, bilateral lower limb spasticity…
The FIRE technique - A tube ligation alternative.
A patient undergoing glaucoma surgery with a nonvalved glaucoma drainage device (GDD) was treated using the Flanged Intraluminal Ripcord Element (FIRE) technique.
Autologous rotational partial thickness scleral flap - A salvage technique for late leaking blebs with scleral fistula.
Two patients with late leaking blebs complicated by scleral fistulae underwent a modified autologous rotational partial-thickness scleral flap procedure.
Effect of strengths-based, tiered, accessible resources and supports (STARS) for Kids project, a codesigned hybrid service delivery framework to identify and support child development, parent mental health and psychosocial needs among parents and carers of children aged 6 months to 3 years: a randomised controlled trial protocol.
This randomized controlled trial protocol evaluates the STARS for Kids model, designed to enhance early identification and support for child development and parental mental health among parents of children aged 6 months…
Sarcopenia in Indian adults with type 2 diabetes: a systematic review and meta-analysis of prevalence and associated factors.
This systematic review and meta-analysis assessed the prevalence of sarcopenia among Indian adults with type 2 diabetes mellitus (T2DM).
Lumbar spinal brucellosis presenting as an atypical epidural abscess.
A man in his 50s presented with low back pain and lower limb radiculopathy. MRI revealed a ventral epidural collection at L4-L5, resembling a sequestered disc fragment, without significant vertebral or disc involvement.
Uveitis as a class effect of Bruton tyrosine kinase inhibitors: ibrutinib and zanubrutinib ocular toxicity.
A man in his early 50s with Waldenström macroglobulinaemia developed posterior uveitis while on ibrutinib, characterized by vitreous and retinal infiltrates.
Autologous retinal transplant for macular hole in retinal detachment following bag-intraocular lens complex dislocation.
An elderly patient in their late 80s presented with total retinal detachment and a macular hole following pars plana vitrectomy for a dislocated capsular bag-intraocular lens complex.
Rotational thromboelastometry guided transfusion in venom-induced consumptive coagulopathy following a haemotoxic snakebite.
A woman in her 30s presented with severe haemotoxic snake envenoming and venom-induced consumptive coagulopathy (VICC), leading to early multiorgan involvement.
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