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1617 articles
October 202624
Extracorporeal photopheresis for the treatment of steroid-refractory immune related adverse events from immune checkpoint inhibitor therapy: a multi-center phase Ib/II clinical trial.
This prospective, single-arm, non-randomized phase Ib/II multicentre trial evaluated extracorporeal photopheresis (ECP) for steroid-refractory immune-related adverse events (irAEs) in 30 patients receiving immune…
Fractional CO₂ laser combined with intradermal and topical platelet-rich plasma for hypertrophic scars: a randomized controlled trial.
This prospective, randomized, assessor-blinded trial compared fractional CO₂ laser plus intradermal and topical platelet-rich plasma (PRP) with laser plus saline in 120 patients with hypertrophic scars.
Hematological and biochemical responses to three doses of caffeine during the CrossFit® workout: a randomized, double-blind, crossover trial.
This randomized, double-blind, placebo-controlled crossover trial examined hematological and biochemical responses to caffeine during a 17-minute CrossFit® workout in 26 moderately trained athletes.
Balancing safety and efficacy in photodynamic therapy for facial port-wine stains in children aged 2-7 years: a prospective controlled study of light-intensity optimization.
This open-label, prospective controlled study compared two light intensities for hemoporfin-mediated photodynamic therapy in children aged 2–7 years with facial port-wine stains.
Psychoeducation for posttraumatic stress disorder in adults: a systematic review of formats and delivery approaches.
This systematic review synthesized randomized controlled trials of psychoeducation for adults with PTSD, including interventions delivered alone or as a primary component.
Psychopathological and neuropsychological sequelae in children victimised by intimate partner violence: a clinical case series.
A clinical case series assessed four children aged 5–9 with documented exposure to intimate partner violence, including witnessing violence and, in some cases, direct abuse.
Fatal Occupational Leptospirosis in a Beef Cattle Farmer: Case Report and Epidemiological Investigation.
A 56-year-old beef cattle farmer in Lombardy, Italy, died from occupational leptospirosis. Testing identified a strain of serogroup Javanica, with a microscopic agglutination test titre of 1:3,200 against serovar Poi.
Streptococcus constellatus-Associated Lemierre Syndrome Presenting With Cavitating Septic Pulmonary Emboli Managed by Video-Assisted Thoracoscopy.
A previously healthy 25-year-old man presented with a week of dyspnea, productive cough, fever, and hemoptysis, with severe hypoxemia and respiratory distress.
A Methodological Framework for a Large Language Model Virtual Companion for Older Adults at Risk of Social Isolation.
This paper presents a methodological framework for developing and evaluating a large language model (LLM)-driven virtual companion for older adults at risk of social isolation.
Jidesheng Snake Pills as Adjunctive Therapy for Snakebite: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
This systematic review and meta-analysis assessed randomized evidence for Jidesheng Snake Pills as adjunctive treatment for snakebite. Five unique trials involving 458 participants were included.
Effects of E-Coach-Based Chronic Disease Management on Self-Management, Quality of Life, and Mental Health in Maintenance Hemodialysis Patients.
This randomized controlled trial evaluated a WeChat-based E-Coach programme in 96 patients receiving maintenance hemodialysis, comparing usual care plus E-Coach with usual care alone.
Fosfomycin-induced liver injury in a 17-year-old patient: A case report.
A previously healthy 17-year-old male developed nausea, vomiting, fever, progressive epigastric pain, fatigue, and malaise.
Anatomopathological Aspects and Clinical Correlation of Conjunctival Bleb Fibrosis Following Encapsulation of a Biodegradable Collagen Matrix Implant in Glaucoma Surgery.
Four patients with progressive glaucoma and inadequate intraocular pressure control despite maximal medical therapy underwent non-penetrating deep sclerectomy with a biodegradable collagen-glycosaminoglycan implant and…
Integrated tendon repair and staged skin grafting for a severe forearm degloving injury: A case report from a low-resource setting.
A 21-year-old right-handed man presented two hours after a road traffic collision with extensive degloving of the right forearm, wrist, and dorsal thumb.
Pulmonary infection caused by Nocardia cyriacigeorgica and influenza A virus coinfection in an immunocompetent patient: A case report.
A 60-year-old immunocompetent man without reported underlying pulmonary disease presented with recurrent cough and sputum production over 5 months, worsening respiratory symptoms, and recent fever.
Efficacy and safety of GLP-1 receptor agonists in patients with metabolic dysfunction-associated steatotic liver disease (MASLD) and metabolic dysfunction-associated steatohepatitis (MASH): A systematic review and meta-analysis.
This systematic review and random-effects meta-analysis assessed efficacy and safety of GLP-1 receptor agonists in adults with MASLD or MASH. Nine studies involving 795 participants were included.
Systematic review and meta-analysis of risk factors for oral frailty.
This systematic review and meta-analysis examined factors associated with oral frailty across 14 studies involving 12,297 participants, of whom 4,540 had oral frailty.
Minocycline in acute stroke: A systematic review and meta-analysis of randomized controlled trials and trial sequential analysis.
This systematic review and meta-analysis pooled randomized controlled trials comparing minocycline with control or standard care in acute ischemic and hemorrhagic stroke.
The role of sexual mindfulness in enhancing sexual well-being among breast cancer survivors: A randomized clinical trial.
This randomized clinical trial assessed sexual mindfulness training for sexual well-being among women with breast cancer attending health service centers in Shahrekord, Iran.
Staged limb salvage after an infected full-thickness shoulder-girdle flame burn with osteoarticular exposure in an elderly patient: A case report with 3.5-year follow-up.
A 73-year-old woman with diabetes, hypertension, and cachexia presented about 3 weeks after a flame burn with an extensive infected wound from the neck base to the distal left arm.
Neonatal nemaline myopathy associated with NEB variants and a favorable 3-year outcome: A case report.
A female neonate developed cyanosis, bradycardia, respiratory distress, and hypotonia shortly after birth, with recurrent respiratory deterioration and bulbar feeding and swallowing difficulties.
Primary renal diffuse large B cell lymphoma misdiagnosed as renal cell carcinoma: A case report.
A 78-year-old man presented with 2 weeks of right flank pain radiating to the abdomen; examination was unremarkable. Tests showed mildly elevated lactate dehydrogenase and occult blood in the urine.
Comparative efficacy of common adjuvant treatments after resection of colorectal liver metastases: A systematic review and network meta-analysis.
This systematic review and network meta-analysis compared adjuvant strategies after resection of colorectal liver metastases, including systemic chemotherapy, hepatic arterial infusion chemotherapy (HAIC), and…
Primary tubal choriocarcinoma with extrauterine implantation masquerading as ectopic pregnancy: A case report and literature review.
A 29-year-old woman with irregular menses had extremely high β-human chorionic gonadotropin levels and ultrasonographic findings suggestive of ectopic pregnancy.
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