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1545 articles

October 202624

Case ReportGastroenterologyOpen access

Protein-losing enteropathy as a rare presentation of small bowel T-cell post-transplant lymphoproliferative disease.

A kidney transplant recipient developed episodic diarrhea, with initial investigations showing no bowel pathology. She later developed fluid retention associated with hypoalbuminemia, and technetium-99m human serum…

CEN Case RepOct 27, 2026Read case
Clinical ResearchOrthopedic SurgeryOpen access

Closed percutaneous reduction versus mini-open sinus tarsi approach for fixation of displaced intra-articular calcaneal fractures: a systematic review and meta-analysis.

This systematic review and meta-analysis compared closed percutaneous reduction (PR) with the mini-open sinus tarsi approach (STA) for acute displaced intra-articular calcaneal fractures.

Eur J Orthop Surg TraumatolOct 27, 2026Read summary
Clinical ResearchGeneral Surgery

Associating liver partition and portal vein ligation for staged hepatectomy procedure versus conventional two-stage hepatectomy for colorectal liver metastasis.

This Cochrane systematic review and meta-analysis assessed ALPPS versus conventional two-stage hepatectomy in adults with colorectal liver metastases and an estimated future liver remnant below 30% of total liver…

Cochrane Database Syst RevOct 27, 2026Read summary
Clinical ResearchPediatrics

Air versus supplemental oxygen for resuscitation of term or late preterm infants at birth.

This Cochrane systematic review and meta-analysis assessed randomised and quasi-randomised trials comparing air with supplemental oxygen for resuscitation at birth in term and late preterm infants needing respiratory…

Cochrane Database Syst RevOct 27, 2026Read summary
Clinical ResearchInfectious Diseases

Measles transmission-related epidemiological parameter estimates: a systematic review and meta-analysis.

This systematic review and meta-analysis synthesized English- and French-language primary studies reporting measles transmission-related epidemiological parameters, identified through 14 May 2024.

Epidemiol InfectOct 27, 2026Read summary
Case ReportInfectious Diseases

Isolated Disturbance of Consciousness as Initial Presentation of Staphylococcus aureus Endocarditis: A Case Report With Brief Literature Review.

A man in his 50s presented with isolated disturbance of consciousness and no reported fever, although his admission temperature was 38°C.

Am J Case RepOct 27, 2026Read case
Clinical ResearchUrologyOpen access

Robot-assisted versus open partial nephrectomy in patients with a solitary kidney: a systematic review and meta-analysis of perioperative and functional outcomes.

This systematic review and meta-analysis compared robot-assisted partial nephrectomy (RAPN) with open partial nephrectomy (OPN) for tumors in a solitary kidney.

J Robot SurgOct 27, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Safety and efficacy of dual immune checkpoint inhibition for melanoma brain metastases and its comparison to ICI monotherapy: A systematic review and meta-analysis.

This PRISMA-based systematic review and meta-analysis pooled prospective and retrospective studies of adults with cutaneous or mucosal melanoma brain metastases treated with dual immune checkpoint inhibition (ICI), and…

Neurosurg RevOct 27, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Body image distress in women and men with advanced pancreatic cancer approaching death - post-hoc analyses from the MISTRAL-trial.

This post-hoc analysis of data from the MISTRAL trial examined changes in body image distress and weight worries among 125 women and men with pancreatic cancer during the six months before death.

Support Care CancerOct 27, 2026Read summary
Clinical ResearchPediatricsOpen access

Permissive Blood Pressure Targets in Pediatric Critical Care: The PRESSURE Randomized Clinical Trial.

The multicenter, unblinded pragmatic randomized PRESSURE trial compared a permissive mean arterial pressure (MAP) target (greater than the fifth percentile for age) with usual physician-set targets in hypotensive…

JAMAOct 27, 2026Read summary
Clinical ResearchObstetrics & GynecologyOpen access

Intrauterine Mepivacaine Instillation vs Placebo for Pain During IUD Placement: A Randomized Clinical Trial.

This multicentre, double-blind, randomised, placebo-controlled trial tested intrauterine mepivacaine before IUD placement in nulliparous individuals aged 18 to 31 years at 11 Swedish clinics.

JAMAOct 27, 2026Read summary
Clinical ResearchVascular SurgeryOpen access

Revascularization of Asymptomatic Carotid Artery Stenosis: Cognitive Results of the CREST-2 Randomized Trials.

This prespecified cognitive-outcomes analysis of the multicentre, randomised CREST-2 trials assessed patients aged 35 years or older with at least 70% asymptomatic carotid stenosis.

JAMAOct 27, 2026Read summary
Clinical ResearchVascular SurgeryOpen access

Revascularization in Asymptomatic Carotid Artery Stenosis With Hemodynamic Impairment and Cognitive Outcomes: The CREST-H Substudy of the CREST-2 Randomized Clinical Trial.

This multicenter substudy of a phase 3 randomized clinical trial examined whether baseline cerebral hemodynamic impairment modified cognitive outcomes after carotid revascularization in adults with high-grade…

JAMAOct 27, 2026Read summary
Case ReportDermatology

Long-term remission of severe psoriasis following CD19-directed chimeric antigen receptor T-cell therapy for follicular lymphoma.

A 60-year-old woman with a 49-year history of severe plaque psoriasis received autologous CD19-directed CAR-T therapy for follicular lymphoma.

Clin Exp DermatolOct 27, 2026Read case
Case ReportDermatology

Cutaneous features of SDR9C7 variants in eight individuals with autosomal recessive nonsyndromic epidermal differentiation disorders.

Eight individuals with SDR9C7 variants and nonsyndromic epidermal differentiation disorders had scaling and erythema, commonly with fine scale, hyperlinear palms, and greater involvement of the extremities, particularly…

Clin Exp DermatolOct 27, 2026Read case
Clinical ResearchDermatology

The follicular microbiome in hair-follicle-associated inflammatory diseases: a systematic review.

This systematic review qualitatively synthesized culture-independent studies of the bacterial hair-follicle microbiome in inflammatory hair-follicle-associated diseases.

Clin Exp DermatolOct 27, 2026Read summary
Clinical ResearchDermatology

Efficacy and safety of icotrokinra for plaque psoriasis: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed icotrokinra, an oral IL-23 receptor antagonist, in adolescents and adults with moderate-to-severe plaque psoriasis.

Clin Exp DermatolOct 27, 2026Read summary
Clinical ResearchEndocrinology

Berberine improves diabetic foot ulcer healing after tibial transverse osteotomy by inhibiting the PDGF-B/PDGFRβ signaling pathway .

This prospective, single-centre, randomized, placebo-controlled trial evaluated local berberine injections added to tibial transverse osteotomy (TTO) in patients with Wagner grade 2–4 diabetic foot ulcers.

Pak J Pharm SciOct 26, 2026Read summary
Clinical ResearchOrthopedic Surgery

Efficacy and safety study of diclofenac epolamine topical patch in accelerating rehabilitation of moderate hamstring strain: A randomized controlled trial .

This single-centre, double-blind, placebo-controlled randomised trial evaluated topical diclofenac epolamine alongside rehabilitation in 120 patients with moderate hamstring strain.

Pak J Pharm SciOct 26, 2026Read summary
Clinical ResearchPhysical Medicine & RehabilitationOpen access

A Short Evidence-Based, Belief-Focused Educational Video Improves Back Pain Beliefs but Not Lifting Behaviour in Healthy Office Workers: An Exploratory Randomised Controlled Trial.

This assessor-blind exploratory randomised controlled trial assigned 50 healthy office workers to a brief video about back pain beliefs and management or an anatomy-video control.

Musculoskeletal CareOct 26, 2026Read summary
Clinical ResearchNeurology

From Bench to Bedside: Evaluating the Accuracy of Clinical Sensory Testing in Detecting Somatosensory Disorders. A Systematic Review.

This systematic review assessed the diagnostic accuracy of clinical sensory tests (CSTs) for somatosensory disorders across populations and conditions, comparing test results with reference standards.

Musculoskeletal CareOct 26, 2026Read summary
Clinical ResearchPulmonology

Local Delivery of Interferon-β1a for Respiratory Viral Infections: A Systematic Review.

This PRISMA-guided systematic review assessed locally delivered intranasal or inhaled interferon-β1a for respiratory viral infections, covering clinical trials and experimental evidence.

Rev Med VirolOct 26, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Consequences of opioid exposure in disease-free cancer survivors: A systematic literature review.

This systematic literature review examined the consequences of persistent opioid exposure after curative-intent treatment in disease-free cancer survivors.

J Manag Care Spec PharmOct 26, 2026Read summary
Clinical ResearchPediatrics

Effectiveness of Exercise Snacks in Mitigating Adolescent Problematic Smartphone Use: A Four-Wave Cluster Randomized Controlled Trial.

This four-wave cluster randomized controlled trial tested whether brief, vigorous activity breaks could reduce problematic smartphone use among 386 adolescents in 12 secondary-school classes.

Scand J Med Sci SportsOct 26, 2026Read summary

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