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1704 articles

October 202624

Clinical ResearchGeneral Surgery

Restorative resection in robot-assisted versus laparoscopic total mesorectal excision: systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the outcomes of robot-assisted total mesorectal excision (R-TME) versus laparoscopic total mesorectal excision (L-TME) in rectal cancer surgery, involving 7133 patients…

Br J SurgOct 5, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Integration of Virtual and Augmented Reality Into Obstetric Nursing and Midwifery Education: Systematic Review.

This systematic review evaluated the use of virtual reality (VR) and augmented reality (AR) in obstetric nursing and midwifery education, analyzing four studies with 634 participants.

JMIR NursOct 5, 2026Read summary
Case ReportEndocrinology

Off-label palopegteriparatide for severe pediatric postsurgical hypocalcemia.

A 14-year-old boy with Graves’ disease developed profound hypocalcemia after total thyroidectomy, with serum calcium 5.9 mg/dL, ionized calcium 0.83 mmol/L, and undetectable parathyroid hormone.

Eur J EndocrinolOct 5, 2026Read case
Clinical ResearchGastroenterology

SYSTEMATIC REVIEW AND BRAZILIAN EXPERT CONSENSUS ON THE USE OF BIOSIMILARS IN INFLAMMATORY BOWEL DISEASE: BRAZILIAN ORGANIZATION FOR CROHN'S AND COLITIS.

This systematic review and Brazilian expert consensus assessed biosimilar use in inflammatory bowel disease (IBD), addressing clinical, therapeutic, and economic questions.

Arq GastroenterolOct 5, 2026Read summary
Clinical ResearchOphthalmology

Microperimetry Sensitivity Changes at the Functional Transition Zone and at the EZ Margins in X-Linked Retinitis Pigmentosa Treated With Gene Therapy.

This post-hoc analysis of the randomized Skyline trial examined how photoreceptor ellipsoid-zone (EZ) structure related to microperimetry sensitivity in eyes with X-linked retinitis pigmentosa treated with gene therapy.

Transl Vis Sci TechnolOct 5, 2026Read summary
Case ReportObstetrics & GynecologyOpen access

Fetal hemothorax due to intrapleural rupture of a small anterior thoracic lymphatic malformation: a case report.

A pregnant woman was referred at 26 weeks after bloody fetal pleural fluid was obtained by thoracentesis. Ultrasound showed right pleural effusion and a small, avascular heterogeneous area in the anterior chest wall…

J Med Case RepOct 5, 2026Read case
Clinical ResearchRheumatologyOpen access

Drug treatments for fibromyalgia: systematic review and network meta-analysis of randomised trials.

This systematic review and network meta-analysis compared drug treatments for fibromyalgia in adults, including evidence from 151 randomised trials involving 32 592 participants.

BMJ MedOct 5, 2026Read summary
Case ReportAllergy & ImmunologyOpen access

Adult-Onset Henoch-Schönlein Purpura Triggered by Isotretinoin with Persistent Polyarthritis and Isolated Cutaneous-Gastrointestinal Involvement: A Case Report.

A 30-year-old woman developed palpable purpura, abdominal pain, and symmetric polyarthritis three weeks after starting isotretinoin.

Int Med Case Rep JOct 5, 2026Read case
Case ReportAnesthesiologyOpen access

Remimazolam ED95 for Preoperative Sedation in Children with Obstructive Sleep Apnea, with Obesity or a Reference-Range BMI: A Biased-Coin Dose-Finding Study.

Obesity may alter total-body-weight dosing of remimazolam, whereas obstructive sleep apnea narrows the respiratory safety margin.

Drug Des Devel TherOct 5, 2026Read case
Case ReportAllergy & ImmunologyOpen access

Anaphylaxis Following Intravenous Methylprednisolone Sodium Succinate: A Case Report.

A 45-year-old woman with rheumatoid arthritis developed generalized pruritic erythema and raised lesions, dyspnea, hypoxemia, bradycardia, and reduced consciousness within 5 minutes of starting intravenous…

Int Med Case Rep JOct 5, 2026Read case
Clinical ResearchGeneral Surgery

Impact of Side-to-Side Versus End-to-Side Gastrojejunostomy on the Rate of Delayed Gastric Emptying After Pancreatoduodenectomy (IPAD study): A Randomized Controlled Trial.

The IPAD study was a prospective, open-label randomized trial at two high-volume pancreatic centers in France, comparing side-to-side with end-to-side gastrojejunostomy in adults undergoing pancreatoduodenectomy for…

Ann SurgOct 5, 2026Read summary
Clinical ResearchInfectious Diseases

A phase III randomized study: Immunogenicity and safety of a quadrivalent meningococcal conjugate vaccine in healthy adults, adolescents, and children in India and healthy adolescents and children in South Africa.

This Phase III randomized controlled trial assessed the immunogenicity and safety of a single dose of MenACYW-TT in healthy adults, adolescents, and children in India and in adolescents and children in South Africa.

VaccineOct 5, 2026Read summary
Clinical ResearchPsychiatry

Dynamic change patterns in suicidal ideation differ in Brief Cognitive Behavioral Therapy (BCBT) and Present-Centered Therapy (PCT).

This randomized clinical trial examined how five dimensions of suicidal ideation changed during Brief Cognitive Behavioral Therapy (BCBT) versus Present-Centered Therapy (PCT) among high-risk U.S.

Behav Res TherOct 5, 2026Read summary
Clinical ResearchRadiology (Diagnostic)

The utility of magnetic resonance imaging of the spinal cord in paediatric transverse myelitis: A systematic review.

This systematic review assessed spinal cord MRI findings, agreement with CSF inflammation, and prognostic associations in children with monophasic acute transverse myelitis.

Mult Scler Relat DisordOct 5, 2026Read summary
Clinical ResearchPhysical Medicine & Rehabilitation

Adjunctive neuromuscular electrical stimulation and cognitive-motor interference during gait in older inpatients.

This exploratory analysis of a pragmatic pilot trial examined whether adjunctive neuromuscular electrical stimulation (NMES) was associated with changes in cognitive-motor interference during gait among older inpatients…

Exp GerontolOct 5, 2026Read summary
Clinical ResearchPsychiatry

Nutraceuticals and phytoceuticals in the treatment of bipolar disorder: A systematic review and network meta-analysis.

This systematic review and network meta-analysis assessed randomized controlled trials of nutraceuticals and phytoceuticals for bipolar disorder. Twenty-eight trials involving 2,222 participants evaluated 22 treatments.

Eur NeuropsychopharmacolOct 5, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Preoperative CA15-3 as a predictor of axillary lymph node metastasis and prognosis in women with breast cancer: a GRADE-assessed systematic review and meta-analysis.

This GRADE-assessed systematic review and random-effects meta-analysis examined cohort studies of preoperative CA15-3 in women with breast cancer, assessing survival and metastatic outcomes.

Breast CancerOct 5, 2026Read summary
Clinical ResearchCardiology

Mechanical Thrombectomy Versus Anticoagulation Alone in Intermediate-High Risk PE: Improved Functional 90-Day Outcomes in STORM-PE RCT.

STORM-PE was a multicentre randomised trial comparing computer-assisted vacuum thrombectomy (CAVT) plus anticoagulation with anticoagulation alone in 100 patients with acute intermediate-high-risk pulmonary embolism.

JACC Cardiovasc IntervOct 5, 2026Read summary
Case ReportCardiology

No-Stent Management of High Coronary Thrombus Burden in Young Patients with STEMI: A Four-Case Series.

The report describes four young male patients (≤50 years old) presenting with STEMI and a large coronary thrombus without clearly demonstrated flow-limiting severe atherosclerotic stenosis.

Turk Kardiyol Dern ArsOct 5, 2026Read case
Clinical ResearchNeurology

Frontal aperiodic activity and sensorimotor theta clustering are differentially modulated by tDCS during proprioceptive training in Parkinson's disease: An EEG study.

This randomized controlled EEG study examined whether anodal transcranial direct current stimulation (tDCS) over the supplementary motor area altered neural measures during proprioceptive training in 24 people with…

NeuroscienceOct 5, 2026Read summary
Clinical ResearchHematologyOpen access

Interference of iron deficiency in glycated hemoglobin testing and its clinical implications: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the impact of iron deficiency anemia (IDA) and latent iron deficiency (LID) on glycated hemoglobin (HbA1c) concentrations.

Biochem Med (Zagreb)Oct 4, 2026Read summary
Clinical ResearchAnesthesiology

Repeated remimazolam sedation for interstitial brachytherapy in cervical cancer: a randomized controlled trial.

This randomized controlled trial evaluated the safety and efficacy of repeated remimazolam sedation compared to propofol in 100 patients with cervical cancer undergoing interstitial brachytherapy.

Ann MedOct 4, 2026Read summary
Clinical ResearchHematologyOpen access

N-acetylcysteine mouthwash for prevention of oral mucositis in hematopoietic cell transplant recipients: a double-blind randomized controlled trial.

This double-blind randomized controlled trial evaluated the efficacy of N-acetylcysteine (NAC) mouthwash in preventing oral mucositis (OM) in 106 hematopoietic cell transplant (HCT) recipients.

Support Care CancerOct 4, 2026Read summary
Case ReportOtolaryngology (ENT)

Image-Guided Cervicotomy and Recurrent Laryngeal Nerve Reinnervation in Zone II Glass Neck Trauma: A Case Report.

A 45-year-old woman with penetrating neck trauma from glass fragments presented hemodynamically stable, without airway compromise. Imaging revealed multiple retained glass foreign bodies but no major vascular injuries.

Am J Case RepOct 4, 2026Read case

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