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785 articles

September 202624

Clinical ResearchOncology (Medical)

Multidisciplinary Rehabilitation Following Upper Gastrointestinal Cancer Surgery (RESTORE II): A Definitive Randomized Controlled Trial.

RESTORE II was a randomized controlled trial comparing a 12-week multidisciplinary rehabilitation program with standard care in disease-free patients at least 3 months after upper gastrointestinal cancer resection.

Ann SurgSep 2, 2026Read summary
Clinical ResearchEndocrinologyOpen access

A 12-week, double-blind, quasi-randomized, placebo-controlled study to evaluate the efficacy and safety of Coleus forskohlii (Forcslim) on body weight loss.

This 12-week, double-blind, quasi-randomized, placebo-controlled trial evaluated the efficacy and safety of Coleus forskohlii (Forcslim) in 60 overweight individuals aged 20-70.

J Int Soc Sports NutrSep 1, 2026Read summary
Clinical ResearchCardiology

Comparative Cardiovascular Outcomes of GLP-1 Receptor Agonists Versus Bariatric Surgery: A Systematic Review and Network Meta-Analysis.

This systematic review and network meta-analysis evaluated cardiovascular outcomes of bariatric surgery (BS) versus glucagon-like peptide-1 receptor agonists (GLP-1RAs) in obese patients.

Endocrinol Diabetes MetabSep 1, 2026Read summary
Clinical ResearchPulmonologyOpen access

CFTR Modulator Therapy and Aerobic Fitness Changes in Aerobic Fitness Following Initiation of CFTR Modulator Therapy: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated the impact of CFTR modulator therapy on aerobic fitness in individuals with cystic fibrosis (n=578).

Pediatr PulmonolSep 1, 2026Read summary
Clinical ResearchGastroenterology

Effect of Post-Discharge Oral Nutritional Supplements on Nutritional Status in Patients after Gastrectomy: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated the impact of post-discharge oral nutritional supplements (ONS) on nutritional status in 1,736 patients after gastrectomy for gastric cancer.

J Vis ExpSep 1, 2026Read summary
Clinical ResearchGastroenterologyOpen access

Ameliorating Effects and Autonomic Mechanisms of Transcutaneous Auricular Vagus Nerve Stimulation on Abdominal Pain in Patients With Functional Dyspepsia and Irritable Bowel Syndrome.

This randomized controlled trial evaluated the effects of transcutaneous auricular vagus nerve stimulation (taVNS) on abdominal pain and quality of life in 64 patients with functional dyspepsia (FD) and irritable bowel…

Neurogastroenterol MotilSep 1, 2026Read summary
Case ReportAllergy & Immunology

Suspected menopause nutraceutical-induced eosinophilic ascites: a rare clinical presentation.

A middle-aged woman presented with a 2-month history of ascites and marked peripheral eosinophilia (49%). Analysis of her ascitic fluid revealed 90% eosinophils, with no malignancy detected.

BMJ Case RepSep 1, 2026Read case
Clinical ResearchGastroenterologyOpen access

Probiotics Accelerate Microbiota and Metabolic Pathway Recovery Following Colonoscopy Bowel Preparation in Ulcerative Colitis.

This randomized controlled trial investigated the impact of probiotic supplementation on microbiota recovery following polyethylene glycol (PEG)-based bowel preparation in 79 participants, including 39 patients with…

Med Sci MonitSep 1, 2026Read summary
Clinical ResearchGeneral SurgeryOpen access

Efficacy of FiLaC in different types of anal fistula. A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the efficacy of Fistula Tract Laser Closure (FiLaC) across different types of anal fistula.

Lasers Med SciSep 1, 2026Read summary
Clinical ResearchGastroenterologyOpen access

Early ileocaecal resection versus biologics therapy for localized Crohn disease: A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated early ileocaecal resection versus biologics therapy in 1,644 patients with localized Crohn's disease.

Colorectal DisSep 1, 2026Read summary
Clinical ResearchGastroenterologyOpen access

Immediate Versus On-Demand Direct Endoscopic Necrosectomy for Necrotizing Pancreatitis: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated the efficacy and safety of immediate versus on-demand direct endoscopic necrosectomy (DEN) for necrotizing pancreatitis in 616 patients across seven studies.

United European Gastroenterol JSep 1, 2026Read summary
Clinical ResearchMedical GeneticsOpen access

Phase 3 Randomized Trial Results of DTX401 AAV Gene Therapy for the Treatment of GSDIa.

This phase 3 randomized controlled trial evaluated the efficacy of DTX401 gene therapy in patients aged 8 years and older with glycogen storage disease type Ia (GSDIa).

J Inherit Metab DisSep 1, 2026Read summary
Case ReportOncology (Medical)

A Case of Concurrent Liver Metastases from Colorectal and Breast Cancer Diagnosed Using Percutaneous Tumor Biopsy.

A 71-year-old woman with metastatic lobular breast carcinoma developed new liver lesions after initial treatment. Imaging revealed multiple bilobar liver tumors with distinct patterns, prompting further investigation.

Anticancer ResSep 1, 2026Read case
Clinical ResearchGastroenterology

The use of digital health tools in the management of inflammatory bowel disease: a systematic review.

This systematic review examined the use of digital health tools (DHTs) in managing inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis.

Minerva Gastroenterol (Torino)Sep 1, 2026Read summary
Clinical ResearchGastroenterologyOpen access

Submucosal Lidocaine Injection in Colonic Endoscopic Submucosal Dissection: A Single-Center, Double-Blind, Randomized Controlled Trial.

This single-center, double-blind, randomized controlled trial evaluated the efficacy and safety of submucosal lidocaine injection during colonic endoscopic submucosal dissection (ESD) in 110 patients.

Dig EndoscSep 1, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Sexual dysfunction outcomes and reporting disparities after multimodal treatment for rectal cancer: A systematic review and narrative synthesis.

This systematic review evaluated sexual dysfunction outcomes after rectal cancer treatment, highlighting significant reporting disparities between sexes.

Colorectal DisSep 1, 2026Read summary
Clinical ResearchPediatricsOpen access

Outcomes of ABO-Incompatible Versus ABO-Compatible Liver Transplantation in Pediatric Recipients: An Updated Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated outcomes of ABO-incompatible (ABO-i) versus ABO-compatible (ABO-c) liver transplantation in pediatric recipients.

Pediatr TransplantSep 1, 2026Read summary
Case ReportOncology (Medical)

Case report of an unusual cecal metastasis of a primary cervical squamous cell carcinoma.

A patient with cervical squamous cell carcinoma presented with cecal metastasis, identified as focal wall thickening and a cystic lesion via PET/CT.

Taiwan J Obstet GynecolSep 1, 2026Read case
Clinical ResearchGastroenterologyOpen access

Acetate- Versus Lactate-Buffered Crystalloids for Prevention of Post-ERCP Pancreatitis in Patients Without Access to Rectal NSAIDs: A Multicentre Double-Blind Randomized Trial.

This multicentre double-blind randomized trial compared lactated Ringer's solution (LR) and acetate-buffered crystalloid (AC) for preventing post-ERCP pancreatitis (PEP) in 813 adults at moderate-to-high risk.

United European Gastroenterol JSep 1, 2026Read summary
Clinical ResearchOncology (Medical)

Durvalumab and tremelimumab, with or without lenvatinib, combined with transarterial chemoembolisation in participants with embolisation-eligible hepatocellular carcinoma (EMERALD-3): a global, randomised, open-label, sponsor-blinded, phase 3 study.

The EMERALD-3 study evaluated the efficacy and safety of combining STRIDE (tremelimumab and durvalumab) with or without lenvatinib and transarterial chemoembolisation (TACE) in patients with embolisation-eligible…

Lancet OncolSep 1, 2026Read summary
Clinical ResearchCardiology

Time-varying cardiovascular risk of febuxostat vs. allopurinol in gout: a one-stage meta-analysis.

This meta-analysis evaluated the cardiovascular and mortality risks of febuxostat compared to allopurinol in gout patients, using reconstructed individual participant data from four studies (n=19,090).

Rheumatology (Oxford)Sep 1, 2026Read summary
Clinical ResearchGastroenterologyOpen access

Naltrexone Is Superior to Placebo for Abstinence and Craving Reduction in Alcohol-Associated Cirrhosis: NAL-CI Trial.

The NAL-CI trial evaluated the efficacy and safety of naltrexone in 100 patients with compensated alcohol-associated cirrhosis and alcohol use disorder.

Liver IntSep 1, 2026Read summary
Clinical ResearchInfectious DiseasesOpen access

Acceptability and Effectiveness of Point-of-Care HCV Testing in Low- and Middle-Income Countries: A Systematic Review.

This systematic review evaluated the effectiveness and acceptability of Point-of-Care (POC) HCV testing in low- and middle-income countries (LMICs).

Liver IntSep 1, 2026Read summary
Clinical ResearchGastroenterologyOpen access

Risk of Liver Cancer From Major Causes Compared to Smoking and Lung Cancer: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated the risk of liver cancer associated with HBV, HCV, HDV, MASH, and alcohol consumption compared to smoking and lung cancer.

J Viral HepatSep 1, 2026Read summary

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