Trending archive
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782 articles
September 20263
A global overview of microsporidia infection in HIV/AIDS patients: an updated systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the prevalence and species distribution of microsporidia in HIV/AIDS patients, analyzing 39 studies from 18 countries.
The Great Imitator: Syphilitic Hepatitis Presenting as a Mimic to Autoimmune Liver Disease.
A 34-year-old male on PrEP for HIV presented with epigastric pain and constitutional symptoms. Laboratory tests showed elevated liver enzymes and positive smooth muscle antibodies, suggesting autoimmune hepatitis.
Co-occurrence of pfkelch13 and pfmdr1 variants in a recurrent Plasmodium falciparum infection following standard artemether-lumefantrine treatment.
A patient with metabolic comorbidities developed recurrent Plasmodium falciparum infection after standard artemether-lumefantrine treatment.
August 202621
Association between Chagas disease and the occurrence of stroke: systematic review with meta-analysis.
This systematic review and meta-analysis examined the association between Chagas disease and stroke, including 7 studies. The analysis found that individuals with Chagas disease had a 1.92 times higher risk of stroke…
Proton pump inhibitors in invasively ventilated patients with SARS-CoV-2: a substudy of the re-evaluating the inhibition of stress erosions trial.
This substudy of the REVISE trial evaluated the effects of pantoprazole in 532 mechanically ventilated patients with SARS-CoV-2.
Bilateral granulomatous uveitis mimicking tuberculosis: an atypical ocular presentation of biopsy-proven disseminated histoplasmosis.
A middle-aged immunocompetent male farmer presented with acute bilateral visual loss, redness, and floaters. Examination revealed bilateral granulomatous anterior uveitis with dense vitritis and significant anterior…
Septic Spontaneous Abortion Associated With Intrauterine Fetal Death at 8 Weeks of Gestation Complicated by Myometritis and Bilateral Psoas Muscle Abscess: A Case Report.
A 34-year-old woman presented with severe lower back pain and was diagnosed with septic abortion associated with intrauterine fetal death at 8 weeks of gestation.
Evaluation of inactivated and live attenuated, tetravalent dengue vaccine prime-boost strategies in a randomized, open-label, phase I study: implications for understanding immune correlates of protection.
This randomized, open-label, phase I study evaluated the immune responses elicited by a tetravalent purified inactivated vaccine (PIV) prime and a live attenuated vaccine (LAV) boost in 40 healthy adults.
Bivalent RSV Prefusion F Vaccine to Prevent Hospitalizations in Adults.
This randomized controlled trial evaluated the bivalent RSV prefusion F (RSVpreF) vaccine's effectiveness in preventing RSV-related hospitalizations among adults in Denmark and Spain.
Durability of RSV Prefusion F Vaccine Protection across Two RSV Seasons.
This randomized controlled trial evaluated the durability of protection from the RSV prefusion F vaccine (RSVpreF) in adults aged 60 and older across two RSV seasons.
Severe Plasmodium falciparum malaria with marked ADAMTS13 reduction and secondary microangiopathic features: A case report.
A 46-year-old man returning from Nigeria presented with severe Plasmodium falciparum malaria after 11 days of intermittent fever, jaundice, and dark urine.
Response-Tailored or Standard-Duration Antibiotic Treatment for Infective Endocarditis.
This international, open-label randomized trial compared response-tailored with standard-duration antibiotic therapy in clinically stable adults with left-sided infective endocarditis caused by Staphylococcus aureus…
Autodissemination stations suppress Aedes notoscriptus mosquitoes and reduce Buruli ulcer risk in urban Australia: a randomized controlled field trial.
This randomized controlled trial evaluated the effectiveness of autodissemination mosquito control stations in reducing Aedes notoscriptus populations and Buruli ulcer risk in urban Melbourne, Australia.
Immunomodulation Therapy to Treat Severe Malaria With Multiple Organ Failure.
A 5-year-old girl returning from the Democratic Republic of the Congo presented with fever, shock, 10.9% parasitemia, acute kidney injury, and multiple organ dysfunction.
A multi-center, open-labelled, randomized controlled extended phase III non-inferiority clinical trial to evaluate the immunogenicity and tolerability of poliomyelitis vaccine (Vero cells), inactivated, Sabin strains administered with or without routine infant vaccines.
This multi-center, open-label, randomized controlled trial evaluated the immunogenicity and tolerability of inactivated poliomyelitis vaccine (sIPV) administered with or without routine infant vaccines in 1442 healthy…
Traditional, complementary, and integrative medicine therapies for mild/moderate acute COVID-19: a systematic review and network meta-analysis.
This systematic review and network meta-analysis evaluated the effectiveness of Traditional, Complementary, and Integrative Medicine (TCIM) therapies for mild/moderate acute COVID-19 in 18,627 patients across 69 trials.
Malaria Vaccine Rollout in Nigeria: Current Status and Challenges.
This systematic review examined implementation, awareness, acceptance, willingness to pay, and health system readiness for malaria vaccine rollout in Nigeria.
Impact of renal impairment on pharmacokinetics, safety, and tolerability of funobactam, combined with imipenem and cilastatin.
This phase 1, open-label study assessed the pharmacokinetics and safety of a single intravenous dose of funobactam with imipenem and cilastatin in participants across five renal-function categories, including end-stage…
Risk factors for invasive yeast infections in adult patients with hematological malignancies and/or stem cell transplant: systematic literature review and meta-analysis.
This systematic review and meta-analysis examined risk factors for invasive yeast infections (IYI) in adults with hematological malignancies or undergoing hematopoietic stem cell transplantation.
Safety and immunogenicity of an mRNA COVID-19 vaccine administered to adults: A phase 2, randomized, active-controlled trial.
This phase 2, randomized, active-controlled trial evaluated the safety and immunogenicity of two investigational mRNA COVID-19 vaccines in healthy adults aged 18 and older who had completed their primary vaccination…
Secondary Hemophagocytic lymphohistiocytosis in an immunocompetent adult: a case report distinguishing sarcoidosis from histoplasmosis.
A 73-year-old immunocompetent male presented with lethargy and poor oral intake, initially diagnosed with sarcoidosis. Clinical evaluation revealed fever, splenomegaly, pancytopenia, and elevated inflammatory markers.
Prognostic value of the lactate-to-albumin ratio in adult sepsis: An updated systematic review of prognostic evidence.
This systematic review assessed the prognostic value of the lactate-to-albumin ratio (LAR) for mortality in adults with sepsis or septic shock.
Outer membrane vesicles in Pseudomonas aeruginosa pathogenesis: a systematic review of virulence dissemination, immune modulation, and antimicrobial resistance, with perspectives for veterinary and one health practice.
This systematic review examines the role of outer membrane vesicles (OMVs) in Pseudomonas aeruginosa pathogenesis, focusing on their virulence, immune modulation, and antimicrobial resistance.
Pharmacokinetics and Target Attainment of Antimicrobial Drugs Throughout Pregnancy. Part II: Cephalosporins.
This systematic review evaluated the pharmacokinetics of cephalosporins in pregnant women, analyzing 44 studies. It found that during the second and third trimesters, the volume of distribution and clearance of these…
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