Trending archive
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497 articles
July 20269
Early-onset lipoprotein glomerulopathy in a 23-month-old boy with homozygous APOE Kyoto variant.
A 23-month-old boy presented with nephrotic syndrome and severe anaemia. A family history of kidney disease, parental consanguinity and enlarged echogenic kidneys on ultrasound prompted early renal biopsy, which showed…
Cribriform Morular Thyroid Carcinoma: Unreported Cytological Features With Histologic Correlation and Diagnostic Lessons From a Case Lacking Morules.
A 29-year-old woman presented with a solitary nodule in the left thyroid lobe, which was solid with microcalcifications on ultrasound.
Divergent Radiomolecular Phenotype of Spindle Cell Lipoma: Intense 68 Ga-PSMA Uptake in a Lesion With Mild 18 F-FDG Avidity.
A 68-year-old man with gastric cancer underwent 18 F-fluorodeoxyglucose (FDG) PET/CT, which revealed an incidental subcutaneous lesion suspicious for low-grade sarcoma or metastasis.
Broncholithiasis mimicking metallic projectiles at autopsy: a forensic diagnostic pitfall in putrefied bodies.
At medico-legal autopsy, a 76-year-old man found in advanced putrefaction had small, hard intrapulmonary nodules that raised suspicion of retained pellets.
Myxoid Variant of Primary Cutaneous Anaplastic Large Cell Lymphoma Mimicking Soft Tissue Sarcoma: Diagnostic Pitfalls and Literature Review.
A 40-year-old man presented with a slowly enlarging ulcerated mass on his left thigh, interpreted radiologically as a superficial soft tissue sarcoma.
Biomarker-Guided Adjuvant Therapy in Stage II/III Colon Cancer: A Systematic Review of Current Evidence and Clinical Implications.
This systematic review synthesised evidence on biomarker-guided adjuvant treatment for resectable stage II/III colon cancer, drawing on 52 studies identified from 1,245 records.
Pleural Effusion Cytology of Metastatic Sclerosing Epithelioid Fibrosarcoma.
A patient presented with a pleural effusion that was found to be metastatic sclerosing epithelioid fibrosarcoma (SEF). Cytological analysis revealed characteristic features of SEF, and immunohistochemistry, particularly…
Case Report: Pancreatic Paraganglioma Mimicking a Well-Differentiated Neuroendocrine Tumor: The Importance of Cytokeratin Immunohistochemistry.
A 79-year-old woman presented with an incidental lesion in the pancreatic head, initially suspected to be a well-differentiated neuroendocrine tumor.
Combined lethal intoxication involving 2-methyl-2-butanol.
The aim was to investigate and clarify the cause of death of a 26-year-old male found dead in his apartment. It was known that the individual used drugs of abuse.
June 202615
Basal Cell Carcinosarcoma with an Osteosarcomatous Component: A Case Report Supporting the Diagnostic Utility of SATB2 and TRAP Immunostaining with a Literature Review of 22 Cases.
A 91-year-old woman presented with a rapidly enlarging solitary tumor on her left cheek, diagnosed as basal cell carcinosarcoma (BCCS) with a focal osteosarcomatous component.
Clinical assessment and diagnostic features of fellatio-associated palatal lesions in forensic sexual abuse investigations: a systematic review.
This PROSPERO-registered systematic review, conducted according to PRISMA 2020 guidelines, examined clinical assessment and diagnostic features of palatal lesions associated with fellatio in forensic sexual abuse…
Laryngeal IgG4-Related Disease: A Systematic Review of Clinical Features and Management.
This systematic review synthesized clinical features, diagnostic approaches, and treatment outcomes in laryngeal IgG4-related disease.
Lipomatous hamartoma of the semilunar valve exhibits molecular genetic characteristics of lipoma.
A 26-year-old woman presented with a symptomatic pulmonary valve lesion initially suspected to be a papillary fibroelastoma. Surgical intervention revealed a lipomatous hamartoma of the pulmonary valve.
Subcutaneous phaeohyphomycosis: ultrasound findings and histopathologic correlation.
A 60-year-old woman presented with a slowly growing subcutaneous nodule. Ultrasound revealed a well-circumscribed hypoechoic pseudocystic lesion with heterogeneous internal echoes and peripheral hypervascularity…
Fibromyxoid Nephrogenic Adenoma Mimicking Renal Cell Carcinoma: A Diagnostic Pitfall in Fine-Needle Aspiration Cytology.
A 72-year-old man presented with a right renal mass, evaluated due to a history of nephrolithiasis. Fine-needle aspiration cytology revealed cloudy red fluid with scant epithelial cells, leading to a pre-operative…
Malignant adenomyoepithelioma of the breast: seven cases illustrating morphological diversity and diagnostic challenges.
This retrospective clinicopathological review describes seven women aged 45–74 years with malignant adenomyoepithelioma (M-AME) of the breast.
Cytological Diagnosis of Primary Cardiac Angiosarcoma Presenting With Multiple Serous Effusions: A Case Report With Cell Block.
A 42-year-old female presented with abdominal distension and exertional dyspnea, leading to the discovery of a cardiac space-occupying lesion and multiple serous effusions.
Myoepithelioma-like tumor of the vulvar region shows a quiet genome and heterogeneous detectable mechanisms of SMARCB1 inactivation: Integrated analysis of two cases and review of the literature.
Two cases of myoepithelioma-like tumor of the vulvar region (MELTVR) were analyzed, characterized by uniform epithelioid to spindle cells in myxoid stroma and complete loss of INI1 expression.
IgG4-related inflammatory pseudotumor presenting with refractory seizures: a diagnostic pitfall.
A patient with a 10-year history of immunoglobulin G4-related disease (IgG4-RD) presented with refractory focal seizures, which later progressed to a tumefactive brain lesion.
STR typing from punched FFPE tissues: resolving suspected contamination and fetal-maternal mixture in two cases.
Two casework applications used targeted punches from formalin-fixed, paraffin-embedded tissue followed by STR profiling. In one, a focus of high-grade urothelial carcinoma in a prostate surgical specimen prompted…
Primary Cutaneous Rosai-Dorfman Disease Presenting as an Infiltrative Dorsal Nasal Mass With Deep Skeletal Muscle Involvement.
A 64-year-old woman had an 18-month history of a progressively enlarging, pruritic mass involving the nasal dorsum and both sidewalls.
Unusual morphologic features in molecularly defined high-grade sarcomas of the uterus.
This report details two cases of high-grade uterine sarcomas with unique genetic alterations. One case featured an FGFR1::TACC1 fusion and exhibited an atypical epithelioid morphology, while the other had an…
Cytological Features of Clear Cell Sarcoma in Exfoliative and Effusion Cytology Specimen-A Case Report and Literature Review.
A patient with metastatic clear cell sarcoma of soft tissue presented with malignant effusions in sputum, peritoneal fluid, and pericardial fluid.
Cytologic Detection of Metastatic Immature Teratomas in Two Young Patients With Unique Presentations.
Two young women presented with high-grade ovarian immature teratomas featuring metastatic immature neuroepithelial components.
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