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1002 articles
August 202617
Pediatric Cluster Headache Beyond Diagnostic Criteria: A Case Series and Review of Treatment Response.
The report describes four children—three boys and one girl—diagnosed with cluster headache, a disorder characterized by brief, unilateral pain around the eye with autonomic symptoms.
Prognostic Accuracy of the Phoenix Sepsis Criteria for Mortality in Children With Suspected Infection: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the prognostic accuracy of the Phoenix Sepsis Criteria (PSC) for in-hospital mortality in children with suspected infections.
Secretory Phospholipase A 2 in Patients With Sickle Cell Disease Hospitalized for Vaso-Occlusive Pain Episodes.
This randomized controlled trial evaluated plasma levels of secretory phospholipase A 2 (sPLA 2) in 105 pediatric patients with sickle cell disease hospitalized for vaso-occlusive pain episodes.
Methodological Quality and Content Analysis of Clinical Practice Guidelines for Fever Management in Children With Sickle Cell Disease.
This systematic review evaluated the methodological quality and content of clinical practice guidelines (CPGs) for managing acute fever in children with sickle cell disease (SCD).
Randomized Placebo-Controlled Trial of Psyllium Fiber in Functional Abdominal Pain Disorders in Children.
This randomized controlled trial evaluated the efficacy of psyllium fiber in children aged 5-18 with functional abdominal pain disorders (FAPD), including IBS and FAP-NOS.
Effects of Virtual Reality Versus Whole-Body Vibration on Muscle Strength and Balance in Children with Duchenne Muscular Dystrophy: a Randomized Controlled Trial.
This assessor-blinded, parallel-group randomized controlled trial compared virtual reality (VR) with whole-body vibration (WBV) as additions to structured physical therapy in 50 ambulatory boys aged 6–10 years with…
The mutual effects on safety and immunogenicity of combined vaccination with 15-valent pneumococcal conjugate vaccine and adsorbed acellular DPT in 3-month healthy infants: A randomized, open-label, controlled, phase III clinical trial.
This phase III randomized controlled trial assessed the safety and immunogenicity of coadministering the 15-valent pneumococcal conjugate vaccine (PCV15) with the DTaP vaccine in 1110 healthy infants aged 3 months.
Clinical Heterogeneity and Long-Term Outcomes of Pediatric Gastrointestinal Stromal Tumors: A Series of Four Patients Highlighting SDH-Deficient and SDH-Intact Subtypes.
This report details four pediatric patients with gastrointestinal stromal tumors (GISTs) over 19 years. Two patients had SDH-deficient tumors, with one experiencing metastatic relapse.
Hypertensive disorders of pregnancy may increase the risk of neurodevelopmental delay in the offspring: a systematic review with meta-analysis.
This systematic review and meta-analysis examined the impact of hypertensive disorders of pregnancy (HDP) on neurodevelopmental delay in offspring.
Pediatric Legionnaires' disease: A case report and a review of the literature.
A 15-month-old girl, previously healthy, developed severe Legionnaires' disease after short-term corticosteroid therapy. The infection was likely acquired in a healthcare setting despite standard water safety measures.
Anterior cingulate cortex alterations in children and adolescents with Attention Deficit and Hyperactivity Disorder: a systematic review of neuroimaging studies.
This systematic review examines neuroimaging studies of the anterior cingulate cortex (ACC) in children and adolescents with Attention-Deficit/Hyperactivity Disorder (ADHD).
ECG challenge: a Kangaroo pitfall.
An apparently irregular rhythm was observed on bedside monitoring in a 32-week preterm infant receiving high-flow nasal cannula support during kangaroo care.
Blinatumomab versus chemotherapy in pediatric B-ALL: A meta-analysis of randomized trials in relapsed and high-risk frontline disease.
This meta-analysis evaluated the efficacy of blinatumomab compared to chemotherapy in pediatric patients with relapsed/refractory or high-risk frontline B-cell acute lymphoblastic leukemia (B-ALL).
Pediatric tularemia in Denmark: a forgotten disease.
Two pediatric patients in Denmark presented with persistent fever, an eschar, and inguinal lymphadenitis, initially misdiagnosed as a common bacterial infection.
Empathic Communication in Pediatric Palliative Care: A Mixed-Methods Systematic Review.
This mixed-methods systematic review synthesized evidence on empathic communication between healthcare providers and parents in pediatric palliative care. It included 54 studies with approximately 3567 participants.
Gastrointestinal Adverse Events Following Rotavirus Vaccination in Children: A Systematic Review.
This systematic review assessed gastrointestinal adverse events after RV1 and RV5 rotavirus vaccination in children, drawing on randomised trials, meta-analyses, and case reports published from 2007 onwards.
Empowered Relief for Youth: Development, feasibility and early effectiveness of a single session pain relief skills class.
This single-arm clinical trial adapted Empowered Relief, a one-session pain-management class, for youth with chronic pain and assessed feasibility, acceptability, and preliminary outcomes.
July 20267
Clinical, Histopathological, and Molecular Characterization of Pediatric MN1::ZNF341-Associated Cancer.
A lethal round-cell malignancy with an MN1::ZNF341 fusion has recently been reported in three infants. Here, we describe four further tumors, three in newborns (including monozygotic twins), and one in an adolescent.
Smoking cessation interventions for parents of children with chronic disease: A systematic review and meta-analysis of randomised controlled trials.
This systematic review and meta-analysis evaluated smoking cessation interventions for parents of children with chronic diseases, analyzing ten randomized controlled trials with 3758 participants.
Precision of neuromuscular monitoring in paediatric patients: a randomised prospective agreement study of kinemyography and electromyography.
This randomized controlled trial evaluated the precision of kinemyography versus electromyography for neuromuscular monitoring in children under 5 years old.
Recurrent KCNN4 p.Ser314Pro variant in a child with Gardos channelopathy: a 6-year follow-up.
A child with Gardos channelopathy due to a recurrent KCNN4 p.Ser314Pro variant was followed for 6 years. The patient maintained a stable baseline but experienced hemolytic crises triggered by infections and exacerbated…
Association of maternal prepregnancy malnutrition with offspring growth trajectories: a secondary data analysis of the Women First Trial.
This secondary data analysis from the Women First Trial examined the impact of maternal prepregnancy malnutrition on offspring growth in 2228 mother-child pairs across several countries.
Clinical Reasoning: A Toddler With Heat Stroke.
A 17-month-old boy presented with febrile seizures and encephalopathy after being exposed to hot weather in a poorly ventilated car.
Dexamethasone-Free Antiemetic Prophylaxis for Children and Adolescents Receiving Highly Emetogenic Chemotherapy: A Multicenter, Phase III, Noninferiority Trial (CIVIC POD).
The CIVIC POD trial evaluated the efficacy of olanzapine versus dexamethasone for preventing chemotherapy-induced nausea and vomiting in children aged 4-18 receiving highly emetogenic chemotherapy.
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