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1002 articles
October 202624
Neurosurgical manifestations and management of mucopolysaccharidoses: A systematic review.
This PRISMA-guided systematic review synthesized contemporary reports of neurosurgical manifestations and management across mucopolysaccharidosis (MPS) subtypes.
Neonatal gastric perforation: a systematic review and meta-analysis of clinical characteristics, risk factors, surgical management and outcomes.
This systematic review and meta-analysis examined clinical features, risk factors, surgical management and outcomes of neonatal gastric perforation using observational studies of neonates aged 28 days or younger.
Ciliated hepatic foregut cyst in children and adolescents: a systematic review of clinical presentation, diagnosis, management, and outcomes.
This PRISMA 2020 systematic review descriptively synthesised case reports and case series of histopathologically confirmed ciliated hepatic foregut cysts in patients aged 19 years or younger.
Phenotypic variability in Arboleda-Tham syndrome: a report of a polish patient with a pathogenic KAT6A variant.
A 6-year-old boy born to healthy parents had global developmental delay, with milestones reached substantially later than expected. Diagnostic evaluation began at 18 months.
The effect of seizure-free period on seizure recurrence following antiseizure medication withdrawal: a systematic review and meta-analysis.
This systematic review and random-effects meta-analysis examined whether the duration of seizure freedom before antiseizure medication (ASM) withdrawal is associated with subsequent seizure recurrence in people with…
Cochlear Implantation in a Child With Arnold-Chiari Syndrome, Severe Inner Ear Malformations, and Cochlear Nerve Hypoplasia: A Case Report.
A 1.5-year-old girl with Arnold-Chiari malformation, hydrocephalus, spina bifida, and profound bilateral sensorineural hearing loss had limited auditory development despite early hearing-aid use.
Oxygen vs Air at Birth for Moderate- to Late-Preterm Infants: The AIROPLANE Cluster Randomized Crossover Trial.
The AIROPLANE trial was an unblinded, cluster randomized crossover study at 26 Australian maternity hospitals comparing initial oxygen concentrations of 0.30 and 0.21 during the first 3 minutes of respiratory support…
The impact of recreational beach tennis associated with nutritional counseling on cardiometabolic risk factors in adolescents: a randomized clinical trial.
This 12-week randomized clinical trial compared recreational beach tennis alone with beach tennis plus nutritional counseling in 40 adolescents aged 11–14 years.
Pacak-Zhuang syndrome with EPAS1 p.Pro531Leu somatic variant: one case report and literature review.
A 4-year-old girl presented with recurrent hypertension, polycythemia and renal hilar masses. Imaging, biochemical testing and genetic analysis of paraffin-embedded tissue confirmed Pacak-Zhuang syndrome with a somatic…
High-Resolution Ultrasound in the Evaluation of Median and Superficial Radial Nerve Involvement in Neurofibromatosis Type 1.
A 16-year-old girl with neurofibromatosis type 1 presented with hand pain and paresthesia. High-resolution ultrasound showed a hypervascular superficial neurofibroma, marked epineural thickening of the median nerve…
Paediatric Helicobacter pylori infection and allergic and inflammatory diseases: a contemporary systematic review with meta-analysis.
This systematic review and meta-analysis assessed recent evidence on Helicobacter pylori infection and allergic or immune-mediated diseases in children.
Clinical and functional outcomes of aquatic plyometrics in adolescent patellofemoral pain syndrome: a dual-arm randomized controlled trial.
This dual-arm randomized controlled trial compared aquatic plyometric exercises with conventional exercises in 56 adolescents aged 10–18 years with patellofemoral pain syndrome.
Comparable efficacy of extraoral and intraoral photobiomodulation in preventing oral mucositis during high-dose methotrexate therapy in pediatric oncology: A single-blind randomized controlled trial.
This single-blind randomized controlled trial compared intraoral (IO) with extraoral (EO) photobiomodulation (PBM) to prevent oral mucositis in 155 children and adolescents receiving high-dose methotrexate for leukemia…
Effectiveness of digital educational technologies in knowledge acquisition for adolescent health promotion: a systematic review.
This systematic review assessed whether digital educational technologies improve health-promotion knowledge among adolescents.
An Integrated Approach to MSI-High Colorectal Cancer Therapy in a Young Patient: A Clinical Case.
A 16-year-old male underwent appendectomy for presumed appendicitis, but persistent postoperative bowel obstruction led to CT detection of a descending-colon tumor and emergency Hartmann’s procedure.
Switching from Intravenous to Subcutaneous Infliximab in Children with Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis synthesized six independent, largely observational cohorts of children with inflammatory bowel disease who switched from intravenous to subcutaneous infliximab (n = 173).
Pulpotomy of deciduous molars with deep caries using three different hydraulic calcium silicate cements: a short-term pilot randomized controlled split-mouth study.
This short-term pilot randomized controlled split-mouth study compared three hydraulic calcium silicate cements for pulpotomy in carious primary molars of children aged 2–6 years treated under general anesthesia.
The Impact of Ambient Ozone Exposure on Respiratory Health in the U.S. Populations: A Systematic Review.
This systematic review synthesized U.S. epidemiologic and experimental studies published from 1980 to 2026 on acute and chronic ambient ozone exposure and respiratory health.
Sleep apnea-hypopnea in children: Evidence that Lize Tongqi decoction with acupuncture, moxibustion, and Xinwu acupoint stimulation is superior to standard Western treatment using montelucast/mometasone furoate.
This randomized controlled trial compared a combined traditional Chinese medicine and acupuncture-based regimen with montelukast plus mometasone in 60 children with snoring (mean age 7.9 years).
Cardiac arrest in an adolescent following an overdose of antidepressants comprising sertraline, quetiapine fumarate, and lamotrigine: Case report.
An 11-year-old with depression ingested large quantities of sertraline (3 g), quetiapine fumarate (5 g), and lamotrigine (3 g).
A novel de novo variant of CDKL5 in an Iranian child with infantile-onset refractory epilepsy.
An Iranian girl presented with developmental delay, hypotonia, and refractory seizures. Whole-exome sequencing identified a de novo CDKL5 frameshift variant, c.1037_1038delTCinsCAGATCTAA (p.Ile346Thrfs*14), which Sanger…
A case of neonatal gastric perforation misdiagnosed as neonatal necrotizing enterocolitis: A literature review.
A male infant born at 33 weeks and 5 days presented on day four of life with abdominal distension, feeding refusal, and no passage of flatus or stool.
Infant hippocampal and amygdala volume in an observational follow-up from a randomized clinical trial for maternal prenatal depression.
This observational follow-up examined brain volumes and later negative emotionality in 109 infants born to mothers who had participated in a randomized clinical trial of brief interpersonal psychotherapy for prenatal…
Predicting neurodevelopmental delay among two-year-old infants in Northern Uganda.
This study developed and evaluated a risk-prediction model for neurodevelopmental delay among two-year-old children in Northern Uganda.
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