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785 articles

June 202619

Clinical ResearchGastroenterologyOpen access

Endoscopic Ultrasound-Guided Versus Transjugular Portal Pressure Measurements: Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated the correlation between endoscopic ultrasound-guided portal pressure gradient (EUS-PPG) and invasive hemodynamic measurements in six prospective cohorts.

Dig Dis SciJun 5, 2026Read summary
Clinical ResearchOncology (Medical)

Efficacy and Safety of Pembrolizumab in Advanced Gastric Cancer: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated the efficacy and safety of pembrolizumab in 4,560 patients with advanced gastric cancer.

Cancer InvestJun 5, 2026Read summary
Clinical ResearchGastroenterology

Complementary use of white-light endoscopy and narrow-band imaging for postendoscopic mucosal resection scar assessment: a systematic review and diagnostic meta-analysis.

This systematic review and diagnostic meta-analysis assessed white-light endoscopy (WLE) and narrow-band imaging (NBI) for detecting recurrence at colorectal endoscopic mucosal resection (EMR) scars during surveillance…

Gastrointest EndoscJun 5, 2026Read summary
Clinical ResearchGastroenterology

Impact of Availability of Computer-Aided Detection Devices on Adenoma Detection During Colonoscopy: A Cluster Randomized Study.

This pragmatic, multicentre cluster-randomised quality improvement study assessed whether making computer-aided detection (CADe) devices available affected adenoma detection during colonoscopy at Veterans Health…

GastroenterologyJun 5, 2026Read summary
Clinical ResearchGastroenterology

The role of exosomal microRNAs in detecting hepatocellular carcinoma: A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the diagnostic performance of exosomal microRNAs (miRNAs) in detecting hepatocellular carcinoma (HCC) among 1442 HCC patients, 761 healthy controls, and 1091 chronic…

Clin Chim ActaJun 4, 2026Read summary
Clinical ResearchGastroenterology

Late hiatal hernia after Roux-en-Y gastric bypass: a systematic review.

This systematic review examined late hiatal hernia (HH) after Roux-en-Y gastric bypass (RYGB) in patients with obesity. The study found that HH is associated with gastroesophageal reflux disease (GERD) in 39-93.6% of…

Surg Obes Relat DisJun 4, 2026Read summary
Case ReportGastroenterology

Severe cytomegalovirus gastritis and hypogammaglobulinemia in a patient treated with pembrolizumab.

A 66-year-old man with stage IVB oesophageal carcinoma, treated with pembrolizumab, presented with gastric erosions and ulcers.

Eur J Gastroenterol HepatolJun 3, 2026Read case
Clinical ResearchEndocrinology

Evenly Distributing Daily Dietary Protein Across Three Meals Reduces Women's Snack Food Reinforcement and Intake of Energy-Dense Snack Foods During Weight Loss: A Randomized Controlled Trial.

This randomized controlled trial examined the impact of protein distribution on snack food reinforcement and intake among healthy women aged 20 to 44 with a BMI of 28 to 45.

J Acad Nutr DietJun 3, 2026Read summary
Clinical ResearchGastroenterology

Learning and deskilling effects of artificial intelligence in colonoscopy among endoscopists with different levels of experience: a pragmatic, prospective trial.

This pragmatic, multicenter trial evaluated the impact of computer-aided detection (CADe) on polyp detection rates (PDR-5) among 13 endoscopists with varying experience levels.

EndoscopyJun 3, 2026Read summary
Clinical ResearchGastroenterologyOpen access

Rotational thromboelastometry versus conventional tests in decompensated cirrhotic children undergoing invasive procedures.

This randomized controlled trial evaluated the efficacy of a ROTEM-guided transfusion strategy in children aged 6 months to 18 years with decompensated cirrhosis undergoing invasive procedures.

J Pediatr Gastroenterol NutrJun 3, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Prognostic Value of Circulating Tumor DNA-Based Minimal Residual Disease for Recurrence-Free Survival in Resectable Gastric Cancer: A Systematic Review and Meta-Analysis with Serial Monitoring Analysis.

This systematic review and meta-analysis evaluated the prognostic value of circulating tumor DNA (ctDNA)-based minimal residual disease (MRD) in 520 patients with resectable gastric cancer.

Dig Dis SciJun 3, 2026Read summary
Clinical ResearchGastroenterology

A phase 1 study to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of PF-07261271 in healthy participants.

This phase 1 randomized controlled trial evaluated the safety, tolerability, pharmacokinetics, and pharmacodynamics of PF-07261271, a bispecific antibody, in 35 healthy participants.

Br J Clin PharmacolJun 3, 2026Read summary
Clinical ResearchOncology (Medical)

Gut microbiome dysbiosis and cancer: A systematic review on the emerging role of probiotics in oncology.

This systematic review evaluated the impact of probiotic supplementation in cancer patients, focusing on its clinical effects.

Crit Rev Oncol HematolJun 2, 2026Read summary
Case ReportGastroenterology

Sudden Acute Liver Failure in Citrullinemia Type 1: An Argument for Earlier Liver Transplantation?

This report details a case of a child with citrullinemia type 1 who presented with sudden acute liver failure. Despite medical management, the child experienced recurrent hepatic decompensations, ultimately…

J PediatrJun 2, 2026Read case
Clinical ResearchGastroenterology

Rule-Out Cutoff of Two-Dimensional Shear Wave Elastography for Significant Fibrosis in Metabolic Dysfunction-Associated Steatotic Liver Disease: Systematic Review, Meta-Analysis, and External Validation.

This systematic review and meta-analysis evaluated the diagnostic performance of two-dimensional shear-wave elastography for detecting significant fibrosis (≥F2) in 3171 adults with metabolic dysfunction-associated…

Clin Gastroenterol HepatolJun 2, 2026Read summary
Clinical ResearchGastroenterologyOpen access

Randomized Trial of Intensive Nurse-Led Follow‑Up Versus Standard Care in Inflammatory Bowel Disease.

This randomized controlled trial assessed the impact of an intensive nurse-led follow-up program on patients with inflammatory bowel disease (IBD) starting advanced therapy.

Dig Dis SciJun 2, 2026Read summary
Clinical ResearchGastroenterology

Endoscopic ultrasound-guided gastroenterostomy vs surgical gastrojejunostomy for malignant gastric outlet obstruction: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated endoscopic ultrasound-guided gastroenterostomy (EUS-GE) versus surgical gastrojejunostomy (SGJ) for malignant gastric outlet obstruction in 22,118 patients.

J Gastrointest SurgJun 1, 2026Read summary
Clinical ResearchGastroenterology

Top-down versus step-up approach after endoscopic ultrasound-guided drainage of infected walled-off necrosis: a randomized controlled trial.

This randomized controlled trial compared top-down versus step-up approaches after endoscopic ultrasound-guided drainage of infected walled-off necrosis in 54 patients.

EndoscopyJun 1, 2026Read summary
Clinical ResearchGastroenterologyOpen access

Feasibility and efficacy of fecal microbiota transplantation in adolescents with refractory irritable bowel syndrome: A randomized clinical pilot trial.

This randomized controlled pilot trial evaluated the feasibility and efficacy of fecal microbiota transplantation (FMT) in 32 adolescents aged 16-21 with refractory irritable bowel syndrome (IBS).

J Pediatr Gastroenterol NutrJun 1, 2026Read summary

May 20265

Clinical ResearchGastroenterology

Theories and determinants of self-care and self-efficacy in inflammatory bowel diseases: A systematic review.

This systematic review evaluated theories and determinants of self-care and self-efficacy in patients with inflammatory bowel disease (IBD).

Patient Educ CounsMay 31, 2026Read summary
Case ReportGastroenterology

Contrast-Enhanced Ultrasound Successfully Diagnoses a Rare Case of Coexisting Colorectal Cancer Liver Metastasis and Hepatocellular Carcinoma: A Case Report.

A 57-year-old Asian male presented with a rectal mass and multiple distinct liver lesions. Contrast-enhanced ultrasound (CEUS) suggested the presence of both colorectal cancer liver metastasis and hepatocellular…

J Clin UltrasoundMay 31, 2026Read case
Clinical ResearchRadiology (Diagnostic)Open access

Comparison of abbreviated MRI and ultrasonography in the detection of early hepatocellular carcinoma: a meta-analysis.

This meta-analysis compared abbreviated magnetic resonance imaging (AMRI) with ultrasonography (US) for detecting early-stage hepatocellular carcinoma. Nine studies involving 1,914 participants were included.

Clin Transl OncolMay 31, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Pilot Randomized Trial of a Supportive Care Intervention for Patients With Locally Advanced Rectal Cancer.

This pilot randomized controlled trial evaluated the feasibility and acceptability of the PATHWAYS supportive care intervention for patients starting multimodality therapy for locally advanced rectal cancer (LARC).

J Pain Symptom ManageMay 30, 2026Read summary
Case ReportGastroenterology

Fascioliasis presenting as non-resolving liver abscess: Case series from eastern India.

A series of six cases of fascioliasis were identified in eastern India, where patients presented with acute symptoms including fever and abdominal pain.

Trop DoctMay 30, 2026Read case

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