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755 articles
May 20262
Postural Instability Is Greater in Men with Type 2 Diabetes after Exertional Heat Stress.
This randomized controlled trial investigated the effects of exertional heat stress on postural stability in middle-aged men with and without type 2 diabetes (T2D).
Effectiveness and Safety of Setmelanotide in a Patient With a Heterozygous PCSK1 Deficiency.
A 40-year-old female with a heterozygous PCSK1 N221D variant presented with severe early-onset treatment-resistant obesity.
April 202622
Acute metabolic responses to breaking up sedentary time in older adults.
This randomized controlled trial examined the effects of interrupting sedentary time with light activity on metabolic flexibility in 12 sedentary older adults.
Efficacy and safety of Mudan granules for treatment of diabetic peripheral neuropathy: a multicenter, double-blind, placebo-controlled, randomized, clinical trial.
This multicenter, double-blind, placebo-controlled randomized trial evaluated the efficacy and safety of Mudan granules in 400 patients with diabetic peripheral neuropathy (DPN).
68 Ga-Trivehexin PET/CT Revealing Concomitant Papillary Thyroid Carcinoma and Parathyroid Adenoma.
A patient diagnosed with papillary thyroid carcinoma underwent preoperative imaging using 68 Ga-Trivehexin PET/CT. The imaging revealed not only the thyroid malignancy but also a concomitant parathyroid adenoma.
Metabolic Effects of Modified-Release Hydrocortisone Versus Short Acting Conventional Oral Glucocorticoids in Adrenal Insufficiency: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the metabolic effects of modified-release hydrocortisone (MR-HC) compared to conventional glucocorticoids in patients with adrenal insufficiency.
Neonatal and obstetric outcomes following periconceptional exposure to glucagon-like peptide-1 receptor agonists: a systematic review and meta-analysis.
To evaluate the association between periconceptional exposure to glucagon-like peptide-1 receptor agonists and fetal, pregnancy-related, obstetric, and delivery outcomes.
Effects of Weight Loss Interventions on Gut Microbiota-Derived Metabolites Linked to Cardiometabolic Health: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed how weight-loss interventions affect circulating gut microbiota-derived metabolites in people with overweight or obesity.
The Effect of Behavioral Sleep Interventions on Measures of Obesity, Dietary Intake and Physical Activity in Adults With Poor Sleep Health: A Systematic Review, Meta-Analysis and Meta-Regression Analysis.
This systematic review and meta-analysis examined whether sleep interventions improve obesity-related measures, dietary intake, or physical activity in adults with poor sleep health and without obstructive sleep apnoea.
Efficacy of Exercise-Based Interventions for Metabolic Syndrome: An Umbrella Review With Meta-Analyses.
This umbrella review with meta-analyses assessed exercise-based interventions for metabolic syndrome (MetS), synthesizing 12 systematic reviews covering 122 primary studies and 9639 participants.
The effect of the healthy lifestyle 'empowerment program' on care burden and adherence to health-promoting behaviours on mothers of children with type 1 diabetes.
This randomized controlled trial assessed the Healthy Lifestyle Empowerment Program (HLEP) for mothers of children with type 1 diabetes (T1D) in Tehran.
Exploring the role of successful exercise-induced body weight loss on cardiometabolic health in individuals with metabolic syndrome.
This randomized controlled trial investigated the impact of high-intensity interval training (HIIT) on cardiometabolic health in 228 adults with metabolic syndrome.
Effects of UDCA and probiotics on metabolic outcomes in type 2 diabetes patients on metformin: A randomized trial in Bosnia and Herzegovina.
This randomized controlled trial evaluated the effects of probiotics and ursodeoxycholic acid (UDCA) on metabolic outcomes in 90 metformin-treated patients with type 2 diabetes (T2D) over four weeks.
A randomized controlled trial on the effect of Gushukang on bone mineral density in perimenopausal and postmenopausal women.
This randomized controlled trial investigated the effects of Gushukang on bone mineral density (BMD) in 156 perimenopausal and postmenopausal women.
Calorie-restricted oat diet is associated with zonulin and short-chain fatty acid response in metabolic syndrome: a randomized controlled trial.
This randomized controlled trial examined the effects of two oat diets on gut permeability markers in individuals with metabolic syndrome.
Neuroendocrine signature of ME/CFS: Meta-analytic evidence for bioactive cortisol deficit and exaggerated feedback sensitivity.
This meta-analysis examined the neuroendocrine profile of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) by analyzing 46 studies with 1388 patients.
Electronic alert-based computerized decision support for detection of chronic kidney disease in type 2 diabetes mellitus: CKD-DETECT.
The CKD-DETECT randomized controlled trial evaluated an electronic alert system for urine albumin-to-creatinine ratio (UACR) testing in outpatients with type 2 diabetes.
Cost-effectiveness of tirzepatide versus semaglutide for patients with obesity or overweight in the US: evidence from the SURMOUNT-5 head-to-head phase-3 trial.
This study assessed the cost-effectiveness of tirzepatide versus semaglutide in adults with obesity or overweight in the US, using data from the Phase-3 SURMOUNT-5 trial.
The effect of low-carbohydrate diets on serum concentration of soluble adhesion molecules: a systematic review and meta-analysis of randomized controlled trials.
This systematic review and meta-analysis evaluated the impact of low-carbohydrate diets (LCDs) on serum levels of adhesion molecules in adults.
Ultrasound Diagnosis of Giant Testicular Adrenal Residual Tumors: A Case Report and Literature Review.
A 9-year-old male with congenital adrenal hyperplasia presented with giant testicular adrenal residual tumors (TARTs) associated with 11β-hydroxylase deficiency.
Emerging Effects of Glucagon-Like Peptide-1 Receptor Agonists and Sodium-Glucose Cotransporter 2 Inhibitors on Male Sexual Hormones and Behaviors: Systematic Review and Meta-Analysis.
This systematic review and meta-analysis examined the effects of glucagon-like peptide-1 receptor agonists (GLP1-RAs) and sodium-glucose cotransporter 2 inhibitors (SGLT2is) on male sexual hormones and function in…
Patient Preferences, Perceptions, and Influencing Factors in Weight Loss Pharmacotherapy and Bariatric Surgery: A Systematic Literature Review.
This systematic review analyzed patient preferences regarding weight loss pharmacotherapy and bariatric surgery among adults with overweight or obesity.
Comparative evaluation of oxidative stress biomarkers F2-isoprostanes and 8-OHdG in Parkinson's disease and Type 2 Diabetes Mellitus: a systematic review and meta-analysis of human studies.
This systematic review and meta-analysis evaluated oxidative stress biomarkers F2-isoprostanes and 8-OHdG in individuals aged ≥ 50 years with Type 2 Diabetes Mellitus (T2DM) and Parkinson's Disease (PD).
Acute-onset autoimmune type 1 diabetes presenting with diabetic ketoacidosis in an obese adult.
A 51-year-old obese man presented with severe diabetic ketoacidosis, characterized by hyperglycemia of 1297 mg/dL and metabolic acidosis.
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