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441 articles

September 202624

Clinical ResearchGeriatrics

A high intensity vs. casual speed walking intervention to reverse frailty among older adults: a cluster randomized controlled trial.

This cluster-randomized controlled trial evaluated the effects of high-intensity walking (HIW) versus casual-speed walking (CSW) on frailty in 165 prefrail and frail adults aged ≥60 years.

PLoS OneSep 30, 2026Read summary
Clinical ResearchGeriatricsOpen access

Does baseline physical function modify the response to a physical activity intervention in adults with arthritis? A secondary analysis of a randomized trial.

This secondary analysis of a randomized controlled trial examined whether baseline physical function influenced the response to a telephone-delivered Walk With Ease (WWE-T) intervention in 267 adults with arthritis.

Rheumatol IntSep 30, 2026Read summary
Clinical ResearchAnesthesiologyOpen access

Effect of early regional anesthesia on postoperative cognitive function and the perioperative stress response in patients with hip fractures: a randomized controlled trial.

This randomized controlled trial investigated the effect of anterior iliopsoas muscle space block (AIMSB) timing on postoperative delirium (POD) in 79 elderly patients undergoing total hip arthroplasty for fractures.

PeerJSep 30, 2026Read summary
Clinical ResearchEndocrinology

Sarcopenia in Indian adults with type 2 diabetes: a systematic review and meta-analysis of prevalence and associated factors.

This systematic review and meta-analysis assessed the prevalence of sarcopenia among Indian adults with type 2 diabetes mellitus (T2DM).

BMJ OpenSep 29, 2026Read summary
Case ReportPsychiatry

Recurrent serotonin syndrome during low-dose venlafaxine treatment in a patient with reduced CYP2D6 activity.

A man in his late 70s with transthyretin amyloidosis experienced recurrent serotonin syndrome while on low-dose venlafaxine treatment.

BMJ Case RepSep 29, 2026Read case
Clinical ResearchNeurologyOpen access

Efficacy of transcranial alternating current stimulation on cognitive function in patients with dementia: a systematic review and meta-analysis of randomized controlled trials.

This systematic review and meta-analysis evaluated the efficacy of transcranial alternating current stimulation (tACS) on cognitive function in 357 dementia patients across 9 randomized controlled trials.

Neurol SciSep 29, 2026Read summary
Clinical ResearchGeriatricsOpen access

Dual Sensory Impairment and Depressive Symptoms: Association and Pathways in Three Cohorts and a Meta-Analysis.

This meta-analysis examined the relationship between dual sensory impairment (DSI) and depressive symptoms in three aging cohorts: CHARLS, HRS, and ELSA.

Depress AnxietySep 29, 2026Read summary
Clinical ResearchGeriatrics

A study protocol evaluating the effectiveness of the older adult's digital health literacy (ODDHeaL) intervention.

This randomized controlled trial evaluates the effectiveness of the Older Adults Digital Health Literacy (ODDHeaL) intervention in improving digital health literacy among community-dwelling adults aged 55 and older.

PLoS OneSep 28, 2026Read summary
Clinical ResearchGeriatrics

Healthcare spending and factors associated with fall injury in Australia residential aged care: a cohort analysis.

This cohort analysis examined healthcare spending and factors associated with fall injuries in Australian residential aged care, utilizing data from the Opti-Med trial involving 303 participants aged ≥65 years.

Inj PrevSep 28, 2026Read summary
Case ReportGeriatrics

Electrical Impedance Tomography-Guided Precision Nursing in an Older Patient With Septic Shock and ARDS: A Case Report.

A 79-year-old patient with septic shock, ARDS, and MODS underwent precision nursing management utilizing electrical impedance tomography (EIT).

Nurs Crit CareSep 26, 2026Read case
Clinical ResearchGeriatrics

Does Dosage Drive Durability? A Longitudinal Study on Digital Cognitive Training for Sustained Functional Independence.

This randomized controlled trial examined the effects of digital cognitive training (DCT) on cognition and functionality in older adults with Mild Neurocognitive Disorder.

Geriatr Gerontol IntSep 26, 2026Read summary
Clinical ResearchGeneral SurgeryOpen access

Robotic versus laparoscopic surgery in older adults: a systematic review and meta-analysis of recovery-centered outcomes.

This systematic review and meta-analysis evaluated recovery-centered outcomes of robotic versus laparoscopic surgery in older adults, analyzing 41 observational studies.

J Robot SurgSep 26, 2026Read summary
Clinical ResearchGeriatrics

Effect of Multi-Modal Training in Patients With Mild Cognitive Impairment: A Randomized Controlled Pilot Trial.

This pilot randomized controlled trial evaluated the effects of a 24-week multi-modal training program on cognitive function in 65 older adults with mild cognitive impairment (MCI).

Med Sci MonitSep 26, 2026Read summary
Case ReportHematology

When A Fall Isn't Just a Fall: Delayed Diagnosis of Acquired Hemophilia A in a Nonagenarian Patient.

A 92-year-old woman presented with severe right lower extremity pain after recurrent ground-level falls. Imaging revealed bilateral lower extremity intramuscular hematomas.

Am J Case RepSep 26, 2026Read case
Clinical ResearchOncology (Medical)

Sarcopenia Is Associated With Severe Treatment Toxicity and Mortality in Older Adults With Advanced Cancer: A Secondary Analysis.

This secondary analysis of a randomized controlled trial examined the impact of sarcopenia on treatment outcomes in 161 older adults (≥ 70 years) with advanced cancer.

J Cachexia Sarcopenia MuscleSep 25, 2026Read summary
Clinical ResearchGeriatrics

Study on blueberries, protein and exercise for improving frailty and cardiovascular disease (STRONG): protocol for a parallel-group randomised controlled superiority trial in older Nova Scotians.

The STRONG study is a parallel-group randomized controlled trial aimed at assessing the impact of a year-long intervention involving blueberries, protein, and exercise on frailty and cardiovascular health in 240 older…

BMJ OpenSep 25, 2026Read summary
Clinical ResearchGeriatrics

Nonlinear dose-response of mind-body exercise in older adults with mild cognitive impairment: A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the dose-response relationship of mind-body exercise on cognitive function in older adults with mild cognitive impairment (MCI).

PLoS OneSep 25, 2026Read summary
Clinical ResearchNeurology

Wearable Sensors in Gait Assessment for Parkinson Disease and Stroke in Real-World Environments: Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated the use of wearable sensors for gait assessment in patients with Parkinson disease (PD) and stroke. It included 43 studies, primarily focusing on PD (2774 participants).

J Med Internet ResSep 25, 2026Read summary
Clinical ResearchGeriatrics

Systematic review and meta-analysis of biomarkers of sarcopenia and sarcopenic obesity.

This systematic review and meta-analysis examined the associations between biomarkers and sarcopenia/sarcopenic obesity (SO) in various populations.

Medicine (Baltimore)Sep 25, 2026Read summary
Clinical ResearchGeriatrics

Comparative efficacy of various non-pharmacological therapies on cognitive function in patients with mild cognitive impairment or dementia: A network meta-analysis.

This network meta-analysis evaluated the efficacy of non-pharmacological therapies on cognitive function in 2082 patients with mild cognitive impairment or dementia.

Medicine (Baltimore)Sep 25, 2026Read summary
Clinical ResearchGeriatrics

Associations Between Gut Microbiota and Immune Profiles in Community-Dwelling Older Adults and the Regulatory Role of Polygonatum odoratum.

This randomized controlled trial investigated the effects of Polygonatum odoratum on gut microbiota and immune profiles in 140 community-dwelling older adults aged 60 and above over 90 days.

Aging CellSep 24, 2026Read summary
Clinical ResearchGeriatrics

Bridging the gap in caregiver support: A systematic review of screening practices in primary care.

This systematic review examined the use of caregiver burden screening practices in primary care, focusing on studies from 2013 to 2023.

Nurse PractSep 24, 2026Read summary
Case ReportOrthopedic Surgery

Awake full-endoscopic transforaminal lumbar interbody fusion via the trans-Kambin approach under local anaesthesia in a nonagenarian.

A nonagenarian with recurrent symptomatic foraminal stenosis at L4-L5, following previous decompression surgeries, underwent full-endoscopic transforaminal lumbar interbody fusion (FE-TLIF) via the trans-Kambin approach…

BMJ Case RepSep 24, 2026Read case
Clinical ResearchCardiology

Survival benefit of guideline-directed medical therapy in older patients with heart failure: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the survival benefits of guideline-directed medical therapy (GDMT) in older patients (≥65 years) with heart failure and reduced ejection fraction (HFrEF).

HeartSep 24, 2026Read summary

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