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434 articles

October 202612

Clinical ResearchPulmonology

Pulmonary specialist health coach consultation model: a randomized controlled trial.

This randomized controlled trial evaluated a pulmonary specialist health coach consultation model for low-income patients with asthma and/or COPD.

Ann Am Thorac SocOct 1, 2026Read summary
Clinical ResearchPediatricsOpen access

Early-life liquefied petroleum gas cooking intervention and lung function in Guatemalan children: a randomized clinical trial.

This randomized clinical trial assessed the impact of an early-life liquefied petroleum gas cooking intervention on lung function in Guatemalan children.

Ann Am Thorac SocOct 1, 2026Read summary
Clinical ResearchPsychiatry

Quetiapine modestly improves sleep and breathing but impairs next-day performance in people with obstructive sleep apnea and difficulty maintaining sleep: a randomized controlled trial.

This randomized controlled trial evaluated the effects of 50 mg quetiapine versus placebo in 15 individuals with obstructive sleep apnea (OSA) and difficulty maintaining sleep.

Ann Am Thorac SocOct 1, 2026Read summary
Clinical ResearchPulmonology

Effects of high-dose supplemental oxygen therapy on pulmonary haemodynamics at 3250 m in high-altitude residents at risk for pulmonary hypertension.

This open-label, non-randomised trial investigated the effects of high-dose supplemental oxygen therapy (SOT) on pulmonary haemodynamics in Kyrgyz highlanders at 3250 m with elevated systolic pulmonary artery pressure…

BMJ Open Respir ResOct 1, 2026Read summary
Clinical ResearchOncology (Medical)

Toripalimab consolidation after chemoradiotherapy in limited-stage small cell lung cancer: a phase II, randomized controlled study (GASTO-1052A).

This phase II randomized controlled trial evaluated the efficacy and safety of toripalimab consolidation after chemoradiotherapy in patients with limited-stage small cell lung cancer (LS-SCLC).

J Immunother CancerOct 1, 2026Read summary
Clinical ResearchHematology

Management of Antineutrophil Cytoplasmic Antibody-Associated Alveolar Hemorrhage: A Bayesian Reanalysis of the PEXIVAS Trial.

This Bayesian reanalysis of the PEXIVAS trial focused on adults with antineutrophil cytoplasmic antibody-associated vasculitis and diffuse alveolar hemorrhage (DAH).

J RheumatolOct 1, 2026Read summary
Clinical ResearchInfectious Diseases

HIV-associated pulmonary arterial hypertension: improving survival despite persistent treatment gaps - a systematic review and meta-analysis.

This systematic review and meta-analysis examined 12 cohorts of patients with HIV-associated pulmonary arterial hypertension (HIV-PAH), totaling 537 individuals.

AIDSOct 1, 2026Read summary
Clinical ResearchInfectious DiseasesOpen access

Evaluating plasma ferritin and suPAR as treatable traits for critically ill patients with COVID-19 treated with anakinra: an exploratory analysis of the immune modulation domain of the REMAP-CAP randomised clinical trial.

This exploratory analysis of the REMAP-CAP randomized clinical trial evaluated plasma ferritin and suPAR as potential treatable traits for anakinra in critically ill COVID-19 patients.

Crit CareOct 1, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Health Communication and Stepped Reminders Interventions for Lung Cancer Screening: A Randomized Clinical Trial.

This randomized clinical trial evaluated two patient-centered interventions aimed at increasing adherence to annual lung cancer screening among patients with normal findings.

JAMA Intern MedOct 1, 2026Read summary
Clinical ResearchPulmonologyOpen access

Autonomous Oxygen Titration for Maintaining Normoxemia in Acutely Ill Adults: The SAVE-O2 AI Randomized Clinical Trial.

The SAVE-O2 AI randomized clinical trial evaluated the effectiveness of autonomous oxygen titration in maintaining normoxemia in acutely ill adults receiving supplemental oxygen.

JAMA Intern MedOct 1, 2026Read summary
Clinical ResearchPulmonologyOpen access

Efficacy and Safety of Traditional Chinese Medicine in Treating Chronic Obstructive Pulmonary Disease with Osteoporosis: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated the efficacy and safety of traditional Chinese medicine (TCM) as an adjunct to conventional treatment for chronic obstructive pulmonary disease (COPD) with osteoporosis…

Int J Chron Obstruct Pulmon DisOct 1, 2026Read summary
Clinical ResearchPulmonology

Davos@home: Integrating objective home monitoring into eHealth self-management support after alpine altitude climate treatment for severe asthma.

This 12-month pragmatic randomised trial assessed whether objective home monitoring adds benefit to eHealth self-management after Alpine Altitude Climate Treatment (AACT) in adults with severe asthma.

Respir MedOct 1, 2026Read summary

September 202612

Clinical ResearchPulmonology

Open versus closed suctioning on lung volume and oxygenation in ARDS patients with PEEP 5-10 cmH2O: A randomized controlled trial.

This randomized controlled trial compared open suctioning (OS) and closed suctioning (CS) in 60 ARDS patients on mechanical ventilation with PEEP 5-10 cmH2O.

PLoS OneSep 30, 2026Read summary
Clinical ResearchPulmonologyOpen access

A specialist-led interprofessional weaning program to prevent weaning failure in high-risk patients: the PRiVENT study.

The PRiVENT study evaluated a specialist-led interprofessional weaning program for high-risk mechanically ventilated patients in a multicenter, non-randomized trial.

Crit CareSep 30, 2026Read summary
Clinical ResearchPulmonology

Effects of pulmonary rehabilitation on lung hyperinflation in patients with COPD: A systematic review and meta-analysis.

This systematic review and meta-analysis assessed whether pulmonary rehabilitation (PR) affects static and dynamic lung hyperinflation in people with COPD.

Respir MedSep 29, 2026Read summary
Clinical ResearchOncology (Medical)

Prolonged survival after systemic immune reactivation by aglatimagene besadenovec plus valacyclovir in immune checkpoint inhibitor-refractory non-small cell lung cancer.

This phase 2a clinical trial evaluated the combination of aglatimagene besadenovec and valacyclovir in 76 patients with immune checkpoint inhibitor-refractory non-small cell lung cancer.

J Immunother CancerSep 28, 2026Read summary
Case ReportGastroenterology

Crohn's disease unmasks pulmonary sarcoidosis on biologic screening: dual granulomatous pathology responsive to infliximab.

A man in his 30s with a history of ileal Crohn's disease was diagnosed with pulmonary sarcoidosis during routine pre-biologic screening, despite being asymptomatic.

BMJ Case RepSep 28, 2026Read case
Case ReportPulmonology

Reversible bilateral cerebellar ataxia resulting from hypercapnic encephalopathy in an undiagnosed patient with obstructive sleep apnoea.

A man in his 40s with morbid obesity and type 2 diabetes presented with early-morning drowsiness and respiratory distress after nocturnal dyspnoea and diuretic use.

BMJ Case RepSep 28, 2026Read case
Case ReportInfectious DiseasesOpen access

Diagnostic Challenges in mNGS for Pulmonary Mucormycosis Presenting with Imaging Features Resembling Those of Lung Cancer.

A 67-year-old woman with diabetes presented with cough and sputum production. Imaging suggested lung cancer due to a right hilar mass, bronchial obstruction, and mediastinal lymphadenopathy.

Int Med Case Rep JSep 28, 2026Read case
Clinical ResearchOncology (Medical)

Systemic and intracranial activity of antibody-drug conjugates in patients with non-small cell lung cancer and brain metastases: A systematic review and meta-analysis.

This systematic review and meta-analysis assessed systemic and intracranial responses to antibody-drug conjugates (ADCs) in patients with non-small cell lung cancer and brain metastases.

Lung CancerSep 28, 2026Read summary
Case ReportInfectious Diseases

Pulmonary Actinomycosis Diagnosed via BALF mNGS in a 53-Year-Old Nonsmoking Man With Pneumoconiosis and Penicillin-Induced Thrombocytopenia: A Case Report.

A 53-year-old nonsmoking man with pneumoconiosis presented with a month-long history of cough and hemoptysis. Imaging revealed bilateral upper-lung masses and lymphadenopathy, leading to a right upper lobectomy under…

Am J Case RepSep 27, 2026Read case
Case ReportGeriatrics

Electrical Impedance Tomography-Guided Precision Nursing in an Older Patient With Septic Shock and ARDS: A Case Report.

A 79-year-old patient with septic shock, ARDS, and MODS underwent precision nursing management utilizing electrical impedance tomography (EIT).

Nurs Crit CareSep 26, 2026Read case
Clinical ResearchPulmonologyOpen access

Clinical Characteristics and Factors Associated with One-Year Smoking Cessation Among Smokers with COPD: A Subgroup Analysis of a Multicentre Randomised Trial.

This multicentre randomised trial evaluated factors associated with one-year smoking cessation among smokers with COPD. Of 172 patients analyzed, 32 (18.6%) achieved cessation, with 25.8% in the immediate referral group…

Int J Chron Obstruct Pulmon DisSep 26, 2026Read summary
Clinical ResearchPulmonology

Early cardiovascular vulnerability after acute exacerbation of COPD: a time-windowed systematic review and evidence map.

This systematic review and evidence map examined cardiovascular events during and after exacerbations of COPD, asthma, or bronchiectasis, with COPD as the primary evidence base.

Respir MedSep 26, 2026Read summary

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