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1333 articles
October 202624
Cerebrospinal fluid shunting for idiopathic normal pressure hydrocephalus: a comprehensive meta‑analysis with trial sequential analysis of randomized controlled trials.
This meta-analysis evaluated the efficacy of cerebrospinal fluid (CSF) shunting in adults aged 60 and older with idiopathic normal pressure hydrocephalus (iNPH).
Therapeutic value of continuous subcutaneous insulin infusion with electrolyte supplementation for pediatric diabetic ketoacidosis.
This randomized controlled trial evaluated the efficacy and safety of continuous subcutaneous insulin infusion (CSII) with electrolyte supplementation in 66 pediatric patients with diabetic ketoacidosis (DKA).
Effectiveness of a nurse-led telephonic brief intervention to reduce risky alcohol use among women in primary care in Brazil: a randomized controlled trial.
This randomized controlled trial evaluated a nurse-led telephonic brief intervention aimed at reducing risky alcohol use among 151 women in primary care in São Paulo, Brazil.
Treatment of hypertrophic scars using fractional CO2 laser alone in comparison with adding botulinium toxin either intalesional injection or assisted drug delivery.
This randomized controlled trial evaluated the effectiveness of fractional CO₂ laser treatment alone versus its combination with botulinum toxin A in 16 patients with post-burn hypertrophic scars.
Type II RAF Inhibitor Tovorafenib in Recurrent/Refractory Melanoma or Other Solid Tumors With BRAF Fusions or CRAF/RAF1 Fusions or Amplification: Phase II FIRELIGHT-1 Substudy.
This Phase II clinical trial evaluated the efficacy and safety of tovorafenib in 23 patients with recurrent/refractory solid tumors harboring BRAF or CRAF fusions/amplifications.
Safety profile of elafibranor versus placebo in primary biliary cholangitis: A systematic review, meta-analysis, and trial sequential analysis of randomized controlled trials.
This systematic review and meta-analysis evaluated the safety profile of elafibranor compared to placebo in patients with primary biliary cholangitis (PBC) who did not adequately respond to first-line therapy.
Serum 25-hydroxyvitamin D levels are associated with thyroid diseases: A systematic review and meta-analysis.
This systematic review and meta-analysis examined the relationship between serum 25-hydroxyvitamin D levels and thyroid diseases, including autoimmune thyroid diseases (AITDs).
Antibiotic Stewardship in Nonoperative Facial Trauma: Necessary or Not?
This systematic review evaluated the effectiveness of prophylactic antibiotics in preventing infections in adults with closed, nonoperative facial fractures.
Participant experiences of stopping ART as part of a clinical trial; findings from a qualitative study within the RIO trial in the United Kingdom.
This qualitative study explored the experiences of 20 cisgender men living with HIV who participated in the phase 2 RIO trial, which involved analytical treatment interruptions (ATIs).
Implementation of Communication Disability Documentation and Accommodations in Primary Care: A Pragmatic Type III Hybrid Implementation-Effectiveness Trial Protocol.
This article describes the protocol for the DECA study, a pragmatic Type III hybrid implementation-effectiveness trial of communication disability (CD) documentation and accommodation processes in primary care.
The effect of intermittent theta burst stimulation on central poststroke pain: A pilot randomized controlled trial.
This pilot randomized controlled trial investigated the effects of intermittent theta burst stimulation (iTBS) on central poststroke pain (CPSP) in 20 patients.
Renoprotective effects and safety of sodium-glucose cotransporter 2 inhibitors in diabetic chronic kidney disease: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the effects of sodium-glucose cotransporter 2 (SGLT2) inhibitors on patients with diabetic chronic kidney disease (CKD).
Genetic evidence for associations between gastroesophageal reflux disease and site-specific extraesophageal cancers: A Mendelian randomization study.
This Mendelian randomization study investigated the relationship between genetically predicted gastroesophageal reflux disease (GERD) and 22 extraesophageal cancers using data from over 600,000 individuals.
Patient Navigation and Postpartum Health Care Outcomes: A Randomized Clinical Trial.
This randomized clinical trial evaluated the impact of patient navigation on postpartum health care quality among low-income individuals.
Prevalence of metabolic syndrome among patients with Alzheimer disease: A systematic review and meta-analysis.
This systematic review and meta-analysis examined the prevalence of metabolic syndrome (MetS) in patients with Alzheimer disease (AD).
40 Hz transcutaneous auricular vagus nerve stimulation enhances verbal free recall in healthy adults by modulating frontal theta oscillations.
This randomized, single-blind, sham-controlled, three-arm trial examined whether 20 Hz or 40 Hz transcutaneous auricular vagus nerve stimulation (taVNS) affected verbal free recall and resting-state EEG theta activity…
Impact of acupuncture on lower limb motor function recovery after stroke: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the effects of acupuncture on lower limb motor function recovery after stroke, including six randomized controlled trials.
Regional practice differences significantly affect the benefit of post-HCT gilteritinib in FLT3-ITD AML.
The phase 3 MORPHO trial evaluated the efficacy of gilteritinib versus placebo in post-hematopoietic cell transplantation (HCT) for FLT3-ITD AML patients.
Incidence, severity, and associated risk factors for amyloid-related imaging abnormalities in anti-amyloid monoclonal antibody therapy for early Alzheimer's disease: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the incidence and risk factors for amyloid-related imaging abnormalities (ARIA) in 12,610 patients with early Alzheimer's disease receiving anti-amyloid monoclonal…
MRD negativity by PBMCs and ctDNA confirms deep and durable responses after epcoritamab monotherapy in R/R FL.
The EPCORE NHL-1 trial evaluated the efficacy of epcoritamab, a CD3 × CD20 bispecific antibody, in patients with relapsed/refractory follicular lymphoma (FL) after at least two prior therapies.
Genotype-Phenotype Relationships in Patients Carrying Biallelic FDXR Pathogenic Variants-New Cases and Systematic Review.
Biallelic pathogenic FDXR variations were identified in 2017 as being responsible for sensorial neuropathies. The first reported patients suffered from auditory and optic sensorineural impairments (ANOA, MIM #617717).
Facilitators of Peer Support Among Patients With Chronic Kidney Disease: A Systematic Review and Qualitative Meta-Synthesis.
This systematic review and qualitative meta-synthesis examined facilitators of peer support among patients with chronic kidney disease (CKD).
Treatment of Multifood Allergy With Omalizumab or Multiallergen Oral Immunotherapy: A Randomized Clinical Trial.
This randomized clinical trial compared the efficacy of omalizumab versus multiallergen oral immunotherapy (MOIT) in treating multifood allergies in participants aged 1 to 55 years.
Platelet-rich plasma versus corticosteroid injections for facet and sacroiliac joint pain: a systematic review and meta-analysis with trial sequential analysis.
This systematic review and meta-analysis evaluated the efficacy of platelet-rich plasma (PRP) versus corticosteroid injections for treating facet and sacroiliac joint pain in 392 patients.
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