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788 articles

February 20269

Clinical ResearchInfectious DiseasesOpen access

Comparative evaluation of molecular technologies for the identification of prevalent non-tuberculous mycobacteria in pulmonary infections: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed molecular methods for identifying non-tuberculous mycobacteria (NTM) and detecting antibiotic resistance in human studies published between 2005 and 2024.

Ann MedFeb 10, 2026Read summary
Case ReportInfectious Diseases

Invasive Pneumococcal Disease Presenting with Pyogenic Spondylitis in a Patient on Chronic Hemodialysis Who Previously Received a Pneumococcal Vaccine.

A woman receiving chronic hemodialysis presented with fever during a routine session, without focal signs. Blood cultures grew Streptococcus pneumoniae serotype 38, a non-vaccine serotype, despite prior pneumococcal…

Intern MedFeb 10, 2026Read case
Case ReportInfectious Diseases

Fatal Fungal Peritonitis Caused by Aspergillus udagawae: An Autopsy Case Report.

A 56-year-old man with chronic progressive pulmonary aspergillosis caused by multidrug-resistant Aspergillus udagawae developed acute abdominal pain.

Intern MedFeb 10, 2026Read case
Case ReportPulmonology

Levofloxacin-Induced Eosinophilic Pneumonia with Systemic Manifestations: A Case Report and Literature Review.

A 73-year-old man developed diffuse erythema, dyspnea, and renal impairment 22 days after starting levofloxacin. Evaluation showed marked eosinophilia and diffuse ground-glass opacities on chest CT.

Intern MedFeb 10, 2026Read case
Clinical ResearchInfectious Diseases

Adherence and efficacy of the 0 - 7 - 21-day versus the 0 - 1 - 6-month hepatitis B vaccination schedules among people who use drugs: a two-year randomized controlled trial.

This two-year randomized controlled trial compared hepatitis B vaccination schedules among 1261 HBV-susceptible people who use drugs in detoxification centers and methadone clinics in Xi'an, China.

Expert Rev VaccinesFeb 8, 2026Read summary
Clinical ResearchNephrologyOpen access

Prevalence of HIV-associated nephropathy in children: a systematic review with meta-analysis of studies published between 2004 and 2019.

This systematic review and meta-analysis estimated the prevalence of HIV-associated nephropathy among children living with HIV.

Pediatr NephrolFeb 6, 2026Read summary
Clinical ResearchInfectious DiseasesOpen access

Phase 1/2 randomized, observer-blind clinical trial of a first-generation, mRNA-based vaccine against seasonal influenza and COVID-19 in healthy adults.

This stratified, observer-blinded phase 1/2 randomized trial evaluated the safety and immune responses of a combined influenza and COVID-19 mRNA vaccine in healthy adults aged 18–75 years.

Hum Vaccin ImmunotherFeb 2, 2026Read summary
Clinical ResearchInfectious Diseases

Evidence for the efficacy and safety of pre-exposure prophylaxis (PrEP) in all populations: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed PrEP efficacy and safety across populations, including studies published in English, Portuguese, or Spanish from 2018 to 2023.

AIDS CareFeb 2, 2026Read summary
Case ReportInfectious Diseases

Campylobacter fetus Bacteremia Presenting with Bilateral Lower Leg Cellulitis in an Immunocompetent Adult.

An 87-year-old woman without immunodeficiency presented with fever and pain in both legs. Examination showed inflammatory changes in both lower legs, and blood cultures grew Campylobacter fetus.

Intern MedFeb 1, 2026Read case

January 202615

Clinical ResearchPulmonology

Detection of Pseudomonas aeruginosa in cystic fibrosis after initiation of CFTR modulators: a systematic review.

This systematic review examined how Pseudomonas aeruginosa is detected in people with cystic fibrosis treated with elexacaftor/tezacaftor/ivacaftor (ETI), including comparisons of culture and molecular methods.

Paediatr Respir RevJan 28, 2026Read summary
Clinical ResearchNeurologyOpen access

GPR3 in neuro-metabolic-immune-reproductive nexus - a potential therapeutic target for Multi-System diseases.

This systematic review examined GPR3, an orphan G-protein-coupled receptor, across neurological, metabolic, immune, and reproductive systems, drawing on a literature search of PubMed and Web of Science.

Ann MedJan 23, 2026Read summary
Clinical ResearchInfectious DiseasesOpen access

Modeling of antibody waning after heterologous boosting with Ad5-nCoV in individuals primed with two-dose CoronaVac previously.

This analysis integrated longitudinal serological data from three randomized trials in Jiangsu, China, to model antibody waning after aerosolized or intramuscular Ad5-nCoV boosting in people primed with two doses of…

Hum Vaccin ImmunotherJan 22, 2026Read summary
Clinical ResearchPediatricsOpen access

Clinical effectiveness and impact of 13-valent pneumococcal conjugate vaccines in preventing invasive pneumococcal disease among children with risk conditions: A systematic literature review.

This systematic literature review assessed PCV13 efficacy, effectiveness, and population impact for invasive pneumococcal disease (IPD) and all-cause pneumonia in children with immunocompromising or chronic medical risk…

Hum Vaccin ImmunotherJan 20, 2026Read summary
Case ReportInfectious DiseasesOpen access

Congenital babesiosis in China: first molecularly confirmed case of vertical transmission of Babesia microti .

A 74-day-old boy presented with fever, pallor, and severe haemolytic anaemia (haemoglobin 45 g/L). Peripheral blood smear showed ring forms and 16% parasitemia.

Emerg Microbes InfectJan 20, 2026Read case
Clinical ResearchPsychiatryOpen access

The efficacy and mechanism of an integrated mindfulness-based programme on posttraumatic stress disorder among people with HIV: a randomized controlled trial with 3-month follow up.

This randomized controlled trial evaluated an Integrated Mindfulness-Based Programme (IMBP), combining the Community Resiliency Model and mindfulness-based stress reduction, in 82 people with HIV and PTSD.

Eur J PsychotraumatolJan 19, 2026Read summary
Clinical ResearchInfectious DiseasesOpen access

Global molecular epidemiology of Mycoplasma pneumoniae and its association with macrolide resistance and disease severity: a systematic review and meta-analysis.

This systematic review and meta-analysis examined the global distribution of Mycoplasma pneumoniae genotypes and their associations with macrolide resistance and disease severity among infected patients.

Emerg Microbes InfectJan 16, 2026Read summary
Case ReportInfectious Diseases

Pneumatosis Cystoides Intestinalis Secondary to Antibiotic Therapy for Pulmonary Mycobacterium avium Complex Infection: A Case Report and Review of the Literature.

An 83-year-old woman receiving antibiotic therapy for pulmonary Mycobacterium avium complex infection developed pneumatosis cystoides intestinalis (PCI), characterized by gas within the gastrointestinal wall.

Intern MedJan 15, 2026Read case
Case ReportObstetrics & Gynecology

Cervico-vaginal Amoebiasis Masquerading as Malignancy-A Case Series Highlighting Rare Clinical Presentation of a Common Parasitic Infection.

Three women presented with lower genital tract lesions that appeared clinically and radiologically suspicious for malignancy.

Int J Gynecol PatholJan 14, 2026Read case
Clinical ResearchInfectious DiseasesOpen access

Sustained salivary IgG but short-lived IgA responses following primary and booster MenACWY-TT vaccination in older adults.

This phase IV, open-label clinical trial assessed salivary antibody responses after primary MenACWY-TT vaccination in 216 adults aged 65–85 years; 100 participants received a booster one year later.

Hum Vaccin ImmunotherJan 8, 2026Read summary
Case ReportDermatology

Case Report of an Uncommon Dermatologic Manifestation of Disseminated Stenotrophomonas Maltophilia Infection in a Patient With Aplastic Anemia.

An immunocompromised patient with aplastic anemia receiving antithymocyte globulin, cyclosporine, and methylprednisolone developed ecthyma gangrenosum associated with disseminated Stenotrophomonas maltophilia infection.

J Pharm PractJan 8, 2026Read case
Clinical ResearchGastroenterologyOpen access

Epidemiological characteristics of rotavirus gastroenteritis in China: A systematic review of studies published from 2014 to 2023.

This systematic review analysed 320 studies published from 2014 to 2023 on rotavirus gastroenteritis (RVGE) incidence, population distribution and genotypes in China.

Hum Vaccin ImmunotherJan 7, 2026Read summary
Clinical ResearchInfectious DiseasesOpen access

Immunogenicity and safety of 20-valent pneumococcal conjugate vaccine in pneumococcal vaccine-naive adults ≥18 years of age in India: A phase 3 single-arm trial.

This phase 3, multicenter, single-arm trial assessed immunogenicity and safety of one dose of 20-valent pneumococcal conjugate vaccine (PCV20) in pneumococcal vaccine-naive adults aged ≥18 years in India.

Hum Vaccin ImmunotherJan 7, 2026Read summary
Clinical ResearchInfectious DiseasesOpen access

Andrographolide Sulfonate Injection for Adjunctive Treatment of Non-severe Community-Acquired Pneumonia in Adults: A Multicenter, Double-Blind, Randomized Controlled Trial.

This multicenter, double-blind, placebo-controlled randomized trial evaluated adjunctive andrographolide sulfonate (AS) injection in adults hospitalized with non-severe community-acquired pneumonia receiving standard…

Chin J Integr MedJan 5, 2026Read summary
Case ReportNeurologyOpen access

Unmasking a B-Cell Linkage Phenotype in Severe Acute Meningoencephalitis: A Case Report of IVIG and HydroBox-assisted Immunomodulatory Therapy.

A previously healthy 30-year-old man developed fulminant acute meningoencephalitis with coma, respiratory failure, and severe systemic inflammation.

In VivoJan 1, 2026Read case

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