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962 articles

April 202624

Clinical ResearchCardiology

Short-term outcomes of ticagrelor monotherapy after primary percutaneous coronary intervention for ST-elevation myocardial infarction: A randomized pilot study.

This randomized pilot study evaluated the safety of ticagrelor monotherapy compared to ticagrelor plus aspirin in 200 STEMI patients after primary PCI.

Am Heart JApr 28, 2026Read summary
Case ReportCardiologyOpen access

The Rare Fifth Chamber of the Heart: Double-Chambered Left Ventricle.

A patient presented with chest pain and was found to have a double-chambered left ventricle, a rare congenital cardiac anomaly characterized by the division of the left ventricle into two chambers.

J Clin UltrasoundApr 28, 2026Read case
Case ReportCardiology

Supracardiac Total Anomalous Pulmonary Venous Connection with Left Main Bronchial Compression in an Infant.

A 4-month-old male infant presented with supracardiac total anomalous pulmonary venous connection (TAPVC) and left main bronchial stenosis, alongside a central atrial septal defect and severe pulmonary hypertension.

World J Pediatr Congenit Heart SurgApr 28, 2026Read case
Clinical ResearchCardiology

Surgical versus percutaneous revascularization in multivessel non-ST-elevation acute coronary syndrome: a meta-analysis of 77 989 patients.

This meta-analysis compared coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI) in 77,989 patients with multivessel non-ST-elevation acute coronary syndrome.

Coron Artery DisApr 27, 2026Read summary
Clinical ResearchCardiologyOpen access

ADA-HF: acetazolamide as a chloride sparing diuretic in patients admitted to hospital with heart failure.

The ADA-HF study evaluated the effects of oral acetazolamide (ACZ) on diuresis and chloride loss in hospitalized heart failure patients.

Clin Res CardiolApr 27, 2026Read summary
Clinical ResearchCardiologyOpen access

HI-PLUS: design of a cluster-randomized trial evaluating structured case management with telemonitoring to improve quality of life in heart failure.

The HI-PLUS trial is a cluster-randomized controlled trial designed to evaluate a structured case management intervention with telemonitoring aimed at improving quality of life in heart failure patients.

Clin Res CardiolApr 27, 2026Read summary
Case ReportCardiology

Resolution of Refractory Multifocal Atrial Tachycardia in Costello Syndrome Using Trametinib: A Case Supporting MEK Inhibitors as Targeted, Specific Antiarrhythmic.

An infant with Costello syndrome and a pathogenic HRAS variant presented with drug-refractory multifocal atrial tachycardia (MAT).

Am J Med Genet AApr 27, 2026Read case
Clinical ResearchCardiology

Exploring the role of successful exercise-induced body weight loss on cardiometabolic health in individuals with metabolic syndrome.

This randomized controlled trial investigated the impact of high-intensity interval training (HIIT) on cardiometabolic health in 228 adults with metabolic syndrome.

Nutr Metab Cardiovasc DisApr 25, 2026Read summary
Case ReportCardiology

Hybrid Technique for a Rare Complication of Cardiac Devices Implantation.

A 90-year-old man presented with early cardiac lead perforation following device implantation. The diagnosis was suspected due to capture failure on the electrocardiogram and confirmed by chest computed tomography.

Pacing Clin ElectrophysiolApr 25, 2026Read case
Clinical ResearchCardiology

Cerebral embolic protection devices for transcatheter aortic valve replacement: A meta-analysis and trial sequential analysis.

This meta-analysis evaluated the efficacy of current-generation cerebral embolic protection devices (CEPDs) during transcatheter aortic valve replacement (TAVR) across 8 randomized controlled trials involving 11,596…

Am Heart JApr 24, 2026Read summary
Clinical ResearchCardiologyOpen access

A systematic review of physical activity guidelines for adults with cardio-respiratory diseases: Stepping towards evidence-based recommendations.

This systematic review evaluated physical activity guidelines for adults with cardio-respiratory diseases, including chronic obstructive pulmonary disease, asthma, and heart failure.

Clin RehabilApr 24, 2026Read summary
Clinical ResearchCardiology

Cognitive function and anticoagulation discontinuation in patients without long-term recurrence after catheter ablation for atrial fibrillation: A substudy of the ALONE-AF trial.

This substudy of the ALONE-AF trial evaluated the cognitive effects of oral anticoagulant (OAC) discontinuation in patients aged 19-80 years without atrial fibrillation recurrence after catheter ablation.

Heart RhythmApr 24, 2026Read summary
Clinical ResearchCardiology

Rationale and design of the vericiguat in vasospastic angina (ViVA) trial: A double-blind placebo-controlled randomized cross-over study.

The Vericiguat in Vasospastic Angina (ViVA) trial is a double-blind, placebo-controlled randomized cross-over study investigating the effects of vericiguat on patients with angina and no obstructive coronary arteries…

Am Heart JApr 23, 2026Read summary
Clinical ResearchCardiology

Beta-blockers after invasively managed STEMI vs NSTEMI without reduced ejection fraction: a prespecified analysis from the REBOOT trial.

This prespecified analysis from the REBOOT trial evaluated the long-term effects of beta-blockers in invasively managed myocardial infarction (MI) patients with preserved left ventricular ejection fraction (LVEF).

Rev Esp Cardiol (Engl Ed)Apr 23, 2026Read summary
Clinical ResearchCardiology

Clinical and echocardiographic predictors of reintervention after percutaneous or surgical treatment of rheumatic mitral stenosis: A systematic review.

This systematic review examined clinical and echocardiographic predictors of outcomes following percutaneous or surgical treatment for rheumatic mitral stenosis.

Curr Probl CardiolApr 22, 2026Read summary
Clinical ResearchCardiologyOpen access

Impact of Aspirin on Primary Prevention of Cardiovascular Events in Patients with Elevated Lipoprotein(a): A Systematic Review and Meta-analysis.

This systematic review and meta-analysis evaluated the effect of aspirin on cardiovascular events in patients with elevated lipoprotein(a) (Lp(a)).

Am J Cardiovasc DrugsApr 22, 2026Read summary
Case ReportCardiology

Postcardiotomy veno-arterial membrane oxygenation as a bridge to heart replacement therapies.

Data on the outcome of veno-arterial extracorporeal membrane oxygenation (V-A-ECMO) support as a bridge to replacement therapies are scarce.

Heart LungApr 21, 2026Read case
Clinical ResearchCardiology

The effect of low-carbohydrate diets on serum concentration of soluble adhesion molecules: a systematic review and meta-analysis of randomized controlled trials.

This systematic review and meta-analysis evaluated the impact of low-carbohydrate diets (LCDs) on serum levels of adhesion molecules in adults.

Int J Environ Health ResApr 21, 2026Read summary
Clinical ResearchCardiology

Conduction System Pacing vs Right Ventricular Pacing in Preserved or Mildly Reduced Ejection Fraction: A Meta-Analysis of Randomised Trials.

This meta-analysis of 15 randomized controlled trials involving 1466 patients with preserved or mildly reduced left ventricular ejection fraction compared conduction system pacing (CSP) to right ventricular pacing…

Can J CardiolApr 21, 2026Read summary
Clinical ResearchCardiology

Influence of Baseline Smoking Status on Intensive Blood Pressure Control: Results From the STEP Randomized Trial.

This secondary analysis of the STEP randomized trial evaluated the impact of baseline smoking status on cardiovascular outcomes in 8489 elderly hypertensive patients.

Can J CardiolApr 21, 2026Read summary
Case ReportCardiology

Customized Sheath Modification for Bachmann Bundle Area Pacing With a Stylet-Driven Lead.

Two patients underwent Bachmann bundle area pacing (BBp) using a modified standard ventricular delivery catheter. The catheter was shortened and reshaped through controlled heat molding, allowing stable placement of a…

Pacing Clin ElectrophysiolApr 21, 2026Read case
Clinical ResearchCardiology

Clinical Outcomes of Different Heparin Anticoagulation Monitoring Targets in Extracorporeal Membrane Oxygenation: A Systematic Review and Meta-analysis.

This systematic review and meta-analysis evaluated the clinical outcomes of conservative versus standard heparin anticoagulation protocols during extracorporeal membrane oxygenation (ECMO) in 601 patients.

J Cardiothorac Vasc AnesthApr 20, 2026Read summary
Clinical ResearchCardiology

The Impact of Periodontal Health Interventions on the Risk of Ischemic Stroke: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis examined the impact of periodontal health interventions on the risk of first-ever ischemic stroke, analyzing data from seven studies with 1,886,947 participants.

Int J Dent HygApr 20, 2026Read summary
Clinical ResearchCardiology

Treatment of OSA using mandibular advancement versus CPAP in improving cardiovascular health.

This randomized controlled trial compared the effectiveness of mandibular advancement devices (MAD) and continuous positive airway pressure (CPAP) in reducing 24-hour ambulatory blood pressure in 220 participants with…

Am J MedApr 19, 2026Read summary

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