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1821 articles
August 202624
Neoadjuvant Intralesional Daromun (L19IL2/L19TNF) in Resectable Locally Advanced Melanoma: An Update on the Efficacy and Safety Results of the PIVOTAL Phase III Trial.
The PIVOTAL Phase III trial evaluated the efficacy and safety of neoadjuvant intralesional daromun (L19IL2/L19TNF) in 256 patients with fully resectable stage III melanoma.
suPAR as a circulating inflammatory biomarker: time for translation into clinical practice - A systematic review.
This systematic review examines soluble urokinase-type plasminogen activator receptor (suPAR) as a circulating biomarker, its isoforms, and methods used to measure it.
68 Ga-FAPI-04 PET/CT Detection of Peritoneal Metastases From a Rare Uterine Tumor Resembling Ovarian Sex-cord Tumor.
Uterine tumor resembling ovarian sex-cord tumor (UTROSCT) is an extremely rare uterine stromal neoplasm of uncertain origin that accounts for less than 0.5% of uterine malignancies.
Disseminated Salmonella infection associated with secondary seeding of an indwelling central venous catheter during chemotherapy-induced neutropenia.
A patient undergoing outpatient chemotherapy for a gynecological malignancy developed a disseminated Salmonella infection, likely acquired from fresh confectionery.
Parkinsonism as a Potential Neurologic Immune-Mediated Adverse Event of Immune Checkpoint Inhibitors.
Immune checkpoint inhibitor (ICI)-related parkinsonism is an exceedingly rare neurologic immune-related adverse event (irAE).
A Case of FDG-Avid but FAPI-Negative Peritoneal Metastatic Gastrointestinal Stromal Tumor.
An 80-year-old man with a biopsy-confirmed metastatic gastrointestinal stromal tumor underwent both 18F-FDG PET/CT and 68Ga-FAPI PET/CT imaging.
Effects of different resistance exercise programs on upper limb functional recovery in postoperative breast cancer patients.
This randomized controlled trial examined the impact of grip strength exercises combined with upper limb resistance exercises on functional recovery in 111 postoperative breast cancer patients.
Inflammation hinders anabolic potential of nutritional support in cancer: findings from the Protein Recommendation to Increase Muscle (PRIMe) trial.
The PRIMe trial analyzed the impact of baseline inflammation on the effectiveness of high-protein nutritional support in patients with stage II-IV colorectal cancer.
Metabolic Tumor Volume Is More Accurate Than SUV Metrics in PSMA-PET/CT Analysis Across Different PET/CT Scanners.
A 66-year-old man with metastatic prostate cancer had PSMA-avid local recurrence on follow-up PSMA-PET/CT and MRI. Across three PET studies, SUVmax, SUVmean, and total lesion glycolysis (TLG) did not track consistently…
Therapeutic targeting of folate receptor alpha (FRα) by antibody-polymer-drug conjugate in testicular germ cell tumors.
Antibody-drug conjugates (ADCs) are an effective treatment for recurrent/refractory testicular germ cell tumors (rrTGCTs). In this exploratory study, we report disease stabilization achieved with the ADC Mirvetuximab…
Ultra-hypofractionated versus conventional chemoradiation for newly diagnosed glioblastoma: Survival and toxicity results of a multicenter randomized trial.
This phase III randomized trial evaluated the non-inferiority of ultra-hypofractionated chemoradiation (6x6Gy) versus standard chemoradiation (30x2Gy) in adults with newly diagnosed glioblastoma.
Clinical Reasoning: A 79-Year-Old Man With Subacute Onset Involuntary Facial Movements and Discoordination.
A 79-year-old man with metastatic Merkel cell carcinoma undergoing cancer-directed treatment was admitted to the hospital with 1 week of bilateral upper and lower extremity tremor and nearly continuous involuntary…
De-escalation of radiotherapy in HPV-negative non-nasopharyngeal head and neck squamous cell carcinoma: a systematic review.
This systematic review evaluated de-escalation strategies in radiotherapy for HPV-negative non-nasopharyngeal head and neck squamous cell carcinoma (HNSCC).
Prediction of benefit from docetaxel chemotherapy for HR-positive breast cancer in the PACS-01 trial.
This randomized controlled trial evaluated the predictive value of the SET ER/PR index for docetaxel benefit in node-positive, hormone receptor-positive breast cancer patients from the PACS-01 trial.
A rare case of cytomegalovirus mucositis resembling an immune-related adverse event during treatment with nivolumab and ipilimumab.
A 79-year-old man with malignant melanoma of the sphenoid sinus was treated with nivolumab and ipilimumab. He developed immune-related colitis, treated with corticosteroids and infliximab.
Dissecting a Diagnostic Enigma, Multiple Bilateral Facial Nodules in a Middle Aged Woman.
A 40-year-old woman presented with multiple bilateral facial nodules in a zosteriform pattern, which had increased over 15 years.
Pain response after palliative-intent radiotherapy for pancreatic cancer: a systematic review.
This systematic review evaluated the effectiveness of palliative-intent radiotherapy (RT) for pain relief in pancreatic cancer patients.
Multidisciplinary treatment with conversion surgery after radiological complete response of liver metastasis to gemcitabine, cisplatin, and durvalumab in metastatic distal cholangiocarcinoma.
A 73-year-old woman with prior total gastrectomy was diagnosed with distal cholangiocarcinoma and a solitary liver metastasis.
Multifocal primary hepatic epithelioid hemangioendothelioma: a case in which tumor biopsy was critical to prevent misdiagnosis.
An 82-year-old woman undergoing postoperative surveillance for bladder cancer was found to have multiple hepatic masses on contrast-enhanced CT.
Uncovering an uncommon diagnosis: Encapsulated papillary carcinoma of the male breast in a Jordanian patient-A case report.
A 58-year-old male presented with a stable, non-painful left breast mass, initially misdiagnosed as a lipoma. Imaging revealed a suspicious BIRADS 4 mass, and intraoperative frozen section suggested malignancy.
Detection of an inflammatory myofibroblastic tumor in the testis by FDG-PET/CT; a rare presentation of a rare neoplasm.
FDG-PET/CT in a 73-year-old man revealed incidental FDG accumulation in the left testicle which was eventually diagnosed as an inflammatory myofibroblastic tumor (IMT): a rare localization of a rare tumor.
Health-Related quality of life (HRQoL) and health state utility values (HSUV) in patients with head and neck Cancer: A systematic review and Meta-Analysis.
This systematic review and meta-analysis evaluated health-related quality of life (HRQoL) and health state utility values (HSUV) in 7,403 patients with head and neck cancer (HNC).
Secondary Ameloblastic Carcinoma With Craniofacial and Skull Base Invasion: En Bloc Resection and Dural Reconstruction.
A 27-year-old male with a 13-year history of recurrent mandibular ameloblastoma presented with extensive craniofacial progression and regional lymph node metastases.
Longitudinal Change in Cardiac Function After Doxorubicin and Dexrazoxane: A Report From Children's Oncology Group ALTE11C2.
This randomized controlled trial analyzed echocardiographic data from 895 childhood cancer survivors treated with doxorubicin, assessing the long-term effects of dexrazoxane on cardiac function.
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