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1018 articles

April 202624

Case ReportPediatricsOpen access

Ultrasound Diagnosis of Giant Testicular Adrenal Residual Tumors: A Case Report and Literature Review.

A 9-year-old male with congenital adrenal hyperplasia presented with giant testicular adrenal residual tumors (TARTs) associated with 11β-hydroxylase deficiency.

J Clin UltrasoundApr 21, 2026Read case
Clinical ResearchPediatricsOpen access

Elevated serum creatinine over the first week of life and mortality risk in extremely preterm neonates: a secondary analysis of the Preterm Erythropoietin Neuroprotection Trial (PENUT).

This secondary analysis of the Preterm Erythropoietin Neuroprotection Trial evaluated the association between elevated serum creatinine (SCr) levels and mortality risk in extremely preterm neonates (<28 weeks…

Pediatr NephrolApr 21, 2026Read summary
Clinical ResearchPediatricsOpen access

Distal humerus physeal fractures in children under 3 years: a systematic review and quantitative descriptive analysis.

To conduct a systematic review on the imaging diagnosis and modality-specific characterization of distal humerus physeal fractures among children under 3 years of age.

Skeletal RadiolApr 21, 2026Read summary
Clinical ResearchPediatrics

Comparing Buzzy Ⓡ and Pikluc Ⓡ for Pain Relief in Pediatric Intramuscular Injections: A Randomized Equivalence Trial.

This randomized equivalence trial evaluated the effectiveness of Buzzy Ⓡ and Pikluc Ⓡ for pain relief during intramuscular injections in children aged 1-11 years.

Pain Manag NursApr 21, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Delayed versus Early Umbilical Cord Clamping in Preterm Multiple Gestation: A Randomized Controlled Trial.

This randomized controlled trial evaluated the effects of delayed cord clamping (DCC) versus early cord clamping (ECC) in 155 preterm infants from multiple gestations.

Am J PerinatolApr 21, 2026Read summary
Case ReportOncology (Medical)

False Positive Findings on 18F-MFBG PET/CT Attributable to Benign Neural Differentiation in a Pediatric Patient With Neuroblastoma.

A 5-year-old girl with high-risk neuroblastoma underwent an 18F-MFBG PET/CT scan to evaluate indeterminate lesions seen on prior imaging.

Clin Nucl MedApr 20, 2026Read case
Clinical ResearchAllergy & Immunology

Circulating Piwi-Interacting RNAs Associate With Childhood Asthma ICS Response With Vitamin D Effect Modification.

This randomized controlled trial investigated the association of circulating piwi-interacting RNAs (piRNAs) with inhaled corticosteroid (ICS) response in 492 children with asthma.

Clin Exp AllergyApr 20, 2026Read summary
Clinical ResearchPediatrics

Hand, foot, and mouth disease: A systematic review of global evidence, climatic drivers, and research gaps (2000-2023).

This systematic review analyzed 125 studies on hand, foot, and mouth disease (HFMD) from 2000 to 2023, primarily focusing on children under five.

Infect Dis HealthApr 19, 2026Read summary
Case ReportPediatrics

Foreign Body Aspiration Presenting as Recurrent Bronchiolitis: Case Report.

A toddler presented with recurrent wheezing and cough that did not improve with standard treatment. Evaluation at a pediatric urgent care center raised concerns for airway obstruction, leading to transfer to a pediatric…

J Pediatr Health CareApr 18, 2026Read case
Case ReportMedical Genetics

A Novel YY1AP1 Variant in Grange Syndrome: Clinical and Molecular Findings in Eight Individuals With a Dual Molecular Diagnosis Involving CLMP in One Patient.

This report describes eight individuals from a consanguineous family diagnosed with Grange syndrome, characterized by multiple fractures, bone fragility, and other systemic manifestations.

Am J Med Genet AApr 17, 2026Read case
Case ReportPediatrics

Acquired Syphilis in a Family Cluster Without Evidence of Sexual Transmission.

A family cluster presented with multiple cases of acquired syphilis in pediatric patients, with no evidence of sexual transmission. The index case and a sibling were evaluated, revealing no signs of sexual abuse.

Actas DermosifiliogrApr 16, 2026Read case
Case ReportOtolaryngology (ENT)Open access

Endoscopic-Assisted Transcervical Excision of Second Branchial Cleft Anomalies in Young Children.

This report details the use of an endoscopic-assisted transcervical technique for excising second branchial cleft anomalies in three young children aged 2 to 8 years.

LaryngoscopeApr 16, 2026Read case
Clinical ResearchEmergency Medicine

The Effect of Virtual Reality on Pain Management in Children in the Emergency Department: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated the impact of virtual reality on pain and anxiety management in children aged 2-17 undergoing medical procedures in emergency departments.

J Emerg NursApr 16, 2026Read summary
Clinical ResearchOphthalmologyOpen access

Management and presentation of pediatric thyroid eye disease: A systematic review and meta-analysis.

BackgroundPediatric Thyroid Eye Disease (TED) is a rare autoimmune condition primarily associated with Graves' disease. Although usually milder than adult TED, it can still cause functional and psychological morbidity.

Eur J OphthalmolApr 16, 2026Read summary
Case ReportPediatrics

Neonatal priapism revealing polycythemia: A rare association-Case report.

A male neonate born at 37 + 3 weeks developed painless priapism on the first day of life, lasting approximately 48 h. There was no penile discoloration or distress.

J Neonatal Perinatal MedApr 16, 2026Read case
Clinical ResearchPediatricsOpen access

Impact of climate change on pediatric health outcomes.

This systematic review assessed evidence linking climate exposures with health outcomes in children. It included 23 peer-reviewed studies published in 2000–2025, spanning different regions and study designs, and…

Glob Health ActionApr 15, 2026Read summary
Clinical ResearchAnesthesiology

Effect of General Anesthesia Combined with Single-Shot, Single-Level Thoracic Paravertebral Block on Postoperative Analgesia in Children Undergoing Thoracoscopic Mediastinal Tumor Resection: A Randomized Controlled Trial.

This single-centre prospective randomised controlled trial evaluated unilateral, ultrasound-guided, single-level thoracic paravertebral block (TPVB) in children aged 4–12 years undergoing thoracoscopic mediastinal tumor…

J Cardiothorac Vasc AnesthApr 15, 2026Read summary
Clinical ResearchPediatrics

Nurse-led family interactive intervention in children with bronchopneumonia: a randomized controlled trial.

This prospective randomized controlled trial evaluated a nurse-led family interactive psychological intervention in 91 hospitalized children with bronchial asthma and their primary caregivers.

J AsthmaApr 15, 2026Read summary
Case ReportPediatrics

Giant Pseudoangiomatous Stromal Hyperplasia Presenting as Bilateral Macromastia in an 11-Year-Old Female Patient: Emphasis on Pediatric Presentation and Literature Review.

An 11-year-old premenarchal girl presented with rapidly progressive bilateral breast enlargement, diagnosed as giant pseudoangiomatous stromal hyperplasia (PASH).

Int J Surg PatholApr 15, 2026Read case
Clinical ResearchPediatrics

Prophylactic sucrose via the tahneek technique and its effect on neonatal hypoglycemia randomized control trial.

This single-centre, open-label randomised controlled trial assessed whether tahneek with date paste reduced hypoglycemia in high-risk newborns.

J Neonatal Perinatal MedApr 15, 2026Read summary
Case ReportPediatricsOpen access

Pneumococcal HUS in infancy masking DGKE-related thrombotic microangiopathy with secondary hemophagocytic lymphohistiocytosis.

A 7-month-old boy presented with pneumonia, anemia, thrombocytopenia, and acute kidney injury. Pneumonia on imaging, elevated CRP, and a positive nasopharyngeal pneumococcal PCR initially supported…

Pediatr NephrolApr 14, 2026Read case
Clinical ResearchPsychiatryOpen access

What are the correlates of non-suicidal self-injury in children and adolescents? An umbrella systematic review of global evidence.

This umbrella systematic review synthesised meta-analyses of observational studies examining correlates of non-suicidal self-injury (NSSI) in children and adolescents.

Mol PsychiatryApr 14, 2026Read summary
Case ReportCardiology

Unexpected Pediatric Cardiac Arrest in a Toddler: A Case of Catecholaminergic Polymorphic Ventricular Tachycardia Presenting as Ventricular Fibrillation.

A previously healthy 2-year-old boy became pulseless after collapsing during a tantrum. EMS found ventricular fibrillation and delivered a 70-J biphasic shock (~4 J/kg), restoring circulation.

Pediatr Emerg CareApr 13, 2026Read case
Clinical ResearchPediatrics

A Randomized, Double-Blinded, Placebo-Controlled Trial of Homeopathy in Acute Viral Tonsillitis in Children.

This single-centre, double-blind, randomized, placebo-controlled trial evaluated individualized homeopathic medicines (IHMs), added to supportive care, in 78 children with acute viral tonsillitis.

J Integr Complement MedApr 10, 2026Read summary

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