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1088 articles

May 202620

Clinical ResearchPsychiatry

Effects of a novel individualized digital cognitive training on ADHD characteristics, quality of life, and cognitive functioning in adults with ADHD: A randomized controlled trial.

This randomized controlled trial evaluated the effects of the digital cognitive training application 'NeuroNation MED' on adults with ADHD.

J Psychiatr ResMay 12, 2026Read summary
Clinical ResearchPsychiatry

The impacts of trauma and stress on orexin expression and signalling: A systematic review.

This systematic review evaluated the effects of trauma and stress on orexin expression and signaling across preclinical and clinical studies.

Psychiatry ResMay 11, 2026Read summary
Clinical ResearchPsychiatryOpen access

Comparison of the clinical efficacy, safety and EEG functional connectivity changes between 18-Hz rTMS and iTBS of accelerated dTMS treatment for major depressive disorder: a randomized controlled trial.

This randomized controlled trial compared the efficacy and safety of 18-Hz rTMS and iTBS of accelerated dTMS in 73 patients with major depressive disorder (MDD).

Mol PsychiatryMay 11, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Motivating paternal empathy and egalitarian attitudes to prevent maternal postpartum depressive symptoms: A randomized controlled trial.

This single-blind, parallel-group randomized controlled trial at a regional hospital in Japan tested a brief online intervention for fathers, delivered one month after birth, to promote empathy and egalitarian…

Int J Gynaecol ObstetMay 11, 2026Read summary
Clinical ResearchPsychiatry

Safety and efficacy of ashwagen (a standardized withania somnifera extract) in stress and anxiety with hypertension and associated cardiometabolic risk factors: a randomized, placebo-controlled trial.

This randomized, double-blind, placebo-controlled Phase III trial evaluated the safety and efficacy of Ashwagen®, a standardized Withania somnifera extract, in 60 patients with stress, anxiety, and pre-existing…

StressMay 9, 2026Read summary
Clinical ResearchPsychiatryOpen access

Integrating cell-type-specific gene expression and genome-wide associations identifies risk genes for schizophrenia.

This meta-analysis investigated the causal relationships between cell-type-specific gene expression and schizophrenia (SCZ) using expression quantitative trait loci (eQTL) data.

Mol PsychiatryMay 9, 2026Read summary
Clinical ResearchPsychiatryOpen access

Disclosing mental health in medical education: A global qualitative meta-synthesis.

This international qualitative meta-synthesis examined how medical students experience and navigate disclosure of mental health disorders.

Med EducMay 8, 2026Read summary
Clinical ResearchGeriatricsOpen access

Effectiveness of Nurse-Led Interventions in Older Adults With Mild Cognitive Impairment or Dementia: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated the effectiveness of nurse-led interventions in older adults with mild cognitive impairment or dementia.

J Clin NursMay 7, 2026Read summary
Clinical ResearchPsychiatryOpen access

Cognitive behavioral telehealth treatment for adolescents with loss-of-control eating: A randomized controlled feasibility study.

This randomized controlled trial evaluated the feasibility and acceptability of a telehealth cognitive behavioral therapy (CBT) intervention for adolescents aged 12-17 with loss-of-control (LOC) eating.

Psychotherapy (Chic)May 7, 2026Read summary
Clinical ResearchPsychiatry

Experiential Interventions for Externalizing Behavior: A Multilevel Meta-Analysis of Adolescents and Adults.

This meta-analysis evaluated the effectiveness of experiential interventions in reducing externalizing behaviors among adolescents and adults, analyzing 39 studies with 2,323 participants.

Int J Offender Ther Comp CriminolMay 6, 2026Read summary
Clinical ResearchPsychiatry

Effects of ketamine on sleep and circadian rhythmicity in major depressive disorder and bipolar disorder: A systematic review.

This systematic review evaluated the effects of ketamine on sleep and circadian rhythms in patients with major depressive disorder (MDD) and bipolar disorder (BD).

J Affect DisordMay 6, 2026Read summary
Clinical ResearchPsychiatry

Longitudinal mapping of a randomized controlled trial of EEG neurofeedback in PTSD: Early symptom stabilization and implications for adjunctive therapeutic potential.

This randomized controlled trial investigated the effects of alpha-rhythm EEG neurofeedback on PTSD symptoms in 38 individuals over 20 weeks.

Psychiatry Res NeuroimagingMay 6, 2026Read summary
Clinical ResearchPsychiatry

Clinical and Cognitive Outcomes Comparing Right Unilateral Ultrabrief Electroconvulsive Therapy Versus Magnetic Seizure Therapy for Bipolar Depression: The CORRECT-BD Trial.

The CORRECT-BD trial compared the clinical efficacy and cognitive effects of magnetic seizure therapy (MST) and right unilateral ultrabrief-pulse electroconvulsive therapy (RUL-UB ECT) in patients with bipolar…

Am J PsychiatryMay 6, 2026Read summary
Clinical ResearchPsychiatry

Structural and functional brain correlates of treatment-resistant depression: A systematic review of magnetic resonance imaging studies.

This systematic review examined structural and functional brain changes in treatment-resistant depression (TRD) compared to non-treatment-resistant major depressive disorder (MDD).

J Affect DisordMay 5, 2026Read summary
Clinical ResearchPsychiatry

Written exposure therapy for post-traumatic stress disorder in residential treatment for substance use disorders: A randomized feasibility trial.

This randomized controlled trial evaluated the feasibility of Written Exposure Therapy (WET) combined with treatment as usual (TAU) for PTSD in 42 participants undergoing residential treatment for substance use…

Addict BehavMay 5, 2026Read summary
Clinical ResearchPsychiatry

Can positive mental imagery help high worriers stop worrying? An experimental test.

This randomized controlled trial investigated the effectiveness of positive mental imagery in helping high worriers (N = 201) stop worrying.

J Behav Ther Exp PsychiatryMay 2, 2026Read summary
Clinical ResearchPsychiatry

Comparative effects of non-pharmacological interventions on anxiety, depression and quality of life in individuals with substance use disorders: A systematic review and network meta-analysis.

This systematic review and network meta-analysis evaluated the efficacy of non-pharmacological interventions for anxiety, depression, and quality of life in individuals with substance use disorders (SUDs).

J Affect DisordMay 2, 2026Read summary
Clinical ResearchPulmonology

Effects of continuous positive airway pressure therapy on depression and anxiety in patients with obstructive sleep apnea with and without coronary heart disease.

This randomized controlled trial examined the effects of continuous positive airway pressure (CPAP) therapy on anxiety and depression in 72 patients with obstructive sleep apnea (OSA), both with and without coronary…

Heart LungMay 2, 2026Read summary
Clinical ResearchPsychiatry

Evidence for affective reorganization following two suicide-focused interventions delivered during massed cognitive processing therapy for PTSD.

This randomized controlled trial investigated the effects of crisis response planning (CRP) and safety planning (SP) on suicidal ideation in U.S. military personnel and veterans with PTSD.

J Affect DisordMay 1, 2026Read summary
Clinical ResearchInternal Medicine (General)

Effects of Lactiplantibacillus plantarum KABP051 Probiotic on Body Composition, Microbiome and Mood in Healthy Overweight Adults.

This randomized controlled trial evaluated the effects of Lactiplantibacillus plantarum KABP051 on body composition, microbiome, and mood in 60 healthy overweight adults over 12 weeks.

J Med FoodMay 1, 2026Read summary

April 20264

Clinical ResearchObstetrics & GynecologyOpen access

Comparing two posttraumatic stress disorder screening approaches to improve health outcomes in pregnant black women: a comparative effectiveness trial protocol.

This randomized controlled trial protocol aims to compare two PTSD screening approaches among Black pregnant women in urban obstetrics clinics.

Eur J PsychotraumatolApr 29, 2026Read summary
Clinical ResearchPsychiatry

Efficacy of digital cognitive behavioural therapy for insomnia in Armed Forces and Veteran populations - A systematic review and meta-analysis of randomised controlled trials.

This systematic review and meta-analysis evaluated the efficacy of digital cognitive behavioural therapy for insomnia (CBT-I) in Armed Forces personnel.

Sleep MedApr 29, 2026Read summary
Clinical ResearchPsychiatry

Mentalising impairments in somatic symptom and functional neurological disorders: A systematic review.

This systematic review examined mentalizing impairments in individuals with Somatic Symptom Disorder (SSD) and Functional Neurological Disorder (FND) compared to healthy and clinical controls.

J Psychosom ResApr 29, 2026Read summary
Clinical ResearchPsychiatryOpen access

The effects of group mentalization-based treatment-P on cognitive emotion regulation and tic symptoms in children with tic disorders.

This randomized controlled trial evaluated the impact of mentalization-based treatment-P on cognitive emotion regulation and tic symptoms in children with tic disorders.

Psychol PsychotherApr 29, 2026Read summary

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