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1333 articles
October 202624
Meta-analysis of Asymptomatic Monkeypox Virus Prevalence in Nonendemic Regions, 2022-2024.
This meta-analysis examined the prevalence of asymptomatic monkeypox virus (MPXV) detections in nonendemic regions from May 2022 to September 2024.
Meta-analysis of Maternal and Fetal Outcomes of Crimean-Congo Hemorrhagic Fever during Pregnancy.
This meta-analysis examined the maternal and fetal outcomes of Crimean-Congo hemorrhagic fever (CCHF) in 55 pregnancies. The study found a maternal mortality rate of 28.8% and a fetal loss rate of 57.4%.
HIV-associated pulmonary arterial hypertension: improving survival despite persistent treatment gaps - a systematic review and meta-analysis.
This systematic review and meta-analysis examined 12 cohorts of patients with HIV-associated pulmonary arterial hypertension (HIV-PAH), totaling 537 individuals.
A Systematic Review and Meta-Analysis of the Prevention and Management of Pediatric Urinary Tract Infection and Suspected Urinary Tract Infection: Technical Report.
This systematic review and meta-analysis evaluated management strategies for pediatric urinary tract infections (UTIs) in children without known anatomic anomalies, including antibiotic duration and route, and the use…
Tumor-Infiltrating Lymphocytes as a Predictor of Adjuvant Avelumab Efficacy in Patients with High-risk Triple-Negative Breast Cancer.
This phase III randomized controlled trial investigated the prognostic and predictive value of tumor-infiltrating lymphocytes (TIL) in 466 patients with high-risk early triple-negative breast cancer (TNBC) receiving…
Clinical Trial Protocol for LPS-Boost: Intensified [ 177 Lu]Lu-PSMA-617 Treatment for Patients with Metastatic Castration-Resistant Prostate Cancer with Low PSMA-Expressing Disease.
This multicenter, open-label phase 2 trial investigates an intensified treatment schedule of [177Lu]Lu-PSMA-617 for 45 patients with metastatic castration-resistant prostate cancer (mCRPC) and low PSMA expression.
Effects of Estriol-Lactobacilli Combination Versus Polycarbophil-Based Vaginal Moisturizer on Post-Radiation Vaginitis in Women With Cervical Cancer: A Randomized Controlled Trial.
This randomized controlled trial evaluated the efficacy of an estriol-lactobacilli combination vaginal tablet (E3/L) versus a polycarbophil-based vaginal moisturizer (PBVM) in 34 women with post-radiation vaginitis…
Prednisone in the Management of Pericarditis: A Systematic Review.
This systematic review evaluated the use of oral corticosteroids, primarily prednisone, in adults with acute or recurrent pericarditis.
Tumor and Organ Dose Estimates from 177 Lu-PSMA-617 Therapy in Patients with Metastatic Castration-Resistant Prostate Cancer: Results from the RESIST-PC Phase 2 Trial.
The RESIST-PC Phase 2 trial assessed dosimetry of [177Lu]Lu-PSMA-617 in patients with metastatic castration-resistant prostate cancer. A total of 48 patients were analyzed, receiving either 6.0 or 7.4 GBq per cycle.
"I Don't Speak English Well." Do Language Barriers Affect Automated External Defibrillator Use? A Randomized Simulation Study With Spanish-Speaking Laypeople.
This randomized controlled trial assessed the impact of language barriers on automated external defibrillator (AED) use among 50 Spanish-speaking university students.
Systematic Review and Meta-Analysis on Rescue Stenting for Large Vessel Occlusion Due to Underlying Intracranial Atherosclerotic Stenosis.
This systematic review and meta-analysis evaluated the efficacy and safety of rescue stent placement in patients with large vessel occlusion (LVO) due to intracranial atherosclerotic stenosis (ICAS).
Cost-Effectiveness of Adjunctive Middle Meningeal Artery Embolization for Chronic Subdural Hematoma: Secondary Analysis of EMBOLISE.
This secondary analysis of the EMBOLISE randomized trial evaluated the cost-effectiveness of adjunctive middle meningeal artery embolization (MMAE) versus evacuation surgery (ES) alone in 42 patients with chronic…
Volumetric Postcontrast T1 Turbo Spin-Echo vs Gradient-Recalled Echo MR Sequences for Detecting Brain Metastases: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the diagnostic performance of postcontrast 3D T1 Turbo Spin-Echo (TSE) versus Gradient-Recalled Echo (GRE) MRI sequences for detecting brain metastases in 544 patients.
Management of Antineutrophil Cytoplasmic Antibody-Associated Alveolar Hemorrhage: A Bayesian Reanalysis of the PEXIVAS Trial.
This Bayesian reanalysis of the PEXIVAS trial focused on adults with antineutrophil cytoplasmic antibody-associated vasculitis and diffuse alveolar hemorrhage (DAH).
Temporal Net Water Uptake Evolution and Its Association with Functional Outcome in Acute Ischemic Stroke.
This multicenter randomized controlled trial examined the relationship between temporal changes in net water uptake (NWU) and functional outcomes in 115 patients with acute ischemic stroke.
Evaluating CPR Breast Attachment Impact on EMT Training: A Randomized Controlled Trial.
This randomized controlled trial evaluated the impact of the ReviveHer breast attachment on EMT students' willingness and comfort in performing CPR on breasted and nonbreasted individuals.
Follow-Up 18F-Fluorodeoxyglucose Positron Emission Tomography in Treated Patients With Giant Cell Arteritis: A Systematic Review and Metaanalysis.
This systematic review and meta-analysis evaluated the use of 18F-fluorodeoxyglucose (FDG) PET to monitor disease activity in patients with large-vessel giant cell arteritis (LV-GCA) who showed clinical improvement…
Intrathecal Allogeneic B7-H3-Targeted CAR γδ T Cells for Leptomeningeal Metastasis from Solid Tumors: Safety, Efficacy, and Immunologic Dynamics in a Phase I Trial.
This phase I trial evaluated the safety and efficacy of intrathecal QH104, an allogeneic B7-H3-targeted CAR γδ T-cell therapy, in 3 patients with leptomeningeal metastasis from solid tumors.
[18F]RCCB6 PET/CT in Diagnosing Clear-Cell Renal Cell Carcinomas: A Prospective Comparison Study with [18F]FDG PET/CT and Conventional Imaging.
[18F]RCCB6 PET/CT was evaluated in a single-center phase II trial for detecting metastases in clear-cell renal cell carcinoma (ccRCC).
Ziftomenib with venetoclax and azacitidine for relapsed/refractory NPM1-mutated acute myeloid leukemia.
The KOMET-007 phase 1 trial evaluated the combination of ziftomenib with venetoclax and azacitidine in adults with relapsed/refractory NPM1-mutated acute myeloid leukemia (AML).
Health Economic & Implementation Determinants of Prehospital Stroke Triage Tools: A Systematic Review.
This systematic review evaluated health economic outcomes and implementation determinants of prehospital triage tools for suspected ischaemic stroke patients.
Primary care practitioners' experiences managing urinary tract infections: a qualitative evidence synthesis.
This qualitative evidence synthesis explored the experiences of primary care practitioners (PCPs) managing urinary tract infections (UTIs) across various international settings.
Osimertinib plus Gefitinib in Patients with EGFR-Mutated Advanced Non-Small Cell Lung Cancer and EGFR (C797X) Mutation Following First-Line Osimertinib: ORCHARD.
The ORCHARD study was a phase II trial assessing the efficacy of osimertinib plus gefitinib in patients with EGFR-mutated advanced non-small cell lung cancer (NSCLC) and EGFR C797X mutation after progression on…
Modified One Anastomosis Gastric Bypass (OAGB) Versus Duodenojejunostomy for Treatment of Superior Mesenteric Artery Syndrome: A Randomized Controlled Trial.
This randomized controlled trial compared modified one anastomosis gastric bypass (OAGB) to duodenojejunostomy in 20 patients with superior mesenteric artery syndrome.
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