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1034 articles

May 202611

Clinical ResearchNeurology

Mothership and Drip-and-Ship Strategies in Mechanical Thrombectomy for Acute Ischemic Stroke.

This systematic review and meta-analysis evaluated the effectiveness of mothership versus drip-and-ship strategies for acute ischemic stroke due to large vascular occlusion in 25,005 patients.

Ann Emerg MedMay 5, 2026Read summary
Clinical ResearchNeurologyOpen access

Prognostic Value of Natriuretic Peptides for Delayed Cerebral Ischemia and Outcomes After Aneurysmal Subarachnoid Hemorrhage: An Updated-Systematic Review and Meta-Analysis.

This systematic review and meta-analysis examined observational studies of natriuretic peptide (NP) levels measured within 7 days of aneurysmal subarachnoid hemorrhage (aSAH) and their association with delayed cerebral…

Neurocrit CareMay 5, 2026Read summary
Clinical ResearchNeurologyOpen access

Prophylactic Antiepileptic Drugs in Nontraumatic Intracerebral Hemorrhage: A Network Meta-Analysis.

This systematic review and Bayesian network meta-analysis compared prophylactic antiepileptic drugs (AEDs) with one another or control in adults with nontraumatic intracerebral hemorrhage (ICH).

Neurocrit CareMay 5, 2026Read summary
Clinical ResearchNeurology

Impact of Task-Oriented Training on Health Outcomes in Multiple Sclerosis: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis examined task-oriented training (TOT) for health outcomes in adults with multiple sclerosis, drawing on randomized controlled trials.

Am J Phys Med RehabilMay 5, 2026Read summary
Clinical ResearchNeurologyOpen access

Effectiveness of vestibular physical therapy on balance and dizziness in people with multiple sclerosis: A systematic review and meta-analysis.

This systematic review and meta-analysis assessed vestibular physical therapy (VPT) for balance and dizziness in people with multiple sclerosis (PwMS).

J Vestib ResMay 5, 2026Read summary
Clinical ResearchPhysical Medicine & Rehabilitation

Transcranial Direct Current Stimulation Combined With Balance Training for Chronic Ankle Instability: A Double-Blind, Pilot Randomized Controlled Trial.

This double-blind pilot randomized controlled trial evaluated whether active transcranial direct current stimulation (tDCS) added benefit to balance training in 19 individuals with chronic ankle instability.

J Sport RehabilMay 5, 2026Read summary
Clinical ResearchPediatricsOpen access

Global Pediatric Stroke Epidemiology: A Systematic Review of the Literature and Meta-Analysis.

This systematic review and meta-analysis assessed the global burden of pediatric stroke, revealing a birth prevalence of perinatal stroke at 21.01 per 100,000 total births and a childhood incidence of stroke at 3.73 per…

J Child NeurolMay 4, 2026Read summary
Case ReportInfectious DiseasesOpen access

Infliximab in a Child With Relapsing Tuberculous Meningoencephalitis: A Case Report and Literature Review.

A 5-year-old child with tuberculous meningoencephalitis experienced severe drug-induced hepatitis following standard antitubercular therapy, leading to the discontinuation of treatment.

Pediatr Infect Dis JMay 4, 2026Read case
Case ReportNeurology

Transcutaneous Spinal Cord Stimulation for Spasticity in Primary Lateral Sclerosis: A Case Series.

This case series involved six participants with primary lateral sclerosis (PLS) who underwent a single 30-minute session of transcutaneous spinal cord stimulation (tSCS).

J Neurol Phys TherMay 4, 2026Read case
Clinical ResearchNeurology

Reporting quality and evidence support in randomized controlled trials of Bupleurum-based herbal medicine formulas for epilepsy.

This meta-analysis evaluated the efficacy of Bupleurum-based herbal formulas in treating epilepsy, analyzing 33 randomized controlled trials with 2464 patients.

J EthnopharmacolMay 2, 2026Read summary
Clinical ResearchGeriatrics

Comparing the Effects of Cognitive and Physical Training on Cognitive Function and Brain Activation in People With Mild Cognitive Impairment and Mild Dementia: A Randomized Controlled Trial.

This randomized controlled trial evaluated the effects of cognitive training (CT) and physical training (PT) on cognitive function and brain activation in older adults with mild cognitive impairment or mild dementia.

Arch Phys Med RehabilMay 2, 2026Read summary

April 202613

Clinical ResearchNeurology

Efficacy and safety of Mudan granules for treatment of diabetic peripheral neuropathy: a multicenter, double-blind, placebo-controlled, randomized, clinical trial.

This multicenter, double-blind, placebo-controlled randomized trial evaluated the efficacy and safety of Mudan granules in 400 patients with diabetic peripheral neuropathy (DPN).

J EthnopharmacolApr 30, 2026Read summary
Clinical ResearchMedical Genetics

Clinical, Behavioral and Neuroradiological Phenotype in an Italian Cohort of Patients With Xia Gibbs Syndrome: A Multicenter Cross-Sectional Study and Systematic Literature Review.

This multicenter cross-sectional study examined 15 patients with Xia Gibbs Syndrome (XGS) due to heterozygous AHDC1 variants.

Am J Med Genet AApr 30, 2026Read summary
Case ReportMedical Genetics

FGF12-Related Early-Onset Epileptic Encephalopathies: Therapeutic Response to Sodium Channel Blockers.

Developmental and epileptic encephalopathies (DEEs) comprise a clinically and genetically heterogeneous group of severe neurodevelopmental disorders, frequently caused by pathogenic variants in genes encoding neuronal…

Am J Med Genet AApr 29, 2026Read case
Clinical ResearchNeurology

Effects of physical exercise on spasticity in people with multiple sclerosis: A systematic review.

This systematic review examined whether physical exercise reduces spasticity in people with multiple sclerosis (MS). It included 13 randomised controlled trials enrolling participants with EDSS scores ≤6.0 and…

PhysiotherapyApr 28, 2026Read summary
Case ReportMedical Genetics

Early-Onset Epileptic Encephalopathy and Neurodevelopmental Regression Associated With ST3GAL5 Deficiency.

A Turkish male infant presented with developmental delay and hypotonia, progressing to refractory epilepsy and neurodevelopmental regression.

Am J Med Genet AApr 27, 2026Read case
Clinical ResearchNeurology

The Efficacy of Proprioceptive Neuromuscular Facilitation-Based Robot-Assisted Therapy in Individuals With Stroke: A Randomized Controlled Trial.

This randomized controlled trial evaluated the effects of proprioceptive neuromuscular facilitation (PNF)-based robot-assisted therapy (RAT) on upper extremity motor performance, spasticity, activities of daily living…

Arch Phys Med RehabilApr 26, 2026Read summary
Clinical ResearchNeurologyOpen access

The effects of the PDE4 inhibitor roflumilast on cognitive performance after a cerebrovascular accident: a double-blind randomized placebo-controlled trial with an open label extension (ROSTMEMA).

This double-blind randomized placebo-controlled trial evaluated the effects of the PDE4 inhibitor roflumilast on cognitive performance in 100 post-stroke patients aged 41-70 with memory complaints.

J PsychopharmacolApr 24, 2026Read summary
Clinical ResearchNeurology

Prebiotics/synbiotics as natural alternatives for brain development and aging - focus on nutrigenomic and direct effects: a systematic review.

This systematic review examines the role of prebiotics and synbiotics in brain development and neurodegenerative diseases, analyzing 79 studies including human and animal research.

Nutr NeurosciApr 24, 2026Read summary
Clinical ResearchOtolaryngology (ENT)

Effects of Olfactory Training on Olfactory Bulb Volume Among Patients With Non-Sinonasal-Related Olfactory Dysfunction: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated the impact of olfactory training (OT) on olfactory bulb volume (OBV) in patients with non-sinonasal-related olfactory dysfunction.

Am J Rhinol AllergyApr 23, 2026Read summary
Clinical ResearchNeurology

Osteopathic manipulative treatment and cervicogenic headache: a randomized controlled trial.

This randomized controlled trial evaluated osteopathic manipulative treatment (OMT) for cervicogenic headache in 413 patients allocated to findings-based OMT or standardized sham treatment.

J Osteopath MedApr 23, 2026Read summary
Case ReportMedical Genetics

Tubulinopathy Case Series: Marked Intrafamilial Phenotypic Variability Associated With a Novel Missense TUBB Variant.

A family with a novel missense variant in the TUBB gene presented with significant intrafamilial phenotypic variability. The proband exhibited severe symptoms, including seizures and developmental delay from 6 months…

Am J Med Genet AApr 22, 2026Read case
Clinical ResearchGeriatrics

Care navigation for older adults after stroke - A systematic review and meta-analyses to guide social prescribing.

This systematic review and meta-analysis evaluated the impact of care navigation on anxiety, depression, quality of life, and well-being in older adults (60+) post-stroke.

Arch Gerontol GeriatrApr 21, 2026Read summary
Case ReportNeurologyOpen access

Neurological Puzzles After Radiotherapy: Mysterious Clues of Smart Syndrome, Two Case Reports.

This report discusses two patients who developed SMART syndrome, presenting with stroke-like symptoms and migraine-like headaches years after undergoing brain radiotherapy.

J Clin UltrasoundApr 21, 2026Read case

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