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1998 articles

October 202624

Case ReportNeurologyOpen access

Familial hypomagnesemia with secondary hypocalcemia: a novel TRPM6 mutation associated with treatment-resistant migraine in a North African family.

An 18-year-old woman from a consanguineous Moroccan family presented with lifelong hypomagnesemia and a severe migraine attack accompanied by paresthesias and muscle cramps.

Neurol SciOct 5, 2026Read case
Case ReportNephrology

When Infection Mimics Vasculitis: Hydralazine-Induced ANCA-Associated Crescentic Glomerulonephritis in the Setting of Active Infective Endocarditis.

A 58-year-old man with a history of bicuspid aortic valve presented with fatigue, anemia, and acute kidney injury. He was diagnosed with subacute infective endocarditis after blood cultures grew Streptococcus mutans.

Am J Case RepOct 5, 2026Read case
Clinical ResearchMedical GeneticsOpen access

A nationwide prospective randomized trial for diagnosing developmental disorders demonstrates genome sequencing outperforms standard of care.

This nationwide prospective randomized trial evaluated the diagnostic efficacy of genome sequencing (GS) compared to standard of care (SoC) in 567 individuals with unexplained developmental disorders (DD).

Genome MedOct 5, 2026Read summary
Clinical ResearchEndocrinology

Effects of rosehip (Rosa canina) supplementation on orthostatic intolerance symptoms in patients with type 2 diabetes: a randomized double-blind placebo-controlled clinical trial.

This randomized double-blind placebo-controlled trial investigated the effects of rosehip fruit extract on orthostatic intolerance symptoms in 60 adults with type 2 diabetes and orthostatic hypotension.

DaruOct 5, 2026Read summary
Clinical ResearchPreventive Medicine / Public Health

Fluid balance during hot-dry and warm-humid heat stress while adhering to occupational hydration recommendations.

This randomized controlled trial assessed fluid balance in 20 healthy adults during moderate-intensity work in hot-dry (HD) and warm-humid (WH) environments while following NIOSH hydration recommendations.

Ann Work Expo HealthOct 5, 2026Read summary
Clinical ResearchNeurologyOpen access

Electroacupuncture Targeting the NLRP3 Inflammasome in Senescence‑associated Cognitive Impairment: Mechanistic Synthesis and Meta‑analysis of Clinical Randomized Controlled Trials.

This meta-analysis reviewed nine randomized controlled trials involving 614 participants to evaluate the effects of electroacupuncture on senescence-associated cognitive impairment (SACI).

Neurochem ResOct 5, 2026Read summary
Clinical ResearchOncology (Medical)

A study on the intervention effect of a structured grief counseling program on grief responses in family caregivers of patients with advanced cancer.

This randomized controlled trial evaluated the impact of structured grief counseling on grief responses in family caregivers of advanced cancer patients.

Palliat Support CareOct 5, 2026Read summary
Case ReportEmergency Medicine

Ultrasound-Guided Disposition: Submersion Injury.

A 25-year-old male sustained an acute submersion injury due to water aspiration during snorkel training for U.S. Navy Search and Rescue Swimmer training.

J Spec Oper MedOct 5, 2026Read case
Clinical ResearchUrologyOpen access

Lymphocele After Radical Prostatectomy: A Systematic Review of Risk Factors and Quantitative Synthesis Preventive Strategies.

This systematic review evaluated risk factors and preventive strategies for lymphocele formation after radical prostatectomy with pelvic lymph node dissection.

World J UrolOct 5, 2026Read summary
Case ReportNephrologyOpen access

Nephrotic range proteinuria and rapid progression to end-stage kidney disease in seronegative pauci-immune necrotizing glomerulonephritis masked by cutaneous lesions: a case-based review.

A 22-year-old woman with a history of recurrent cutaneous lesions was hospitalized due to exacerbation of her skin condition. Laboratory tests revealed nephrotic-range proteinuria and reduced eGFR.

Rheumatol IntOct 5, 2026Read case
Clinical ResearchGastroenterology

Efficacy of Bifidobacterium animalis subsp. lactate BL-99 in relieving functional constipation: a randomized placebo-controlled clinical trial.

This randomized, double-blind, placebo-controlled trial evaluated the efficacy of Bifidobacterium animalis subsp. lactis BL-99 in 41 patients with functional constipation over 6 weeks.

Food FunctOct 5, 2026Read summary
Clinical ResearchEndocrinologyOpen access

Cardiovascular Morbidity and Mortality in Chronic Hypoparathyroidism: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated the cardiovascular risks associated with chronic hypoparathyroidism (HypoPT) in adults.

Calcif Tissue IntOct 5, 2026Read summary
Case ReportOtolaryngology (ENT)

Treatment of External Auditory Canal Hemangioma by Surgical Excision and Flap Reconstruction: 2 Case Reports.

Two cases of external auditory canal (EAC) hemangiomas are reported. The first case involved a 68-year-old man with a sensation of fullness in the left ear, while the second case involved a 62-year-old woman with…

Am J Case RepOct 5, 2026Read case
Clinical ResearchPediatrics

Serum ferritin in children with Attention Deficit Hyperactivity Disorder (ADHD): A systematic review and meta-analysis.

This systematic review and meta-analysis examined serum ferritin levels in children with Attention Deficit Hyperactivity Disorder (ADHD) compared to healthy controls.

PLoS OneOct 5, 2026Read summary
Clinical ResearchNeurology

Objective, long-term mobility data in patients with chronic pain after lumbar spine surgery treated with spinal cord stimulation-a prospective, multicenter trial.

This multicenter clinical trial evaluated the long-term effects of spinal cord stimulation (SCS) on mobility in 50 patients with chronic pain following lumbar spine surgery.

Reg Anesth Pain MedOct 5, 2026Read summary
Clinical ResearchPsychiatry

Efficacy of a Prescription-Based Mobile Digital Therapeutic as an Adjunct to Pharmacotherapy for the Acute Phase of Panic Disorder: Multicenter Randomized Controlled Trial.

This multicenter randomized controlled trial evaluated the efficacy of a prescription-based mobile digital therapeutic (DTx) as an adjunct to pharmacotherapy in 66 patients with acute-phase panic disorder.

J Med Internet ResOct 5, 2026Read summary
Clinical ResearchInfectious Diseases

Temporal proximity to counseling is associated with longitudinal bedaquiline and antiretroviral therapy adherence in multidrug-resistant tuberculosis and HIV treatment.

This randomized controlled trial examined the relationship between counseling session timing and medication adherence in 76 participants receiving treatment for multidrug-resistant tuberculosis (MDR-TB) and HIV in South…

PLoS OneOct 5, 2026Read summary
Clinical ResearchMedical Genetics

PHOENIX: a study protocol for a pilot randomised controlled trial of pre-emptive pharmacogenomic panel testing in acute care settings with health economic evaluations.

The PHOENIX trial is a pilot randomized controlled trial assessing the impact of pre-emptive pharmacogenomic panel testing on adverse drug reactions (ADRs) and treatment failures in acute care settings.

BMJ OpenOct 5, 2026Read summary
Clinical ResearchHematology

Efficacy and safety of erythrocytapheresis in chronic mountain sickness: a randomised controlled trial protocol (ESCAPE-CMS).

This randomized controlled trial protocol investigates the efficacy and safety of erythrocytapheresis in patients with chronic mountain sickness (CMS), a condition affecting over 4 million individuals at high altitudes.

BMJ OpenOct 5, 2026Read summary
Case ReportGeneral Surgery

Incidental discovery of a massive primary retroperitoneal serous cystadenoma following trauma.

A woman in her 70s presented with severe abdominal pain after a fall. Imaging revealed a massive cystic lesion in the left retroperitoneum, which was confirmed to be a ruptured cyst.

BMJ Case RepOct 5, 2026Read case
Clinical ResearchCardiology

Home-based neuro-cardiac rehabilitation in congenital heart disease: the QUALINEURO-REHAB trial study protocol.

The QUALINEURO-REHAB trial is a multicenter, two-arm randomized controlled trial assessing a home-based neuro-cardiac rehabilitation program in youth aged 8-25 with complex congenital heart disease (CHD).

BMJ OpenOct 5, 2026Read summary
Case ReportMedical Genetics

Coarctation of the aorta as the presenting cardiovascular manifestation of Williams syndrome in an infant.

A male infant presented for pre-operative evaluation of a left inguinal hernia, during which discrete juxtaductal coarctation of the aorta was incidentally found.

BMJ Case RepOct 5, 2026Read case
Case ReportPlastic Surgery

Boomerang-shaped extended latissimus dorsi flap for combined breast reconstruction and body contouring following massive weight loss.

A patient with a history of massive weight loss sought correction for her left-sided implant-based breast reconstruction, which had resulted in poor cosmetic outcomes and persistent pain.

BMJ Case RepOct 5, 2026Read case
Case ReportGastroenterology

Multisystem imaging findings as diagnostic red herrings in Wilson's disease.

A previously healthy man in his 20s presented with fever, cough, jaundice, and a right-sided pleural effusion. Initial tests revealed significant hepatic dysfunction, and imaging showed cirrhotic liver morphology…

BMJ Case RepOct 5, 2026Read case

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