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196 articles

September 202611

Case ReportNeurology

Life-threatening multisystem sarcoidosis with neurological, renal, ocular and autoimmune haemolytic manifestations treated with intravenous immunoglobulin, plasma exchange, cyclophosphamide and infliximab.

A patient with multisystem sarcoidosis presented with encephalopathy, acute tubulointerstitial nephritis, optic neuritis, and autoimmune hemolytic anemia, resembling a stroke.

BMJ Case RepSep 2, 2026Read case
Case ReportNephrology

Rapidly progressive glomerulonephritis in rheumatoid arthritis: an early presentation of ANCA-associated vasculitis.

A 68-year-old man with newly diagnosed seropositive rheumatoid arthritis presented with rapidly progressive glomerulonephritis just six months after his arthritis diagnosis.

BMJ Case RepSep 2, 2026Read case
Case ReportPediatrics

Recurrent incomplete Kawasaki disease with small-joint-predominant arthritis during the acute phase.

An adolescent boy presented on day 6 of illness with fever and left cervical lymphadenopathy, having a history of complete Kawasaki disease.

BMJ Case RepSep 2, 2026Read case
Clinical ResearchRheumatologyOpen access

SPOT: An Early Detection Tool for Predicting Pain Trajectories Following Intra-Articular Injections.

This randomized controlled trial aimed to identify 12-month pain trajectories in knee osteoarthritis (KOA) patients post-injection and develop a predictive model using patient-reported pain scores.

J Orthop ResSep 1, 2026Read summary
Clinical ResearchRheumatologyOpen access

Effectiveness of Yoga and Combined Exercise in Female With Rheumatoid Arthritis: Randomized Controlled Trial.

This randomized controlled trial evaluated the effects of yoga versus combined exercise on pain, balance, mobility, fatigue, depression, and quality of life in 74 females with rheumatoid arthritis in remission.

Musculoskeletal CareSep 1, 2026Read summary
Clinical ResearchRheumatology

Systematic review of fatigue assessment instruments for SLE: psychometric validation with COSMIN 2.0 guidelines.

This systematic review evaluated the psychometric properties of patient-reported outcome measures (PROMs) for fatigue in systemic lupus erythematosus (SLE) patients.

Rheumatology (Oxford)Sep 1, 2026Read summary
Clinical ResearchRheumatology

Classification performance of the 2023 ACR/EULAR antiphospholipid syndrome criteria: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the classification performance of the 2023 ACR/EULAR criteria for antiphospholipid syndrome (APS) across 24 studies.

Rheumatology (Oxford)Sep 1, 2026Read summary
Clinical ResearchRheumatology

Clinical and autoantibody associations with malignancy in systemic sclerosis: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated factors linked to malignancy in 27,624 patients with systemic sclerosis (SSc).

Rheumatology (Oxford)Sep 1, 2026Read summary
Clinical ResearchRheumatology

Systematic Literature Review Informing Paediatric Rheumatology European Society/Childhood Arthritis and Rheumatology Research Alliance-Endorsed Recommendations for the Treat-to-Target Strategy in Juvenile Dermatomyositis.

This systematic literature review aimed to evaluate evidence supporting the treat-to-target (T2T) strategy in managing juvenile dermatomyositis (JDM).

J RheumatolSep 1, 2026Read summary
Case ReportOphthalmology

COMBINATION OF METHOTREXATE AND MYCOPHENOLATE MOFETIL FOR REFRACTORY UVEITIS AND SCLERITIS: A Case SERIES.

This case series involved six patients, five with uveitis and one with scleritis, all of whom had treatment-resistant conditions.

Retin Cases Brief RepSep 1, 2026Read case
Clinical ResearchRheumatology

Efficacy and Safety of Ultra-Low Starting Dose Febuxostat Titration in Male Patients With Primary Gout.

This randomized controlled trial evaluated the efficacy and safety of initiating febuxostat at an ultra-low dose of 10 mg/day versus the standard 20 mg/day in 120 male patients with primary gout.

Int J Rheum DisSep 1, 2026Read summary

August 202613

Clinical ResearchRheumatology

Upadacitinib monotherapy versus methotrexate monotherapy in methotrexate-naïve Japanese patients with rheumatoid arthritis: Long-term efficacy and safety through 5 years in the SELECT-EARLY study.

This Phase III randomized controlled trial evaluated the long-term efficacy and safety of upadacitinib monotherapy versus methotrexate in methotrexate-naïve Japanese patients with rheumatoid arthritis over 5 years.

Mod RheumatolAug 31, 2026Read summary
Clinical ResearchRheumatology

Integrated safety analysis of filgotinib in Japanese patients with moderately to severely active rheumatoid arthritis over a treatment duration of up to 5 years.

This multicenter Phase III clinical trial evaluated the long-term safety of filgotinib in Japanese patients with moderately to severely active rheumatoid arthritis over a treatment duration of up to 5 years.

Mod RheumatolAug 31, 2026Read summary
Clinical ResearchRheumatology

Inebilizumab treatment in Japanese patients with IgG4-related disease: A subgroup analysis of a randomized, double-blind, placebo-controlled, phase 3 trial (MITIGATE).

This subgroup analysis of the MITIGATE study evaluated the efficacy and safety of inebilizumab in 27 Japanese patients with IgG4-related disease.

Mod RheumatolAug 31, 2026Read summary
Clinical ResearchRheumatology

Impact of anti-drug antibodies and neutralising antibodies on safety and efficacy of ozoralizumab in rheumatoid arthritis.

This analysis of participants in the phase II/III OHZORA trial (ozoralizumab with methotrexate) and phase III NATSUZORA trial (without methotrexate) assessed antidrug antibodies (ADAs), neutralising antibodies (NAbs)…

Mod RheumatolAug 31, 2026Read summary
Case ReportMedical Genetics

Digital Acro-osteolysis Revealing Hajdu-Cheney Syndrome in an Elderly Patient: A Case Report.

An 85-year-old woman presented with infectious dactylitis of the right third finger. Radiographic examination revealed distal osteolysis in multiple digits.

J Hand Surg Asian Pac VolAug 31, 2026Read case
Case ReportHematology

VEXAS Syndrome:Report of One Case.

An elderly male presented with fatigue and fever, later developing macrocytic anemia, tracheal and bronchial wall thickening, polyarthritis, rashes, and elevated inflammatory markers.

Zhongguo Yi Xue Ke Xue Yuan Xue BaoAug 30, 2026Read case
Clinical ResearchRheumatology

Association of neutrophil-to-lymphocyte ratio with disease activity in systemic lupus erythematosus: A meta-analysis.

This meta-analysis evaluated the relationship between the neutrophil-to-lymphocyte ratio (NLR) and disease activity in systemic lupus erythematosus (SLE) among 4,006 SLE patients and 2,576 healthy controls.

LupusAug 23, 2026Read summary
Clinical ResearchRheumatologyOpen access

Evidence-based guidelines for the diagnosis and management of adult-onset IgA vasculitis.

This systematic review presents evidence-based guidelines for the diagnosis and management of adult-onset IgA vasculitis (IgAV), a rare condition with a poorer prognosis compared to childhood-onset.

Nat Rev RheumatolAug 20, 2026Read summary
Clinical ResearchDermatologyOpen access

Placebo Response in Randomised Controlled Trials of Systemic Therapies for Cutaneous Lupus Erythematosus: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis examined placebo responses in randomized controlled trials of systemic therapies for cutaneous lupus erythematosus (CLE).

Pharmaceut MedAug 18, 2026Read summary
Clinical ResearchRheumatology

Timing of OMERACT core domain measurement in gout clinical trials: a systematic review of randomised trials.

This systematic review evaluated the timing and reporting of core domain measurements in 43 randomized trials of urate-lowering therapy and gout flares.

Semin Arthritis RheumAug 18, 2026Read summary
Case ReportInfectious Diseases

Disseminated Nocardia pseudobrasiliensis infection in a case of juvenile systemic lupus erythematosus on immunosuppressive therapy.

A juvenile patient with systemic lupus erythematosus on immunosuppressive therapy developed disseminated Nocardia pseudobrasiliensis infection, presenting as necrotizing pneumonia, subcutaneous nodules, and a central…

LupusAug 16, 2026Read case
Clinical ResearchOncology (Medical)

From human papillomavirus (HPV) infection to HPV-associated cancers in systemic lupus erythematosus: A systematic review and Meta-analysis.

This systematic review and meta-analysis evaluated the risk of HPV infection and associated cancers in patients with systemic lupus erythematosus (SLE).

Prev MedAug 11, 2026Read summary
Case ReportInfectious DiseasesOpen access

Tuberculous Arthritis Diagnosed by Metagenomic Sequencing after Negative Microbiology Studies and a 4-Year Delay.

A 70-year-old man receiving treatment for lung cancer had chronic left knee pain and recurrent swelling. Two arthroscopic procedures were performed, but repeated standard tuberculosis tests were negative.

Am J Trop Med HygAug 11, 2026Read case

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