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1845 articles
July 202624
Efficacy of anti-GD2 antibody immunotherapy with filgrastim and teceleukin versus standard treatment with sargramostim, aldesleukin and isotretinoin in children with high-risk neuroblastoma.
This randomized controlled trial evaluated the efficacy of an alternative immunotherapy regimen (G-CSF/teceleukin) versus a standard regimen (GM-CSF/aldesleukin/isotretinoin) in children with high-risk neuroblastoma.
Prospective comparison of [ 68 Ga]Ga-FAPI-04 PET/MRI, [ 18 F]FDG PET/CT, and contrast-enhanced MRI for predicting pathologic complete response after neoadjuvant chemotherapy in breast cancer.
This prospective single-center study evaluated the effectiveness of [68Ga]Ga-FAPI-04 PET/MRI, [18F]FDG PET/CT, and contrast-enhanced MRI in predicting pathologic complete response (pCR) after neoadjuvant chemotherapy in…
Immune checkpoint inhibitor-based chemotherapy for granulocyte-colony stimulating factor-producing advanced esophageal squamous cell carcinoma: a report of three cases.
Three men with advanced granulocyte-colony stimulating factor (G-CSF)-producing esophageal squamous cell carcinoma received fluorouracil, cisplatin, and pembrolizumab.
More Prominent 18 F-FDG Uptake Than 68 Ga-FAPI-04 in Nongestational Choriocarcinoma.
A 56-year-old man was found to have nongestational choriocarcinoma of unknown primary with multiple metastases. On PET/CT, the lesions showed intense 18F-FDG uptake but limited accumulation of 68Ga-FAPI-04.
Adrenocortical oncocytoma manifesting as primary aldosteronism: a case report.
A 44-year-old man presented with severe hypertension and hypokalaemia, revealing a right adrenal lesion on imaging. Evaluation confirmed primary aldosteronism, with adrenal venous sampling indicating right-sided…
Validation of the lung immune prognostic index in extensive-stage small cell lung cancer: Post hoc analysis of the caspian and IMpower133 phase 3 trials.
This validation study assessed the Lung Immune Prognostic Index (LIPI) in extensive-stage small cell lung cancer (ES-SCLC) using data from the CASPIAN and IMpower133 phase III trials.
Primary Osteosarcoma of the First Metatarsal With Multiple Metastases on 18F-FDG PET/CT.
A patient presented with primary osteosarcoma located in the first metatarsal, an uncommon site for this type of tumor. Imaging with 18F-FDG PET/CT revealed multiple metastases, which were later confirmed through…
Effectiveness of enhanced recovery after surgery among cancer patients: A meta-analysis of randomized controlled trials.
This meta-analysis of randomized controlled trials evaluated the effectiveness of enhanced recovery after surgery (ERAS) in cancer patients.
A systematic review of economic evidence of artificial intelligence in healthcare.
This systematic review evaluated the economic evidence of artificial intelligence (AI) technologies in healthcare, analyzing 98 unique evaluations from 91 records.
Primary Cutaneous Follicular Helper T-Cell Lymphoma: A Clinicopathological Study of Six Cases and Review of the Literature.
This study presents six cases of primary cutaneous follicular helper T-cell lymphoma (pcTFH-L), characterized by localized skin lesions in patients aged 42 to 75 years, without systemic symptoms.
primary analysis of the RANDOMIZED eortc-2139/columbus-ad trial: Adjuvant encorafenib and binimetinib versus placebo in high-risk stage II BRAF-V600E/K melanoma.
The EORTC 2139 - Columbus-AD trial evaluated the efficacy and safety of adjuvant therapy with encorafenib and binimetinib versus placebo in patients with resected high-risk stage IIB/C BRAF V600E/K melanoma.
Polysaccharides-mediated mitochondrial remodeling: role in chemotherapy resistance of gastrointestinal tumors.
This systematic review examined the role of mitochondrial remodeling in chemotherapy resistance in gastrointestinal (GI) tumors and evaluated the potential of polysaccharides as therapeutic agents.
A novel MYO5C-ALK fusion in lung adenocarcinoma: limited alectinib response and durable lorlatinib benefit.
A 72-year-old never-smoker with stage IVB lung adenocarcinoma was found to have a novel MYO5C-ALK fusion. Despite initial treatment with alectinib, the tumor progressed after approximately seven months without any…
Deep learning approaches for predicting response to neoadjuvant chemotherapy in muscle invasive bladder cancer: A systematic review.
This systematic review evaluated deep learning models for predicting neoadjuvant chemotherapy response in muscle-invasive bladder cancer (MIBC).
Financial factors shaping treatment decisions in oncology: A systematic review.
This systematic review examined how financial factors influence treatment decisions in oncology, analyzing 60 studies. It found that financial incentives, particularly from industry, significantly affect prescribing…
Systematic review of antiemetic therapy for low emetogenic chemotherapy: comparing 5-HT 3 receptor antagonists and dexamethasone.
This systematic review evaluated the comparative effectiveness of 5-HT3 receptor antagonists versus dexamethasone for preventing chemotherapy-induced nausea and vomiting in adult patients receiving low-emetogenic…
Genomic Diversity and Clinical Variability in Pediatric Primary Cutaneous Anaplastic Large Cell Lymphoma: A Case Series.
Three pediatric patients with primary cutaneous anaplastic large cell lymphoma (pcALCL) presented with skin-limited disease. They exhibited significant molecular heterogeneity, including known and novel gene fusions.
Long-term safety and efficacy of ponesimod, an oral S1P1 receptor modulator, in relapsing-remitting multiple sclerosis (RRMS): Results from randomized phase 2b core and extension studies spanning up to 13 years.
This study evaluated the long-term safety and efficacy of ponesimod in patients with relapsing-remitting multiple sclerosis (RRMS) over a period of up to 13 years, utilizing data from a randomized phase 2b trial and its…
The impact of different types of play interventions on anxiety and depressive symptoms in children with cancer: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the effects of play interventions on anxiety and depressive symptoms in 1541 children with cancer.
Iodine Avid Muscle Metastases Mimicking Skeletal Lesions on Whole-Body Iodine Scan in Poorly Differentiated Thyroid Carcinoma -SPECT/CT to the Rescue.
A patient with poorly differentiated thyroid carcinoma (PDTC) presented with multifocal muscle metastases that were iodine-avid, leading to confusion with skeletal lesions on whole-body iodine scans.
Endoscopic Salvage Following Radiotherapy for Oesophageal Cancer: A Systematic Review.
This systematic review evaluated the safety and efficacy of endoscopic salvage procedures following definitive chemoradiotherapy (dCRT) for locally advanced oesophageal squamous cell carcinoma (OSCC) and adenocarcinoma…
Minimally Invasive Remote Approaches Versus Conventional Open Approach in Central Neck Dissection for Patients Undergoing Total Thyroidectomy: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis compared minimally invasive remote approaches (MIRA) to conventional open approaches (COA) for central neck dissection during total thyroidectomy in thyroid cancer patients.
Severe Veno-Occlusive Disease in a Child With Wilms Tumor: Acute Management and Subsequent Bridging With Irinotecan Treatment.
A pediatric patient with Wilms tumor developed severe hepatic veno-occlusive disease (VOD) following treatment with dactinomycin and vincristine.
Multiple myeloma diagnosed after contrast-enhanced computed tomography without renal complications: a case report with literature review.
A 77-year-old woman presented with numbness of the right lower lip, leading to a panoramic radiography that revealed a radiolucent lesion in the right mandible.
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