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1998 articles

October 202624

Clinical ResearchOncology (Medical)Open access

A Phase I Study of PF-07062119, an Anti-GUCY2C/Anti-CD3 Bispecific Fc Antibody, in Patients with Advanced Gastrointestinal Cancers.

This Phase I multicenter study evaluated PF-07062119, an anti-GUCY2C/anti-CD3 bispecific antibody, in 79 patients with advanced gastrointestinal cancers.

Cancer Res CommunOct 1, 2026Read summary
Case ReportEndocrinology

Insights into diagnosis and management of giant adrenal pseudocysts.

A young man presented with headaches and mild anaemia, leading to imaging that revealed a giant left adrenal cystic lesion measuring 19×15×15 cm. Despite indeterminate CT findings, PET imaging suggested a benign nature.

BMJ Case RepOct 1, 2026Read case
Case ReportOncology (Medical)

From Genomic Insight to Clinical Impact: Dramatic Response in RET Fusion-positive Pancreatic Cancer.

A 48-year-old woman with pancreatic ductal adenocarcinoma and liver metastases experienced a significant response to selpercatinib after genomic profiling revealed an NCOA4-RET fusion.

Anticancer ResOct 1, 2026Read case
Clinical ResearchInfectious Diseases

Pharmacokinetics, Immunogenicity, and Safety of a Modified YTE Antibody in Healthy Adults.

This Phase I randomized controlled trial evaluated the pharmacokinetics, immunogenicity, and safety of REGN17092, a modified YTE antibody targeting SARS-CoV-2, in 40 healthy adults.

Clin Pharmacol Drug DevOct 1, 2026Read summary
Clinical ResearchGastroenterology

Enhanced recovery after colorectal surgery in patients with inflammatory bowel disease to reduce hospital length of stay: A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the impact of enhanced recovery after surgery (ERAS) protocols on adult patients with inflammatory bowel disease (IBD).

Colorectal DisOct 1, 2026Read summary
Case ReportGastroenterology

Gastric neuroendocrine tumours after prolonged proton pump inhibitor use.

A woman in her 40s with chronic gastro-oesophageal reflux disease had been on proton pump inhibitors for 20 years. She was diagnosed with gastric neuroendocrine tumours during an upper endoscopy.

BMJ Case RepOct 1, 2026Read case
Clinical ResearchOncology (Medical)

A Phase I Study of Nimotuzumab Combined with Irinotecan in Chinese Patients with Advanced Solid Tumors.

This Phase I study assessed the pharmacokinetics and safety of nimotuzumab combined with irinotecan in Chinese patients with advanced solid tumors.

Clin Pharmacol Drug DevOct 1, 2026Read summary
Case ReportOncology (Medical)

Well-differentiated SMARCB1-deficient Pancreatic Malignancy With Indolent Liver Metastases.

A 66-year-old woman underwent distal pancreatectomy for a pancreatic tail malignancy, later developing liver metastases six years post-surgery.

Anticancer ResOct 1, 2026Read case
Case ReportNeurosurgery

The Urgent Surgical Outcome of Intracranial Subdural Empyema: A Case Presentation.

A patient presented unconscious due to intracranial subdural empyema, a severe brain infection. Urgent surgical intervention was performed, leading to a rapid recovery postoperatively.

Mymensingh Med JOct 1, 2026Read case
Clinical ResearchOncology (Medical)

Intermittent Pneumatic Compression in Patients with Postmastectomy Lymphedema: A Randomized Controlled Trial.

This randomized controlled trial evaluated the effects of intermittent pneumatic compression (IPC) combined with exercises on upper limb lymphedema in 21 patients post-mastectomy.

Mymensingh Med JOct 1, 2026Read summary
Case ReportOncology (Medical)

Multidisciplinary Treatment With Repeated Thermal Ablation for Multisite Metastatic Colon Cancer in an Elderly Patient.

An 81-year-old woman with a history of myocardial and cerebral infarctions presented with metastatic colon cancer, including multiple liver and ovarian metastases.

Anticancer ResOct 1, 2026Read case
Case ReportGeneral Surgery

Temporary Mesocaval Bypass During Pancreaticoduodenectomy for Pancreatic Cancer With Portal Vein Occlusion: A Case Report.

A 79-year-old man with locally advanced pancreatic cancer and complete portal vein occlusion underwent pancreaticoduodenectomy after showing a favorable response to preoperative therapy.

Anticancer ResOct 1, 2026Read case
Clinical ResearchGeriatrics

Association of Sarcopenia With Global, Motor, Cognitive, and Swallowing Function Prognosis in Stroke Patients: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated the impact of sarcopenia on functional outcomes in stroke patients. Analyzing 36 cohort studies, it found that patients with sarcopenia had a significantly higher risk…

Brain BehavOct 1, 2026Read summary
Clinical ResearchGeneral Surgery

Surgical Resection of Metachronous Liver Metastases in Non-colorectal Non-neuroendocrine Gastrointestinal Cancers: Systematic Review and Meta-analysis.

This systematic review and meta-analysis evaluated the impact of surgical resection on overall survival in patients with metachronous liver metastases from non-colorectal non-neuroendocrine gastrointestinal cancers.

Anticancer ResOct 1, 2026Read summary
Clinical ResearchNephrology

Mediation Analysis of Urine Osmolality and Response to Tolvaptan in Autosomal Dominant Polycystic Kidney Disease: A Post Hoc Assessment.

This post hoc analysis of the TEMPO 3:4 randomized controlled trial evaluated urine osmolality (Uosm) as a biomarker for long-term response to tolvaptan in patients with autosomal dominant polycystic kidney disease…

Nephrology (Carlton)Oct 1, 2026Read summary
Clinical ResearchOncology (Medical)

Giredestrant plus Everolimus in Advanced Breast Cancer.

This phase 3 randomized controlled trial evaluated the efficacy of giredestrant plus everolimus versus standard endocrine therapy plus everolimus in patients with ER-positive, HER2-negative advanced breast cancer who…

N Engl J MedOct 1, 2026Read summary
Clinical ResearchOncology (Medical)

Efficacy and Safety of PD-1/PD-L1 Inhibitors Combined With Anti-Angiogenic Tyrosine Kinase Inhibitors for Recurrent or Metastatic Nasopharyngeal Carcinoma: A Systematic Review and Single-Arm Meta-Analysis.

This systematic review and meta-analysis evaluated the efficacy and safety of PD-1/PD-L1 inhibitors combined with anti-angiogenic tyrosine kinase inhibitors in 357 patients with recurrent or metastatic nasopharyngeal…

Cancer MedOct 1, 2026Read summary
Case ReportMedical Genetics

Alpha-catenin Mutation-associated Synchronous Follicular Thyroid Carcinoma and Papillary Thyroid Carcinoma With Numerous Adenomatoid Nodules.

A 59-year-old woman with a history of breast cancer was found to have a thyroid nodule during a chest CT. Subsequent biopsies revealed synchronous minimally invasive follicular thyroid carcinoma and classic papillary…

Anticancer ResOct 1, 2026Read case
Case ReportOncology (Medical)

Mastectomy and sentinel lymph node biopsy in a patient with left-sided breast cancer and Poland syndrome.

An elderly woman with left-sided Poland syndrome presented with breast cancer detected during routine imaging for malignant melanoma.

BMJ Case RepOct 1, 2026Read case
Case ReportInfectious Diseases

Human Infection with Japanese Encephalitis Virus Genotype V, China, 2025.

A human case of Japanese encephalitis virus genotype V (JEV GV) was confirmed in China through serological testing, sequencing, and quantitative reverse transcription PCR.

Emerg Infect DisOct 1, 2026Read case
Case ReportNeurology

Clinical Reasoning: A 13-Year-Old Boy With Acute-Onset Generalized Dystonia, Rostrocaudal Gradient, and Severe Bulbar Dysfunction.

A 13-year-old boy presented with acute-onset generalized dystonia, characterized by progressive slowness, speech loss, dysphagia, rigidity, and dystonic posturing over a month.

NeurologyOct 1, 2026Read case
Case ReportDermatology

Paraneoplastic dermatomyositis preceding detection of metastatic oesophageal squamous cell carcinoma after prolonged remission following pembrolizumab therapy.

A man in his late fifties with a history of treated oesophageal squamous cell carcinoma developed severe dermatomyositis after six years of remission.

BMJ Case RepOct 1, 2026Read case
Case ReportNeurosurgery

A Mysterious Case of Giant Scalp Devil's Horn with Intracranial Extension Removed by Surgical Excision.

A 60-year-old male presented with altered consciousness, chronic headaches, blurred vision, and scalp swelling. Imaging revealed a giant cutaneous horn in the scalp with underlying bony erosion and intracranial…

Mymensingh Med JOct 1, 2026Read case
Case ReportInfectious Diseases

Chlamydia psittaci Meningitis, Chile, 2023.

A 50-year-old farm worker in Chile presented with meningitis, which was confirmed to be caused by Chlamydia psittaci through cerebrospinal fluid quantitative real-time PCR and serology.

Emerg Infect DisOct 1, 2026Read case

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