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1845 articles

June 202620

Clinical ResearchGeneral SurgeryOpen access

Preoperative risk factors for postoperative pneumonia in patients with esophageal cancer: A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated preoperative risk factors for postoperative pneumonia in patients undergoing esophagectomy for esophageal cancer.

Surg TodayJun 3, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Is there a role for early SSTR-targeting PRRT in GEP-NET?

Peptide receptor radionuclide therapy (PRRT) with radiolabelled somatostatin analogues, such as [¹⁷⁷Lu]Lu-DOTATATE, is approved as a second-line treatment for progressive, gastroenteropancreatic neuroendocrine tumors…

Eur J Nucl Med Mol ImagingJun 3, 2026Read summary
Clinical ResearchOncology (Medical)Open access

CXCR4-targeted [ 68 Ga]Ga-PentixaFor PET/CT improves staging and alters management in marginal zone lymphoma: a prospectively recruited head-to-head study with [ 18 F]FDG.

[ 68 Ga]Ga-PentixaFor PET/CT was evaluated in a prospective study of 41 treatment-naïve patients with marginal zone lymphoma (MZL) to compare its effectiveness against [ 18 F]FDG.

Eur J Nucl Med Mol ImagingJun 3, 2026Read summary
Clinical ResearchDermatology

Clinical Outcomes and Prognostication of CRTC1::TRIM11 Fusion Cutaneous Tumors.

Since the original description of CRTC1::TRIM11 fusion cutaneous tumors (CTCT) in 2018, an increasing number of cases with metastatic behavior have been reported, yet there are limited studies analyzing prognostic…

Am J Surg PatholJun 3, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Prognostic Value of Circulating Tumor DNA-Based Minimal Residual Disease for Recurrence-Free Survival in Resectable Gastric Cancer: A Systematic Review and Meta-Analysis with Serial Monitoring Analysis.

This systematic review and meta-analysis evaluated the prognostic value of circulating tumor DNA (ctDNA)-based minimal residual disease (MRD) in 520 patients with resectable gastric cancer.

Dig Dis SciJun 3, 2026Read summary
Clinical ResearchOncology (Medical)

Beyond ATRX: The heterogeneous basis of Alternative Lengthening of Telomeres in osteosarcoma.

This systematic review examined the prevalence of the alternative lengthening of telomeres (ALT) in osteosarcoma using patient-derived samples and genomic datasets.

Cancer GenetJun 2, 2026Read summary
Case ReportRadiology (Diagnostic)

More Impressive 18 F-FDG PET/CT Findings Than 68 Ga-DOTA-FAPI-04 in a Cervical Chordoma.

An 81-year-old woman presented with a cervical chordoma affecting the C1-C5 vertebrae. Imaging revealed significant 18 F-FDG uptake, contrasting with minimal accumulation of 68 Ga-DOTA-FAPI-04.

Clin Nucl MedJun 2, 2026Read case
Clinical ResearchOncology (Medical)

Gut microbiome dysbiosis and cancer: A systematic review on the emerging role of probiotics in oncology.

This systematic review evaluated the impact of probiotic supplementation in cancer patients, focusing on its clinical effects.

Crit Rev Oncol HematolJun 2, 2026Read summary
Clinical ResearchOncology (Medical)

Efficacy of Esomeprazole Cream in Preventing Radiation-Induced Dermatitis in Cancer Patients.

This randomized controlled trial evaluated the efficacy of 2% esomeprazole cream in preventing radiation-induced dermatitis (RID) in 36 patients with head and neck cancer.

J Pain Symptom ManageJun 2, 2026Read summary
Clinical ResearchAnesthesiology

Impact of Intravenous Lidocaine, Dexmedetomidine, and Intrathecal Morphine on Metastasis-Related Biomarkers and Cellular Immune Profiles in Colorectal Surgery: A Prospective, Randomized Controlled Trial.

This prospective, randomized controlled trial evaluated the effects of intravenous lidocaine, dexmedetomidine, and intrathecal morphine on metastasis-related biomarkers and immune profiles in 114 adults undergoing…

Anesth AnalgJun 2, 2026Read summary
Clinical ResearchOphthalmology

Cancer and glaucoma: A systematic review.

This systematic review examined the relationship between glaucoma and cancer, analyzing 44 studies. It found that 18 studies reported increased glaucoma prevalence in cancer patients, while 15 studies indicated that…

Eur J OphthalmolJun 2, 2026Read summary
Clinical ResearchOtolaryngology (ENT)Open access

Sentinel Node Biopsy in the Neck Management of cN0 Sinonasal Squamous Cell Carcinoma: A Multicenter Pilot Trial on Safety and Feasibility.

This prospective, single-arm, open-label, multicentre phase II pilot trial assessed the safety and feasibility of sentinel node biopsy (SNB) in patients with clinically node-negative sinonasal squamous cell carcinoma.

Ann Surg OncolJun 2, 2026Read summary
Clinical ResearchOncology (Medical)

Intismeran Autogene Plus Pembrolizumab Versus Pembrolizumab Alone in High-Risk Resected Melanoma: 5-Year Update of the Randomized Phase IIb KEYNOTE-942 Study.

The phase IIb KEYNOTE-942 study evaluated the efficacy of intismeran autogene plus pembrolizumab compared to pembrolizumab alone in patients with resected stage IIIB to IV melanoma.

J Clin OncolJun 1, 2026Read summary
Clinical ResearchHematology

Acquired ring chromosomes in hematological malignancies: A systematic evidence review for diagnostic advances, cytogenomic insights, and clinical significance by an International Consortium on Human Ring Chromosomes (ICHRC) working group.

This systematic review by the International Consortium on Human Ring Chromosomes (ICHRC) examines acquired ring chromosomes (aRCs) in hematological malignancies.

Cancer GenetJun 1, 2026Read summary
Clinical ResearchNeurosurgery

Intraoperative technologies in high grade glioma surgery: strategic implementation for Asia-Pacific centers.

This systematic review evaluated intraoperative technologies for high grade glioma (HGG) surgery in Asia-Pacific centers. It found that while neuronavigation and awake craniotomy with brain mapping are essential…

J Clin NeurosciJun 1, 2026Read summary
Case ReportOtolaryngology (ENT)Open access

Intranasal verrucous carcinoma with autoinoculation from benign warts in the context of locus minoris resistentiae.

A 50-year-old male presented with verrucous carcinoma in the left nasal vestibule, likely arising from autoinoculation of HPV from a prior facial wart at the site of nasal trauma.

Wien Med WochenschrJun 1, 2026Read case
Case ReportPathology (Anatomic & Clinical)Open access

Metaplastic-Like and Squamous Cell Carcinoma-Like Cells in Liquid-Based Cytology Associated With Small Cell Neuroendocrine Carcinoma of the Uterine Cervix.

Metaplastic-like cells exhibit an eccentric nucleus. SCC-like cells are planar aggregates with prominent atypical nuclei, similar to SCCs.

CytopathologyJun 1, 2026Read case
Clinical ResearchOncology (Medical)Open access

Final outcomes of the SOFT and TEXT phase III trials in premenopausal hormone receptor-positive early breast cancer.

The SOFT and TEXT phase III trials evaluated the long-term outcomes of ovarian function suppression (OFS) combined with tamoxifen or exemestane in premenopausal women with hormone receptor-positive early breast cancer.

Ann OncolJun 1, 2026Read summary
Clinical ResearchRadiology (Diagnostic)

Informing the Measurement of Timely Follow-Up on Inconclusive or Abnormal Screening Mammograms: An Environmental Scan.

This environmental scan reviewed current standards for timely follow-up after inconclusive or abnormal screening mammograms, analyzing 12 guidelines, 23 peer-reviewed articles, and 5 measures.

Jt Comm J Qual Patient SafJun 1, 2026Read summary
Case ReportOncology (Medical)Open access

Head and neck NUT carcinoma-radiotherapy dose, chemotherapy choice, and outcomes: lessons from a 7-year complete remission.

A 19-year-old male with locally advanced supraglottic NUT carcinoma presented with dysphagia and otalgia. After laser debulking and temporary tracheostomy, he received induction chemotherapy with cisplatin, doxorubicin…

Strahlenther OnkolJun 1, 2026Read case

May 20264

Case ReportGastroenterology

Contrast-Enhanced Ultrasound Successfully Diagnoses a Rare Case of Coexisting Colorectal Cancer Liver Metastasis and Hepatocellular Carcinoma: A Case Report.

A 57-year-old Asian male presented with a rectal mass and multiple distinct liver lesions. Contrast-enhanced ultrasound (CEUS) suggested the presence of both colorectal cancer liver metastasis and hepatocellular…

J Clin UltrasoundMay 31, 2026Read case
Clinical ResearchRadiology (Diagnostic)Open access

Comparison of abbreviated MRI and ultrasonography in the detection of early hepatocellular carcinoma: a meta-analysis.

This meta-analysis compared abbreviated magnetic resonance imaging (AMRI) with ultrasonography (US) for detecting early-stage hepatocellular carcinoma. Nine studies involving 1,914 participants were included.

Clin Transl OncolMay 31, 2026Read summary
Clinical ResearchNeurology

Artificial intelligence based techniques for brain tumor analysis: A systematic review.

This systematic review evaluates artificial intelligence techniques for brain tumor analysis, focusing on segmentation and classification methods. Out of 3950 sourced papers, 101 met the inclusion criteria.

Artif Intell MedMay 30, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Phase 1 dose-escalation trial combining sulfasalazine and stereotactic radiosurgery in patients with recurrent glioblastoma.

This Phase I dose-escalation trial investigated the safety and efficacy of sulfasalazine combined with stereotactic radiosurgery (SRS) in patients with recurrent glioblastoma.

Redox BiolMay 30, 2026Read summary

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