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1845 articles

May 202624

Case ReportNephrology

Histotripsy-Induced Acute Kidney Injury Following Liver Tumor Treatment: A Preliminary Report of 9 Cases.

This report details nine patients who developed acute kidney injury (HAKI) following histotripsy treatment for liver tumors.

J Vasc Interv RadiolMay 30, 2026Read case
Clinical ResearchOncology (Medical)Open access

Pilot Randomized Trial of a Supportive Care Intervention for Patients With Locally Advanced Rectal Cancer.

This pilot randomized controlled trial evaluated the feasibility and acceptability of the PATHWAYS supportive care intervention for patients starting multimodality therapy for locally advanced rectal cancer (LARC).

J Pain Symptom ManageMay 30, 2026Read summary
Case ReportOncology (Medical)

Infrahepatic IVC Resection and Prosthetic Reconstruction for Renal Cell Carcinoma.

A 50-year-old man with right renal cell carcinoma (RCC) presented with level II venous tumor thrombus (VTT) and underwent radical nephrectomy along with en bloc infrahepatic inferior vena cava (IVC) resection due to…

Am SurgMay 30, 2026Read case
Clinical ResearchOncology (Medical)

A randomized phase III trial of anthracyclines followed by taxane versus taxane plus carboplatin as (neo)adjuvant therapy in patients with triple-negative breast cancer: KCSG BR 15-1 PEARLY trial.

The PEARLY trial, a multicenter randomized phase III study, evaluated the addition of carboplatin to standard anthracycline and taxane therapy in patients with early-stage triple-negative breast cancer (TNBC).

Ann OncolMay 30, 2026Read summary
Clinical ResearchOncology (Medical)

Results of a Phase 1 Open-Label, Dose-Escalation Study of Gene Therapy With AAV2-hAQP1 for Grade 2 and 3 Radiation-Induced Late Xerostomia and Parotid Gland Hypofunction.

This Phase 1 open-label, multicenter study evaluated the safety and efficacy of AAV2-hAQP1 gene therapy in 24 patients with grade 2 and 3 radiation-induced late xerostomia.

Int J Radiat Oncol Biol PhysMay 29, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Efficacy and safety of durvalumab with or without tremelimumab in the treatment of metastatic non-small cell lung cancer: a meta-analysis of randomized controlled trials.

This meta-analysis evaluated the efficacy and safety of durvalumab with or without tremelimumab in 2726 patients with metastatic non-small cell lung cancer (NSCLC).

Proc (Bayl Univ Med Cent)May 29, 2026Read summary
Clinical ResearchOncology (Medical)

Lorlatinib versus crizotinib as first-line treatment for advanced ALK-positive non-small-cell lung cancer: 7-year update from the phase III CROWN study.

The phase III CROWN study evaluated lorlatinib versus crizotinib in treatment-naive patients with advanced ALK-positive non-small-cell lung cancer (NSCLC).

Ann OncolMay 29, 2026Read summary
Clinical ResearchOncology (Medical)

The Use of Ketamine for Depression in Cancer Patients: A Systematic Review of Efficacy, Safety, and Clinical Applications.

This systematic review evaluated the efficacy and safety of ketamine for treating depression in adult cancer patients. Analyzing 14 studies, it found that ketamine can provide rapid relief from depressive symptoms…

J Pain Palliat Care PharmacotherMay 29, 2026Read summary
Clinical ResearchUrologyOpen access

Micro- and nanoplastics in the human genitourinary system: oncological impact - a systematic review.

This systematic review evaluated the presence and impact of micro- and nanoplastics (MNPs) in human urinary and male reproductive tissues.

BJU IntMay 29, 2026Read summary
Clinical ResearchOncology (Medical)Open access

FDG-PET/CT Parameters for distinguishing high and low microsatellite instability in colorectal cancer: A systematic review and Meta-analysis.

This systematic review and meta-analysis evaluated the effectiveness of FDG-PET/CT parameters in distinguishing high microsatellite instability (MSI-H) from low microsatellite instability (MSI-L) in colorectal cancer…

Ann Nucl MedMay 29, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Maintenance treatment and survival in patients with newly diagnosed diffuse large B cell lymphoma in the immunochemotherapy era: a systematic review and network meta-analysis.

This systematic review and network meta-analysis compared maintenance strategies after initial treatment in previously untreated patients with diffuse large B-cell lymphoma (DLBCL), using randomized trials.

Clin Transl OncolMay 29, 2026Read summary
Case ReportNeurology

Cortex on Fire: Infarct Mimicking Ictal.

A 65-year-old woman with treated small cell lung cancer presenting with recurrent stroke-like symptoms and seizures underwent FDG PET/CT and MRI. Brain MRI revealed diffusion restriction.

Clin Nucl MedMay 28, 2026Read case
Clinical ResearchOncology (Medical)

Comparison of the EORTC QLQ-EN24, FACT-En, and FEnSI-23 for assessing quality of life in endometrial cancer: a systematic review.

This systematic review compares three patient-reported outcome measures for assessing quality of life in endometrial cancer: EORTC QLQ-EN24, FACT-En, and FEnSI-23.

Curr Opin Support Palliat CareMay 28, 2026Read summary
Case ReportGeneral SurgeryOpen access

Laparoscopic Minimally Invasive Approach for Left Paracaval Retroperitoneal Schwannoma.

A 55-year-old man presented with an incidentally found retroperitoneal mass, identified as a 4 cm schwannoma via endoscopic ultrasound-guided biopsy.

Ann Surg OncolMay 28, 2026Read case
Clinical ResearchOncology (Medical)

The Use of Corticosteroid Treatment Protocols in Compressive Epidural Spinal Metastases: Current Practice and the Need for Consensus.

This systematic review evaluated corticosteroid treatment protocols in patients with compressive epidural spinal metastases.

Spine (Phila Pa 1976)May 28, 2026Read summary
Clinical ResearchOncology (Medical)

Radiotherapy for newly diagnosed adult high grade gliomas in the Asia Pacific Region.

This systematic review examined radiotherapy protocols for newly diagnosed adult high grade gliomas (HGG) in the Asia Pacific region.

J Clin NeurosciMay 28, 2026Read summary
Case ReportOncology (Medical)Open access

Diffuse Large B-Cell Lymphoma Presenting as a Thigh Mass: A Case Report.

A 76-year-old female presented with swelling and pain in her right thigh. Imaging revealed a soft-tissue mass that raised concerns for sarcoma.

Perm JMay 28, 2026Read case
Case ReportUrology

Neoplasms in prune belly syndrome: A novel case of early-onset metastatic bladder carcinoma and systematic review of reported tumors.

A 33-year-old man with Prune Belly Syndrome (PBS) presented with metastatic muscle-invasive urothelial carcinoma. Despite advances in care for PBS, he developed this aggressive malignancy, which is noted to occur at…

J Pediatr UrolMay 27, 2026Read case
Clinical ResearchOncology (Medical)

Role of diffusion-weighted MRI in assessing Ewing sarcoma treatment response: Findings from a COG phase III trial.

This phase III multicenter trial evaluated the correlation between diffusion-weighted MRI measures and glucose metabolism in 21 patients with metastatic Ewing sarcoma.

Magn Reson ImagingMay 27, 2026Read summary
Clinical ResearchGeneral SurgeryOpen access

Microsurgical treatment of lower extremity lymphedema: An umbrella systematic review supporting the American Venous Forum and the American Vein and Lymphatic Society clinical practice guidelines on management of lymphedema.

This umbrella systematic review evaluated the effectiveness of lymphovenous anastomosis (LVA) and vascularized lymph node transfer (VLNT) for lower extremity lymphedema (LEL) by analyzing 26 systematic reviews and 14…

J Vasc Surg Venous Lymphat DisordMay 27, 2026Read summary
Case ReportOncology (Medical)

Uterine Myxoid Inflammatory Myofibroblastic Sarcoma (MIMS) Harboring Pathogenic KRAS Mutations and Expressing ER, PR, and CD10.

A 40-year-old woman presented with a uterine tumor characterized by a whorled architecture and myxoid stroma. Immunohistochemical analysis revealed positivity for CD10, estrogen receptor (ER), and progesterone receptor…

Int J Gynecol PatholMay 27, 2026Read case
Case ReportEndocrinology

Multimodal management of giant prolactinoma with extensive amyloid spherule deposition: a case report with review of the literature.

A 49-year-old man presented with headache and visual disturbances due to a giant prolactinoma, measuring 63 × 84 × 46 mm, with significant cavernous sinus invasion and marked hyperprolactinemia (30,969 ng/mL).

Endocr JMay 27, 2026Read case
Case ReportOncology (Medical)

Primary SMARCB1-deficient intestinal carcinoma: Clinicopathological and molecular characterization of three cases with analysis of published data.

This report details three cases of primary SMARCB1-deficient intestinal carcinoma (SdIC), a rare and aggressive cancer type.

Pathol Res PractMay 26, 2026Read case
Clinical ResearchOncology (Medical)

Title: Role of O6-methylguanine DNA methyltransferase status as predictive factor for alkylatin-based chemotherapy in advanced neuroendocrine tumors: State of the art.

This systematic review evaluated the predictive role of O6-Methylguanine DNA Methyltransferase (MGMT) status in advanced neuroendocrine tumors (NETs) treated with alkylating agents, including temozolomide (TMZ).

Crit Rev Oncol HematolMay 26, 2026Read summary

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