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1998 articles
September 202624
Does a Simple Touch Make a Difference? The Effect of Acupressure on Pain Scores in Infants Undergoing Cardiac Catheterization: A Randomized, Placebo-Controlled Trial.
This randomized, placebo-controlled trial evaluated acupressure in 60 infants aged 1–12 months with congenital heart disease undergoing cardiac catheterization.
Effectiveness of psychosocial counselling on treatment adherence among patients with a new tuberculosis diagnosis in primary care: a study protocol for a cluster-randomised controlled trial.
This study protocol outlines a cluster-randomised controlled trial aimed at evaluating the effectiveness of psychosocial counselling on treatment adherence among newly diagnosed tuberculosis patients in primary care…
Efficacy and safety of tegoprazan-amoxicillin dual therapy versus bismuth-containing quadruple therapy for first-line Helicobacter pylori eradication: a systematic review and meta-analysis of randomized controlled trials.
This systematic review and meta-analysis evaluated the efficacy and safety of 14-day tegoprazan-amoxicillin dual therapy versus bismuth-containing quadruple therapy (BQT) for first-line Helicobacter pylori eradication…
Imaging biomarkers for cardiometabolic risk stratification in metabolic dysfunction-associated steatotic liver disease: incremental value of coronary artery calcification, epicardial adipose tissue, controlled attenuation parameter, and liver stiffness measurement beyond clinical scores.
This systematic review analyzed 16 observational studies involving 34,713 adults with metabolic dysfunction-associated steatotic liver disease (MASLD) to evaluate the association between MASLD and imaging biomarkers of…
Effect of early regional anesthesia on postoperative cognitive function and the perioperative stress response in patients with hip fractures: a randomized controlled trial.
This randomized controlled trial investigated the effect of anterior iliopsoas muscle space block (AIMSB) timing on postoperative delirium (POD) in 79 elderly patients undergoing total hip arthroplasty for fractures.
Repetitive Transcranial Magnetic Stimulation Combined With Median Nerve Electrical Stimulation for Severe Traumatic Brain Injury.
This randomized controlled trial investigated the effects of repetitive transcranial magnetic stimulation (rTMS) combined with median nerve electrical stimulation (MNS) in 86 patients with severe traumatic brain injury…
Coffee consumption and head and neck cancer risk: a dose-response and site-specific meta-analysis.
This meta-analysis examined the relationship between coffee consumption and head and neck cancer (HNC) risk across 30 studies.
Age and antiplatelet de-escalation after myocardial infarction in the TALOS-AMI trial.
This secondary analysis of the TALOS-AMI randomized trial evaluated the effects of de-escalating from ticagrelor to clopidogrel on clinical outcomes in patients after myocardial infarction, stratified by age.
Lower HLA-B27 positivity and heterogeneous late-onset case proportions across axial spondyloarthritis cohorts: a systematic review and meta-analysis.
This systematic review and meta-analysis examined late-onset ankylosing spondylitis (AS) and axial spondyloarthritis (axSpA) in clinical cohorts, focusing on cases with onset at or after age 45.
Safety and efficacy of human gingiva-derived mesenchymal stem cells in patients with type 1 diabetes: a double-blind, randomized, placebo-controlled, phase 1 trial.
This phase 1 double-blind, randomized, placebo-controlled trial evaluated the safety and efficacy of human gingiva-derived mesenchymal stem cells (GMSCs) in 18 patients with type 1 diabetes mellitus (T1DM).
Continuous Intravenous Acyclovir as Outpatient Parenteral Antimicrobial Therapy for HSV and VZV Neurological Infections: A Case Series With Pharmacokinetic and Cost Evaluation, and Review of Literature.
This case series involved eight patients with neurological infections caused by HSV or VZV who transitioned to continuous intravenous acyclovir via an outpatient parenteral antimicrobial therapy (OPAT) program after…
Does baseline physical function modify the response to a physical activity intervention in adults with arthritis? A secondary analysis of a randomized trial.
This secondary analysis of a randomized controlled trial examined whether baseline physical function influenced the response to a telephone-delivered Walk With Ease (WWE-T) intervention in 267 adults with arthritis.
Severe upper limb soft tissue infection with compartment syndrome following a scratch injury: a case report.
A 58-year-old female teacher developed a severe soft tissue infection in her left arm following a minor scratch from a student.
When two rare diseases meet: atypical hemolytic uremic syndrome and alkaptonuria in two siblings.
Two brothers from a consanguineous family presented with recurrent episodes of atypical hemolytic uremic syndrome (aHUS) characterized by microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney injury.
A community-based participatory research and community health workers-led health education strategy for schistosomiasis control among schoolchildren in Pemba Island, Zanzibar: a cluster-randomized trial.
This cluster-randomized controlled trial evaluated a community-based participatory research (CBPR) approach led by community health workers for schistosomiasis control among schoolchildren in Pemba, Zanzibar.
8 weeks versus 12 weeks of sofosbuvir-velpatasvir for treatment-naive, non-cirrhotic, chronic hepatitis C (RESOLVE): a multicentre, open-label, non-inferiority, randomised controlled trial in India.
The RESOLVE multicentre, open-label, randomised non-inferiority trial compared 8 versus 12 weeks of daily sofosbuvir-velpatasvir in treatment-naive adults with chronic hepatitis C without cirrhosis at five publicly…
16S rRNA Datasets of Gut Microbiota in Stent-Based Diverting Technique and Ileostomy from A Prospective, Open-Label, Multicenter Randomized Controlled Trial.
This study presents a 16S rRNA amplicon dataset from a multicenter randomized controlled trial involving 80 patients undergoing either a stent-based diverting technique (SDT) or ileostomy after rectal cancer surgery.
Cardiovascular safety of orforglipron versus insulin glargine in adults with type 2 diabetes at increased cardiovascular risk (ACHIEVE-4): a phase 3, event-driven, randomised, open-label, non-inferiority, active comparator trial.
ACHIEVE-4 was a phase 3, event-driven, multicentre, randomised, open-label, active-comparator non-inferiority trial comparing once-daily oral orforglipron with titrated insulin glargine in adults with type 2 diabetes…
Clinical, economic, and quality-of-life outcomes of brexucabtagene autoleucel for the treatment of relapsed/refractory mantle cell lymphoma and B-cell acute lymphoblastic leukemia: A systematic literature review and meta-analysis.
This systematic literature review and meta-analysis evaluated the clinical, healthcare resource use, and quality-of-life outcomes of brexucabtagene autoleucel in adults with relapsed/refractory mantle cell lymphoma…
FAT1-associated membranous nephropathy after hematopoietic stem cell transplantation: a case report and review of the literature.
A 55-year-old man developed nephrotic syndrome 52 months post-allogeneic hematopoietic stem cell transplantation for acute lymphoblastic leukemia.
Effectiveness, Mediators and Moderators of Remote Live vs. Pre-Recorded Physical Exercise Training for Chronic Low Back Pain.
This randomized controlled trial evaluated the effectiveness of live interactive versus pre-recorded remote exercise training for chronic low back pain (CLBP) in 94 patients.
Metastasis of Invasive Ductal Carcinoma of the Breast to the Uterine Cervix 30 Years Post-Mastectomy: A Case Report.
A 69-year-old woman, 30 years post-mastectomy for invasive ductal carcinoma, presented with abnormal cervical cytology. Imaging revealed a 38-mm cervical mass, leading to a modified radical hysterectomy.
Reducing Peripheral Intravenous Catheter Use in Adult Acute Care: A Systematic Review.
This systematic review evaluated interventions aimed at reducing peripheral intravenous catheter (PIVC) use in adult acute care settings.
More than meets the eye: A meta-analysis of visual outcomes following clipping, coiling, and flow diversion for visually symptomatic paraclinoid aneurysms.
This PRISMA-compliant systematic review and random-effects meta-analysis compared visual outcomes after clipping, coiling, and flow diversion for paraclinoid aneurysms, drawing on 21 studies.
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