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1891 articles

April 202624

Case ReportOncology (Medical)

Clear cell carcinoma developed on hepatic endometriosis: a case report and review of the literature.

A patient with a history of deep endometriosis involving the colon underwent surgery, after which she developed hepatic clear cell carcinoma on an endometriosis lesion.

J Gynecol Obstet Hum ReprodApr 29, 2026Read case
Clinical ResearchOncology (Medical)

Textbook outcome in cancer surgery and its prognostic value: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the prognostic value of textbook outcomes in cancer surgery across 63 cohort studies involving 393,073 patients.

Eur J Cancer PrevApr 29, 2026Read summary
Clinical ResearchUrologyOpen access

Indirect Comparison of Neoadjuvant Treatment Strategies for Muscle-Invasive Bladder Cancer: ddMVAC and Perioperative Durvalumab-Gemcitabine-Cisplatin Versus Gemcitabine-Cisplatin: A Systematic Review and Network Meta-Analysis of Randomised Controlled Trials.

This systematic review and network meta-analysis evaluated the efficacy of neoadjuvant treatment strategies for muscle-invasive bladder cancer (MIBC) in cisplatin-eligible patients.

Int J CancerApr 28, 2026Read summary
Case ReportOncology (Medical)

68 Ga-Trivehexin PET/CT Revealing Concomitant Papillary Thyroid Carcinoma and Parathyroid Adenoma.

A patient diagnosed with papillary thyroid carcinoma underwent preoperative imaging using 68 Ga-Trivehexin PET/CT. The imaging revealed not only the thyroid malignancy but also a concomitant parathyroid adenoma.

Clin Nucl MedApr 28, 2026Read case
Clinical ResearchOncology (Medical)

Long-Term Impact of First-Line Amivantamab Plus Lazertinib Versus Osimertinib on Mechanisms of Acquired Resistance in MARIPOSA: A Brief Report.

The MARIPOSA trial evaluated the long-term effects of first-line amivantamab plus lazertinib compared to osimertinib in patients with EGFR-mutated advanced NSCLC.

J Thorac OncolApr 28, 2026Read summary
Clinical ResearchGeneral Surgery

Comparison of Functional Outcomes Between Robotic and Laparoscopic Surgery in Rectal Cancer Patients: Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated functional outcomes of robotic versus laparoscopic surgery in 6,121 rectal cancer patients.

J Invest SurgApr 27, 2026Read summary
Case ReportOncology (Medical)

SMARCA4-deficient undifferentiated tumor in the oral cavity: a rare case report and review of the literature.

A 66-year-old man presented with a rapidly enlarging mass in the left posterior maxillary mucosa, accompanied by bone destruction.

Oral Surg Oral Med Oral Pathol Oral RadiolApr 27, 2026Read case
Case ReportOncology (Medical)

Extremely Rare Prostate Metastasis From Rectal Carcinoma Detected on ⁶⁸Ga-FAPI PET/CT.

A 52-year-old man with a history of rectal adenocarcinoma presented with lower urinary tract symptoms and rising serum creatinine levels.

Clin Nucl MedApr 27, 2026Read case
Clinical ResearchOncology (Medical)

Does Lymph Node Dissection During Esophagectomy Impact the Long-Term Prognosis for Complete Responders After Neoadjuvant Therapy? A Meta-analysis.

This meta-analysis examined the impact of lymph node dissection (LND) on long-term survival in 2578 patients with pathologic complete response (pCR) after neoadjuvant therapy for esophageal cancer.

Ann Surg OncolApr 27, 2026Read summary
Clinical ResearchOncology (Medical)

Nutritional intervention rich in tryptophan enhances sleep duration and reduces wakefulness during breast cancer treatment.

This randomized controlled trial evaluated the impact of a tryptophan-rich dietary intervention on sleep in 50 women undergoing chemotherapy for breast cancer.

Nutr NeurosciApr 25, 2026Read summary
Case ReportOncology (Medical)

BioGlue-induced inflammatory reaction mimicking oncologic recurrence in head and neck surgery: a case report.

A patient underwent cervical lymph node dissection where BioGlue was applied, leading to a mass-forming inflammatory reaction that resembled recurrent malignancy on imaging studies.

Oral Surg Oral Med Oral Pathol Oral RadiolApr 23, 2026Read case
Clinical ResearchOncology (Medical)

Outcomes of Stage IVA Cervical Cancer Treated with Radiation Therapy: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated survival outcomes and treatment-related morbidity in 492 patients with stage IVA cervical cancer treated with definitive radiotherapy.

Int J Radiat Oncol Biol PhysApr 23, 2026Read summary
Clinical ResearchOncology (Medical)

Matching-Adjusted Indirect Comparison of Sotorasib Plus Panitumumab Versus Trifluridine/Tipiracil Plus Bevacizumab in Chemorefractory Metastatic Colorectal Cancer.

This study conducted a matching-adjusted indirect comparison to evaluate the efficacy of sotorasib plus panitumumab (soto960+pani) versus trifluridine/tipiracil plus bevacizumab (T/T+bev) in patients with…

Clin Colorectal CancerApr 23, 2026Read summary
Case ReportPathology (Anatomic & Clinical)

A Primary Dedifferentiated Melanoma, Masquerading as a Soft Tissue Sarcoma, Displaying BRAF p.V600E, CDKN2A, TP53 , and TERT Promoter Mutations.

A 55-year-old woman presented with a slowly growing mass in the right popliteal region, initially diagnosed as synovial sarcoma.

Int J Surg PatholApr 23, 2026Read case
Case ReportDermatologyOpen access

Cutaneous Acral Presentation of Indolent Mantle Cell Lymphoma With Prominent Nail Involvement and Atypical Immunophenotype.

A 56-year-old healthy male presented with a 5-year history of painful, edematous plaques and nail dystrophy on his bilateral toes.

J Cutan PatholApr 23, 2026Read case
Case ReportOncology (Medical)

Micropapillary Serous Borderline Tumor With Microinvasive Low-Grade Serous Carcinoma of the Tunica Vaginalis Harboring NRAS p.Q61R Mutation: Expanding the Molecular Spectrum of Paratesticular Müllerian-Type Tumors.

A patient presented with a micropapillary serous borderline tumor of the tunica vaginalis, which also exhibited microinvasive low-grade serous carcinoma. Histopathological examination confirmed Müllerian differentiation.

Int J Surg PatholApr 23, 2026Read case
Clinical ResearchRadiology (Diagnostic)

A systematic review of transformer-enhanced UNet architectures for 3D medical image segmentation: Trends, challenges, and the ATD-TᵣEE v framework.

This systematic review evaluates transformer-enhanced UNet architectures for 3D medical image segmentation, focusing on their application in tumor detection.

Comput Biol ChemApr 22, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Clinical Benefit and Safety of Combined Immunotherapy and Targeted Therapy in Prostate Cancer.

This systematic review and meta-analysis evaluated the efficacy and safety of combined immunotherapy and targeted therapy in prostate cancer, involving 5702 participants across 21 studies.

Int J CancerApr 22, 2026Read summary
Clinical ResearchOncology (Medical)

Deulorlatinib (TGRX-326) in ALK Gene Fusion Positive NSCLC After Failure of Second-Generation Inhibitors: A Single-Arm, Multicenter, Phase 2 Trial.

This single-arm, phase 2 trial evaluated deulorlatinib (TGRX-326) in 158 patients with ALK-positive NSCLC who had previously failed second-generation inhibitors.

J Thorac OncolApr 22, 2026Read summary
Clinical ResearchOncology (Medical)

Relevance of tumour-infiltrating lymphocytes in oral mucosal melanoma: a systematic review.

This systematic review evaluated the prognostic significance of tumour-infiltrating lymphocytes (TILs) in oral mucosal melanoma (OMM), analyzing data from two studies involving 102 patients.

Int J Oral Maxillofac SurgApr 22, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Electrochemotherapy in pediatrics: a systematic review.

This systematic review evaluated electrochemotherapy (ECT) in pediatric patients, analyzing 15 studies involving at least 127 children.

Eur RadiolApr 22, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Understanding the Effects of Cancer-Related Factors on the Association Between Physical Activity and Quality of Life in Breast Cancer Survivors.

This randomized controlled trial analyzed the relationship between physical activity (PA) and quality of life (QoL) in 341 breast cancer survivors post-treatment.

J Phys Act HealthApr 22, 2026Read summary
Case ReportHematologyOpen access

Aggressive multiple myeloma with lymph node involvement, loss of CD138, and adipophilin-positive cytoplasmic vacuolization: a case report.

An 83-year-old woman presented with painless cervical lymphadenopathy and widespread osteolytic lesions, leading to a diagnosis of multiple myeloma (MM).

Med Mol MorpholApr 22, 2026Read case
Case ReportDermatologyOpen access

Diffuse CD30-Positive Cutaneous Infiltrate in a Clinically Suspected Hidradenitis Suppurativa Lesion: Histopathologic and Diagnostic Challenges.

A 38-year-old male presented with a lesion in the left axilla, initially diagnosed as hidradenitis suppurativa (HS) and unresponsive to antibiotics.

J Cutan PatholApr 22, 2026Read case

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