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379 articles
August 202624
Pharmacokinetics, Elimination and Dialyzability of HRS-9231 in Patients with Varying Degrees of Renal Impairment.
This Phase I clinical trial evaluated the pharmacokinetics, elimination, and dialyzability of HRS-9231 in 40 patients with varying degrees of renal impairment, including those on hemodialysis.
Protein requirements and determinants of protein catabolic rate in critically ill patients with acute kidney injury: A post hoc analysis of the ENGINE randomized controlled trial.
This post hoc analysis of the ENGINE randomized controlled trial evaluated protein requirements in 78 critically ill patients with acute kidney injury (AKI).
Daratumumab in Antibody-Mediated Rejection After Kidney Transplantation: Mechanistic Rationale, Published Clinical Experience, and a Single-Center Case Series.
Two highly sensitized kidney transplant recipients presented with early acute antibody-mediated rejection (AMR) characterized by persistent donor-specific antibodies (DSAs) despite first-line therapies.
Urinary Extracellular Vesicles as a Source of Biomarkers for Kidney Allograft Rejection: A Systematic Review.
This systematic review assessed urinary extracellular vesicle (uEV) biomarkers for detecting kidney allograft rejection. Sixteen studies were included, using varied vesicle-isolation methods and proteomic…
Evidence-based guidelines for the diagnosis and management of adult-onset IgA vasculitis.
This systematic review presents evidence-based guidelines for the diagnosis and management of adult-onset IgA vasculitis (IgAV), a rare condition with a poorer prognosis compared to childhood-onset.
First Moroccan ABO-Incompatible Living Donor Kidney Transplantation: Successful Desensitization Without Intravenous Immunoglobulin.
A 23-year-old woman with end-stage kidney disease due to congenital uropathy received a kidney transplant from her mother, despite ABO incompatibility (donor B+, recipient O+).
Successful Heart and Renal Allograft Transplantation From Patients With Child-Pugh Class C Cirrhosis.
This report details a successful heart and renal transplantation from a brain-dead donor with Child-Pugh class C cirrhosis and hepatorenal syndrome.
Intravascular Large B-Cell Lymphoma After Kidney Transplantation: A Rare Form of Post-Transplant Lymphoproliferative Disorder.
A Japanese man in his 60s developed intravascular large B-cell lymphoma (IVLBCL) 4.5 years after kidney transplantation, presenting with general fatigue and loss of appetite.
Pediatric Postoperative Acute Kidney Injury After Noncardiac Surgery: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the incidence of postoperative acute kidney injury (AKI) in children undergoing noncardiac surgery, analyzing data from 27 studies with 21,908 patients.
Oleanolic Acid-Enriched Olive Oil Attenuates Kidney Function Decline in Patients With Type 2 Diabetes: Results From the OLTRAD Randomised Controlled Trial.
This prespecified, exploratory secondary analysis of the OLTRAD randomised controlled trial assessed kidney outcomes in 97 patients with type 2 diabetes assigned to oleanolic acid (OA)-enriched or control olive oil for…
Twelve-Year Follow-up of a Family With CKD Caused by an mtDNA Variant.
Five siblings with unaffected parents presented with hyperuricemia and chronic kidney disease; the proband died of end-stage kidney disease at age 16.
68 Ga-FAPI-04 PET/CT Findings in Primary Hyperoxaluria Type 1.
A patient with primary hyperoxaluria type 1 presented with systemic oxalate deposition leading to end-stage renal disease. 68 Ga-FAPI-04 PET/CT imaging revealed significant FAPI uptake in various bones and joints…
Kidney outcomes and safety of sodium-glucose cotransporter-2 inhibitor therapy in autosomal dominant polycystic kidney disease: systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the efficacy and safety of sodium-glucose cotransporter-2 (SGLT2) inhibitors in 451 patients with autosomal dominant polycystic kidney disease (ADPKD).
Cardiometabolic Renal Health Profile, Intensive Blood Pressure-Lowering Treatment and Cognitive Dysfunction: A Post Hoc Analysis of the SPRINT Trial.
This post hoc analysis of the randomised SPRINT trial examined whether baseline cardiometabolic renal health profiles modified cognitive outcomes with intensive blood pressure lowering.
FDG PET/CT in a Case of Urothelial Carcinoma Arising From a Functional Renal Allograft.
Nine years after renal transplantation, a patient with a functional renal allograft was found to have high-grade urothelial carcinoma arising within the graft, with lymph node metastases.
Targeted versus empiric approach for prevention of recurrent kidney stones: Insights on diet therapy from a randomized trial.
This randomized controlled trial compared empiric and selective dietary therapy for preventing recurrent kidney stones in adults.
Cellulitis-like cutaneous cryptococcosis revealing disseminated infection in a kidney transplant recipient: a case report and systematic review.
A kidney transplant recipient developed cellulitis-like cutaneous lesions shortly after transplantation, which were later identified as a disseminated Cryptococcus neoformans infection.
Enlarging Bilateral Perinephric Masses in Nephrotic Syndrome.
A 62-year-old man with biopsy-proven focal segmental glomerulosclerosis presented with nephrotic syndrome and enlarging bilateral perinephric masses.
Calciphylaxis in chronic kidney disease: a systematic review of pathomechanisms and risk factors for calcific uremic arteriolopathy.
This systematic review examined the pathomechanisms and risk factors associated with calcific uremic arteriolopathy (CUA) in patients with chronic kidney disease (CKD).
Methodological pitfalls in indirect treatment comparisons: insights from a recent systematic review and analysis for C3 glomerulopathy.
This systematic review evaluated the feasibility of indirect treatment comparisons (ITCs) for C3 glomerulopathy (C3G) by analyzing Phase III trials of iptacopan and pegcetacoplan.
Effect of semaglutide on kidney outcomes in the SELECT, FLOW, and SOUL trials: a prespecified pooled analysis.
This pooled analysis of participant-level data from the SELECT, FLOW, and SOUL trials evaluated the effects of semaglutide on kidney outcomes in individuals with type 2 diabetes and chronic kidney disease.
From static to dynamic SPECT/CT: A systematic review of clinical applications and perspectives.
This systematic review evaluates the clinical applications of dynamic SPECT/CT across various organ systems, particularly in cardiology and nephrology.
Effect of levothyroxine therapy on albuminuria and glomerular function in patients with type 2 diabetes and subclinical Hypothyroidism: a randomized controlled pilot trial.
This randomized controlled pilot trial evaluated the impact of levothyroxine therapy on renal outcomes in 60 adults with type 2 diabetes and subclinical hypothyroidism over 6 months.
Efficacy and safety of revascularization in patients with chronic limb-threatening ischemia by kidney function.
This randomized controlled trial analyzed the efficacy and safety of surgical versus endovascular revascularization in 1,704 patients with chronic limb-threatening ischemia (CLTI) stratified by kidney function.
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