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441 articles

August 202624

Clinical ResearchGeriatrics

Effects of NLP Chatbots on Loneliness, Depression, and Quality of Life Among Older Adults: A Systematic Review.

This systematic review evaluated the effectiveness of NLP-based chatbots in reducing loneliness and depression among older adults.

J Am Med Dir AssocAug 20, 2026Read summary
Clinical ResearchGeriatricsOpen access

Fasting plasma amino acid profiles after resistance exercise with or without nutritional supplementation in older adults: an exploratory analysis of secondary outcomes from a randomized controlled trial.

This randomized controlled trial investigated fasting plasma amino acid profiles in community-dwelling older adults undergoing a 12-week resistance exercise program, with or without protein and micronutrient…

J Nutr Health AgingAug 19, 2026Read summary
Clinical ResearchGeriatrics

Animal-Assisted Interventions Involving Live and Robotic Animals for Depression, Anxiety, Loneliness, and Cognitive Function in Older Adults: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated the effectiveness of animal-assisted interventions (AAIs) on depressive symptoms, anxiety, loneliness, and cognitive function in older adults.

J Am Med Dir AssocAug 18, 2026Read summary
Clinical ResearchGeriatrics

A Systematic Review of the Effectiveness of Delirium Recovery Interventions.

This systematic review evaluated nonpharmacologic delirium recovery interventions in adults with ongoing delirium. It assessed reporting completeness, intervention effectiveness, and recovery domains.

J Am Med Dir AssocAug 18, 2026Read summary
Clinical ResearchGeriatricsOpen access

Medication safety in older adults in India: an integrative PhD synthesis of direct evidence and contextual implementation evidence.

This systematic review synthesizes evidence on medication safety among older adults in India, highlighting issues like polypharmacy and inappropriate prescribing.

Glob Health ActionAug 17, 2026Read summary
Clinical ResearchGeriatrics

Effects of exercise on balance function in people with osteoporosis: A systematic review and meta-analysis of randomized controlled trials.

This systematic review and meta-analysis pooled randomized controlled trials of exercise and balance function in people with osteoporosis. Thirteen studies met the inclusion criteria.

Public HealthAug 17, 2026Read summary
Clinical ResearchGeriatrics

Exercise modalities for overall and domain-specific balance performance in older adults: A systematic review and Bayesian network meta-analysis.

This systematic review and Bayesian network meta-analysis evaluated the effects of various exercise modalities on balance performance in older adults aged 60 and above.

Ageing Res RevAug 14, 2026Read summary
Clinical ResearchGeriatrics

Effect of a PROtein-enriched MEDiterranean diet and EXercise (PROMED-EX) on nutritional status and cognitive performance in older adults at risk of undernutrition and cognitive decline: the PROMED-EX randomized controlled trial.

The PROMED-EX randomized controlled trial evaluated the effects of a protein-enriched Mediterranean diet with and without exercise on nutritional status and cognitive performance in 105 older adults at risk of…

Am J Clin NutrAug 14, 2026Read summary
Clinical ResearchGeriatrics

A self-selected vegan diet reduces skeletal muscle mass in healthy older adults: a randomized controlled trial.

This randomized controlled trial examined the effects of a self-selected vegan diet on skeletal muscle mass and protein synthesis in 72 healthy older adults aged 65 and above.

Am J Clin NutrAug 14, 2026Read summary
Clinical ResearchCardiology

Minimally invasive extracorporeal circulation protects against postoperative pulmonary endothelial injury in elderly cardiac surgery via suppressing the C5a-mtDNA-cGAS-STING axis: a mechanistic randomized controlled trial.

This randomized controlled trial investigated the effects of minimally invasive extracorporeal circulation (MiECC) on postoperative pulmonary complications in 94 elderly patients (≥70 years) undergoing cardiac surgery.

Int ImmunopharmacolAug 14, 2026Read summary
Clinical ResearchGeriatricsOpen access

Effects of a multidomain intervention on physical performance and sarcopenia in long-term care facility residents: The I-COUNT pilot randomized controlled trial.

The I-COUNT pilot study assessed a multidomain intervention's effects on physical performance and sarcopenia in residents aged ≥70 years in long-term care facilities.

J Nutr Health AgingAug 13, 2026Read summary
Clinical ResearchGeriatrics

Effectiveness of psychosocial and lifestyle interventions in promoting behaviour change and improving cognitive outcomes in older people with memory concerns: A systematic review.

This systematic review evaluated the effectiveness of psychosocial and lifestyle interventions on behavior change and cognitive outcomes in older adults with memory concerns.

Ageing Res RevAug 12, 2026Read summary
Clinical ResearchGeriatricsOpen access

Radial shockwave therapy versus short-wave diathermy for pain, neuromechanical, and functional outcomes in older adults with lumbar spondylosis: a randomized controlled trial.

This randomized controlled trial compared radial shockwave therapy (RSWT) and short-wave diathermy (SWD) in 30 older adults (≥60 years) with lumbar spondylosis.

Clin RheumatolAug 12, 2026Read summary
Clinical ResearchGeriatrics

Postintensive Care Frailty of Older Patients With Septic Shock: A Post Hoc Analysis of a Multicenter Randomized Controlled Trial.

This post hoc analysis of a multicenter randomized controlled trial examined frailty progression in older adults (≥65 years) recovering from septic shock.

Crit Care MedAug 12, 2026Read summary
Clinical ResearchNephrology

Cardiometabolic Renal Health Profile, Intensive Blood Pressure-Lowering Treatment and Cognitive Dysfunction: A Post Hoc Analysis of the SPRINT Trial.

This post hoc analysis of the randomised SPRINT trial examined whether baseline cardiometabolic renal health profiles modified cognitive outcomes with intensive blood pressure lowering.

Diabetes Obes MetabAug 12, 2026Read summary
Clinical ResearchGeriatrics

A Nurse-Led Metamemory-Based Intervention to Improve Medication Adherence in Older Adults With H-Type Hypertension: A Randomized Controlled Trial.

This 12-week randomized controlled trial evaluated a nurse-led metamemory-based intervention in older adults with H-type hypertension.

J Cardiovasc NursAug 12, 2026Read summary
Case ReportInfectious DiseasesOpen access

Tuberculous Arthritis Diagnosed by Metagenomic Sequencing after Negative Microbiology Studies and a 4-Year Delay.

A 70-year-old man receiving treatment for lung cancer had chronic left knee pain and recurrent swelling. Two arthroscopic procedures were performed, but repeated standard tuberculosis tests were negative.

Am J Trop Med HygAug 11, 2026Read case
Clinical ResearchCardiologyOpen access

Effects of exercise snacks on cardiorespiratory fitness, body composition, and blood lipids in adults across different age groups: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the impact of exercise snacks on cardiorespiratory fitness, body composition, and blood lipids in adults across various age groups.

J Nutr Health AgingAug 10, 2026Read summary
Clinical ResearchEndocrinologyOpen access

Cost Effectiveness of Teriparatide for Postmenopausal Osteoporosis: A Systematic Review.

This systematic review evaluated the cost effectiveness of teriparatide for postmenopausal osteoporosis, analyzing 22 economic evaluations.

Clin Drug InvestigAug 8, 2026Read summary
Case ReportDermatology

Aminolevulinic acid photodynamic therapy for extensive genital extramammary Paget disease in older patients: A retrospective clinical case series.

Three older patients with extensive extramammary Paget disease (EMPD) affecting sensitive genital areas were treated with aminolevulinic acid photodynamic therapy (ALA-PDT) after declining surgery.

Photodiagnosis Photodyn TherAug 8, 2026Read case
Clinical ResearchGeriatrics

Effects of exercise and nutritional interventions on muscle-specific strength in older adults: A systematic review and meta-analysis.

This systematic review and meta-analysis examined randomized controlled trials of interventions targeting muscle-specific strength—strength normalized by muscle mass—in adults aged 60 years or older.

Ageing Res RevAug 8, 2026Read summary
Clinical ResearchInternal Medicine (General)Open access

Rethinking Muscle Wasting in Critical Illness: A Systematic Review and Meta-Analysis of Myofiber Size and Protein Turnover.

This systematic review and meta-analysis examined skeletal muscle dysfunction in adults with critical illness, analyzing myofiber size and protein turnover.

Crit Care MedAug 7, 2026Read summary
Case ReportGastroenterologyOpen access

Acute-on-chronic liver failure following pneumonia in an elderly woman with metabolic dysfunction-associated steatotic liver cirrhosis.

A woman in her 80s with cirrhosis associated with metabolic dysfunction-associated steatotic liver disease developed prolonged acute-on-chronic liver failure (ACLF) triggered by pneumonia.

Clin J GastroenterolAug 7, 2026Read case
Clinical ResearchPsychiatryOpen access

Psychological adversities and epigenetic ageing in midlife and older age: A systematic review and meta-analysis.

This systematic review and meta-analysis examined associations between psychological adversities and epigenetic age acceleration (EAA) from midlife onward.

J Prev Alzheimers DisAug 7, 2026Read summary

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