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785 articles
September 202624
Identification of a new, likely pathogenic, heterozygous ABCB4 variant causing low phospholipid-associated cholelithiasis.
A late adolescent boy presented with recurrent biliary symptoms after cholecystectomy, alongside elevated cholestatic liver enzymes and a family history of hepatobiliary disease.
Long-term outcomes in recurrent diverticulitis: a systematic review of treatment strategies and recurrence rates.
This systematic review evaluated long-term outcomes of treatment strategies for recurrent diverticulitis in 446 patients. It found recurrence rates ranging from 5.6% to 21.1% over follow-up periods of 17 to 190 months.
Primary Hepatic Lymphoma with Hepatocellular Carcinoma: A Case Report.
A patient with hepatocellular carcinoma (HCC) presented with atypical imaging findings that led to the discovery of primary hepatic lymphoma (PHL).
Endoscopic ultrasound-guided left gastric vein embolization for esophageal and gastric varices in liver cirrhosis: A case report.
A 47-year-old man with decompensated cirrhosis presented with hematemesis and melena. Imaging revealed portal hypertension and gastroesophageal varices.
Cost-effectiveness analysis of omeprazole for preventing esophageal stricture in patients with Zargar grade 2b and 3a corrosive esophageal injuries: A trial-based economic evaluation.
This randomized controlled trial evaluated the cost-effectiveness of omeprazole combined with standard treatment versus standard treatment alone in adults with Zargar grade 2b and 3a corrosive esophageal injuries.
Long-term outcome of percutaneous transhepatic venous embolization for ectopic peristomal variceal bleeding: A case report.
A patient with an ileal neobladder experienced recurrent hematuria due to ectopic peristomal varices linked to portal hypertension.
Acute bowel ischemia in the absence of radiological findings: A case for endoscopy.
A 73-year-old man presented in septic shock with elevated inflammatory markers and inconclusive clinical and radiological findings for bowel ischemia. Endoscopy was performed, revealing transmural bowel ischemia.
Randomized controlled trial comparing 7-day fexuprazan-based and 14-day rabeprazole-based triple therapies for Helicobacter pylori eradication.
This randomized controlled trial evaluated the efficacy and safety of a 7-day fexuprazan-based triple therapy versus a 14-day rabeprazole-based regimen for Helicobacter pylori eradication in Korean patients.
Multitarget Pharmacological Mechanisms and Safety Profiles of Six Ethnobotanically Prioritized Indonesian Medicinal Plants for Cardiometabolic Disorders: A Systematic Review.
This systematic review evaluated the pharmacological effects and safety of six Indonesian medicinal plants for cardiometabolic disorders.
Normothermic machine perfusion versus static cold storage for liver transplantation: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the effectiveness of normothermic machine perfusion (NMP) versus static cold storage (SCS) in liver transplantation, involving 630 recipients across five studies.
Clinical and genetic analysis of a family with 16p11.2 microduplication syndrome and variable multisystem manifestations.
A multigenerational family was studied for 16p11.2 microduplication syndrome, with the proband presenting symptoms including limb muscle pain, exercise intolerance, and chronic gastrointestinal issues.
Oncological impact of adjuvant chemotherapy after rectal cancer excision in the era of FOLFIRINOX-based TNT: A pooled post-hoc analysis of GRECCAR4-PRODIGE23.
This multicenter randomized controlled trial analyzed the impact of adjuvant chemotherapy (AC) on oncological outcomes in patients with locally advanced rectal cancer (LARC) following total neoadjuvant therapy (TNT) or…
Redo Heller myotomy vs. POEM after failed Heller myotomy: a systematic review and meta-analysis.
This systematic review and meta-analysis compared redo Heller myotomy and peroral endoscopic myotomy (POEM) in 631 patients with recurrent symptoms after laparoscopic Heller myotomy.
Long-term outcomes of top-down therapy versus a conventional step-up strategy in adults newly diagnosed with Crohn's disease: 5-year follow-up of the PROFILE trial.
This multicentre, open-label randomised trial follow-up compared early top-down infliximab plus an immunomodulator with protocolised step-up treatment in adults aged 16–80 years newly diagnosed with Crohn’s disease.
Clinical Trial: Randomised Placebo-Controlled Trial of Methylcellulose and Psyllium Gels on Inulin-Induced Colonic Gas.
This three-way randomised crossover trial compared methylcellulose, psyllium and maltodextrin placebo, each given with inulin, in 22 healthy volunteers.
Optimization strategies for care‑giving behaviors of family caregivers for patients with enterostomy: An evidence summary.
This systematic review summarizes evidence on optimizing caregiving behaviors for family caregivers of patients with enterostomy.
Genetic basis of pancreatic steatosis: a systematic review of comparison between African and non-African populations.
This systematic review examined genetic factors associated with pancreatic steatosis in African versus non-African populations, analyzing data from over 120,000 participants.
Comparing long-term weight loss and complications in endoscopic sleeve gastroplasty and laparoscopic sleeve gastrectomy: a systematic review and meta-analysis.
This systematic review and meta-analysis compared long-term outcomes of endoscopic sleeve gastroplasty (ESG) and laparoscopic sleeve gastrectomy (LSG) in 7442 patients.
Prevalence of fatty liver and diabetes mellitus in patients with fatty pancreas disorder (FPD): A meta-analysis and systematic review.
This systematic review and meta-analysis examined fatty liver and diabetes mellitus (DM) in patients with fatty pancreas disorder (FPD), pooling data from 19 studies involving 6,834 patients.
Diabetes-specific nutritional formulas for tube feeding in patients with hyperglycemia: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the effects of diabetes-specific nutritional formulas (DSNF) in tube feeding on glycemic control in patients with hyperglycemia.
Comorbidities in clinical cohorts of patients with idiopathic pulmonary fibrosis: a systematic review and meta-analysis.
This systematic review and meta-analysis examined the prevalence and impact of comorbidities in 606,398 patients with idiopathic pulmonary fibrosis (IPF).
Beyond the Liver: Metabolic Dysfunction Associated Steatotic Liver Disease (MASLD) Associated 35% Higher Risk of Clinically Diagnosed Heart Failure With Preserved Ejection Fraction (HFpEF).
This systematic review and meta-analysis examined the association between metabolic dysfunction-associated steatotic liver disease (MASLD) and heart failure with preserved ejection fraction (HFpEF) in a population of…
Understanding the gut microbiota to shape the future of intestinal failure care: a systematic review of the evidence.
Intestinal failure (IF) patients suffer a loss of intestinal mass or function and alterations in gut microbiota (GM) composition and function.
Comparative Efficacy of Different AI Systems for Polyp Detection by Size During Colonoscopy: Systematic Review and Network Meta-Analysis.
This systematic review and network meta-analysis evaluated the efficacy of AI-assisted colonoscopy compared to standard colonoscopy for polyp detection by size in adults.
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