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379 articles
July 202624
Diagnosing Mendelian Kidney Disease: Hidden Niches in the (Kidney) Genome.
A family with a history of autosomal dominant kidney disease presented with renal failure in middle adulthood. Genetic analysis revealed the index patient had both autosomal dominant polycystic kidney disease (ADPKD)…
Circulating KIM-1 and survival outcomes in renal cell carcinoma: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the prognostic significance of circulating kidney injury molecule-1 (KIM-1) in renal cell carcinoma (RCC) across 2,415 patients from 7 studies.
Regional Citrate Anticoagulation Versus No Anticoagulation During Continuous Renal Replacement Therapy in Critically Ill Patients at High Risk of Bleeding: A Meta-analysis of Randomized Controlled Trials.
This meta-analysis evaluated regional citrate anticoagulation (RCA) versus no anticoagulation (NA) during continuous renal replacement therapy (CRRT) in critically ill patients at high bleeding risk.
Chronic hepatitis E and Medicopsis romeroi coinfection in a Canadian renal transplant recipient: a case report.
A Canadian renal transplant recipient presented with chronic hepatitis E virus infection and subcutaneous phaeohyphomycosis caused by Medicopsis romeroi.
Efficacy and Tolerability of Overnight Bladder Drainage Post Posterior Urethral Valve Ablation on Upper and Lower Urinary Tracts: A Randomized Controlled Trial.
This randomized controlled trial assessed overnight bladder drainage (OBD) in boys with persistent hydronephrosis and unfavorable bladder dynamics after endoscopic posterior urethral valve ablation.
Multifocal Hepatic Epstein-Barr Virus-Associated Smooth Muscle Tumor Mimicking Posttransplant Lymphoproliferative Disorder in a Renal Allograft Recipient.
A 19-year-old renal transplant recipient presented with abdominal symptoms suggestive of posttransplant lymphoproliferative disorder (PTLD). Imaging with 18F-FDG PET/CT revealed multiple hypermetabolic liver lesions.
Variability in magnitude and direction of discordance between continuous glucose monitoring (CGM) metrics and traditional biomarkers in patients with diabetes and end-stage kidney disease (ESKD): A case series.
Four patients with diabetes and end-stage kidney disease exhibited significant discordance between glycated hemoglobin A1c (HbA1c) and continuous glucose monitoring (CGM) metrics.
Home blood pressure telemonitoring reveals race-specific patterns of target organ damage.
This multicenter randomized controlled trial examined racial differences in target organ damage (TOD) among high-risk Black and White patients aged 55-75 with home blood pressure monitoring.
Time in Target Range for Hemoglobin A 1c and Systolic Blood Pressure: Association With Adverse Kidney Events.
This observational cohort study analyzed data from 6,542 participants in the ACCORD trial to evaluate the association of time in target range (TTR) for hemoglobin A1c (HbA1c) and systolic blood pressure (SBP) with…
Effects on mortality of different blood purification techniques in sepsis patients: an umbrella review of systematic reviews and meta-analyses.
This umbrella review analyzed 42 systematic reviews and meta-analyses to assess the impact of various extracorporeal blood purification techniques on mortality in sepsis patients.
Design, rationale, and baseline patient characteristics for the Sickle Cell Disease and CardiovAscular Risk-Red cell Exchange (SCD-CARRE) trial.
The Sickle Cell Disease and CardiovAscular Risk-Red cell Exchange (SCD-CARRE) trial is a randomized controlled trial assessing the impact of automated red blood cell exchange (RBCX) on health outcomes in 173 adults with…
Delayed intestinal perforation caused by overheated peritoneal dialysate: A disease prone to missed diagnosis and misdiagnosis.
A 62-year-old woman on continuous ambulatory peritoneal dialysis presented with abdominal pain after receiving dialysate heated to 49 °C due to a malfunction.
Novel biomarkers for acute kidney injury in high-risk pediatric populations: a systematic review.
This systematic review evaluated the diagnostic accuracy of novel biomarkers for early detection of acute kidney injury (AKI) in high-risk pediatric populations.
Intensified multifactorial intervention leads to long-term benefit on kidney outcomes in advanced diabetic kidney disease: A 10-year follow-up of the DNETT-Japan trial.
This randomized controlled trial evaluated the long-term effects of an intensive multifactorial treatment on kidney outcomes in 164 patients with advanced diabetic kidney disease over a 10-year period.
An Interactive Virtual Nephrologist to Engage Patients With Advanced CKD About Transplantation.
This single-arm, open-label trial evaluated the impact of a virtual nephrologist on patient engagement regarding kidney transplantation (KT) among adults with advanced chronic kidney disease.
Metagenomic next-generation sequencing identifies Ureaplasma parvum in culture-negative peritoneal dialysis-associated peritonitis complicated by COVID-19: a case report.
A 43-year-old woman with stage 5 chronic kidney disease on peritoneal dialysis presented with abdominal pain, diarrhea, fever, and cloudy effluent. Initial empirical treatment was ineffective, and cultures were negative.
Localized renal artery vasculopathy: avoiding misdiagnosis between inflammatory arteritis and isolated renal artery dissection.
Two cases of unilateral renal artery pathology were initially misdiagnosed as vasculitis. The first case involved a 47-year-old man with acute flank pain, where imaging revealed perivascular tissue and a pseudoaneurysm…
Renal Impairment Does Not Affect Pharmacokinetics, Safety or Tolerability of Zenagamtide.
This Phase I clinical trial evaluated the pharmacokinetics, safety, and tolerability of zenagamtide in adults with varying degrees of renal impairment compared to those with normal renal function.
Lactiplantibacillus plantarum WJL ameliorates chronic kidney disease by inhibiting fibroblast growth factor 21 adaptive stress response via low protein diet.
This randomized controlled trial investigated the effects of Lactiplantibacillus plantarum WJL supplementation in nondiabetic chronic kidney disease (CKD) patients on a low-protein diet (LPD).
Sodium zirconium cyclosilicate compared with potassium restriction for hyperkalemia management in type 2 diabetes: The SILVERSTAR trial.
The SILVERSTAR trial evaluated the noninferiority of sodium zirconium cyclosilicate versus a potassium-restricted diet for managing hyperkalemia in individuals with type 2 diabetes.
Early-onset lipoprotein glomerulopathy in a 23-month-old boy with homozygous APOE Kyoto variant.
A 23-month-old boy presented with nephrotic syndrome and severe anaemia. A family history of kidney disease, parental consanguinity and enlarged echogenic kidneys on ultrasound prompted early renal biopsy, which showed…
An unusual presentation of scrub typhus as tetany: A case report.
A patient with scrub typhus presented with symptomatic hypocalcaemia and hypophosphataemia, likely due to renal tubular electrolyte loss.
Renal AA amyloidosis associated with a TRAPS-like autoinflammatory phenotype and TNFRSF1A R92Q variant in adulthood.
A 48-year-old male with a history of vitiligo presented with nephrotic syndrome, leading to a diagnosis of AA amyloidosis via renal biopsy.
Extended Double Plasma Molecular Adsorption Sessions and Bilirubin Clearance: A Case Report.
A 51-year-old male with hyperbilirubinemia underwent two extended sessions of double plasma molecular adsorption treatment, each lasting over 6 hours and utilizing more than 10 L of plasma.
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