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1064 articles

September 202624

Clinical ResearchPsychiatry

Psychosocial interventions for posttraumatic stress disorder in low- and middle-income countries: a Bayesian meta-analysis.

This meta-analysis evaluated the effectiveness of psychosocial interventions for adults with PTSD in low- and middle-income countries (LMICs). It included 55 randomized controlled trials with 5,041 participants.

Psychol MedSep 17, 2026Read summary
Clinical ResearchPsychiatry

Bilateral Transcranial Direct-Current Stimulation Over the Dorsolateral Prefrontal Cortex Significantly Reduces Relief Craving During Alcohol Withdrawal: A Randomized Sham-Controlled Trial Among Inpatients With Alcohol Dependence Syndrome in Northern India.

This randomized controlled trial investigated the effects of bilateral transcranial direct-current stimulation (tDCS) on relief craving in 48 male inpatients with alcohol dependence syndrome during withdrawal.

Prim Care Companion CNS DisordSep 17, 2026Read summary
Clinical ResearchPsychiatry

Psychiatric and medical multimorbidity in anorexia nervosa, bulimia nervosa, and binge-eating disorder: An umbrella review of 61 meta-analyses and 213 meta-analytic associations.

This umbrella review synthesized meta-analyses of observational studies on psychiatric and medical multimorbidity involving anorexia nervosa (AN), bulimia nervosa (BN), and binge-eating disorder (BED).

J Psychosom ResSep 17, 2026Read summary
Clinical ResearchNeurology

Pre-operative neural substrates of deep brain stimulation outcomes: A systematic review and cross-disorder network synthesis.

This systematic review and cross-disorder network synthesis examined whether pre-operative neuroimaging features are associated with deep brain stimulation (DBS) outcomes.

Neurosci Biobehav RevSep 17, 2026Read summary
Clinical ResearchPsychiatry

Medically Unexplained Symptoms: A Systematic Umbrella Review of Current Terminology and Reported Rationales.

This systematic umbrella review examined the terminology surrounding Medically Unexplained Symptoms (MUS) across 422 reviews. It identified 111 distinct terms, with 'functional' being the most common (n=233).

Clin J PainSep 16, 2026Read summary
Clinical ResearchEndocrinologyOpen access

Insights from changes in NDEV biomarkers of metabolism: effects of PPARγ and GLP1 receptor agonists on brain metabolism.

This randomized controlled trial examined the effects of pioglitazone (PPARγ agonist) and liraglutide (GLP1 receptor agonist) on central nervous system insulin signaling in participants with unremitted depression and…

J Clin Endocrinol MetabSep 16, 2026Read summary
Clinical ResearchPediatrics

Drawing and visual art interventions for anxiety in children aged 5-12: a systematic review and meta-analysis of randomised controlled trials.

This systematic review and meta-analysis evaluated the impact of drawing and visual art interventions on anxiety in children aged 5-12 years.

BMJ Paediatr OpenSep 16, 2026Read summary
Clinical ResearchGeriatrics

Prediction Models for In-Hospital Delirium Using Routinely Collected Electronic Health Record Data: Systematic Review.

This systematic review evaluated prediction models for in-hospital delirium using electronic health record data, analyzing 29 studies.

JMIR Med InformSep 16, 2026Read summary
Case ReportPsychiatry

Problematic Reliance on Generative AI in an Anxious Young Adult: Case Report.

A woman in her mid-20s with generalized anxiety disorder and major depressive disorder developed a functional dependence on generative AI tools, particularly ChatGPT, for cognitive and interpersonal tasks.

JMIR Form ResSep 16, 2026Read case
Clinical ResearchPsychiatry

Virtual Reality-Assisted Therapy Compared to Cognitive Behavioral Therapy for Patients With Treatment-Resistant Schizophrenia: Assessor-Blind Randomized Controlled Trial.

This assessor-blind randomized controlled trial compared virtual reality-assisted therapy (VRT) to cognitive behavioral therapy (CBT) in 136 adults with treatment-resistant schizophrenia and persistent auditory verbal…

JMIR Ment HealthSep 16, 2026Read summary
Clinical ResearchCardiology

Endotype-informed therapy and effects on illness perception and psychological health in patients with chest pain and no obstructive coronary artery disease.

The CorCMR trial, a multicenter randomized controlled trial, evaluated the impact of non-invasive stress perfusion cardiovascular magnetic resonance (CMR) on illness perception and psychological health in 250 patients…

Eur Heart J Qual Care Clin OutcomesSep 16, 2026Read summary
Clinical ResearchPsychiatry

Changes in dyadic emotional flexibility and expressivity during parent-child interactions following successful treatment of child anxiety.

This randomized controlled trial examined changes in dyadic emotional flexibility and expressivity during parent-child interactions following treatment for child anxiety in 116 children.

Dev PsychopatholSep 16, 2026Read summary
Clinical ResearchPsychiatry

Sleep quality and quality of life in people with non-affective psychosis: A systematic review of relationships across phases and age groups.

This PRISMA-guided systematic review examined associations between sleep quality and quality of life (QoL) in people with non-affective psychosis across illness phases and age groups.

Schizophr ResSep 16, 2026Read summary
Clinical ResearchPsychiatry

Psychological interventions for harmful gambling: Systematic review and network meta-analysis.

This systematic review and network meta-analysis compared psychological interventions for harmful gambling across 52 randomized controlled trials involving 9013 participants and 14 intervention classes.

J Behav AddictSep 16, 2026Read summary
Clinical ResearchNeurology

Safety and tolerability of temporal interference stimulation in humans: A systematic review and meta-analysis of an emerging deep neuromodulation technology.

This systematic review and meta-analysis assessed safety and tolerability of temporal interference stimulation (TIS) in human studies.

Neurosci Biobehav RevSep 16, 2026Read summary
Clinical ResearchPsychiatry

Early-stage trajectories of social-occupational functioning and long-term functional outcome prediction in early psychosis: A 12-year follow-up of the randomized controlled trial on extended early intervention.

This randomized controlled trial followed 148 participants with early psychosis over 12 years to examine early social-occupational functioning trajectories.

Psychol MedSep 15, 2026Read summary
Clinical ResearchNeurologyOpen access

Non-coding RNAs and Mitochondrial Dysfunction in Alzheimer's Disease: A Systematic Review.

This systematic review examined the role of non-coding RNAs (ncRNAs) in mitochondrial dysfunction associated with Alzheimer's disease (AD).

Mol NeurobiolSep 15, 2026Read summary
Clinical ResearchNeurologyOpen access

Deep brain stimulation for Tourette syndrome: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the efficacy of deep brain stimulation (DBS) for refractory Tourette syndrome (TS) across various brain targets.

Neurosurg RevSep 15, 2026Read summary
Clinical ResearchPsychiatry

Is appearance-related social comparison a causal mechanism underlying appearance-related psychopathology among young adult women? An experimental test.

This randomized controlled trial examined the impact of appearance-related social comparison (ARSC) fading on young adult women with high appearance concerns.

Behav Res TherSep 15, 2026Read summary
Clinical ResearchPsychiatry

Ketamine attenuates habenula activity in response to aversive outcomes during Pavlovian learning.

In a randomized, placebo-controlled translational study, 70 healthy adults received ketamine (0.5 mg/kg) or placebo (NaCl 0.9%) and completed an aversive Pavlovian conditioning task during 7-tesla functional…

Curr BiolSep 15, 2026Read summary
Clinical ResearchPsychiatry

Five-year outcomes in a randomised controlled trial of prolonged exposure therapy and supportive counselling for post-traumatic stress disorder in adolescents: a task-shifted intervention.

This randomized controlled trial evaluated the long-term effectiveness of prolonged exposure therapy (PE-A) and supportive counselling (SC) for adolescents with PTSD, with 63 participants followed for 60 months.

Eur J PsychotraumatolSep 14, 2026Read summary
Clinical ResearchObstetrics & GynecologyOpen access

Isolated physical activity programs during pregnancy and postpartum: Meta-analysis of randomized trials with usual-care controls on depressive and anxiety symptoms.

This meta-analysis evaluated the effects of isolated physical activity interventions on depressive and anxiety symptoms in pregnant and postpartum women. Seventeen randomized controlled trials were included.

Arch Womens Ment HealthSep 14, 2026Read summary
Clinical ResearchNeurology

Risk of neurodevelopmental disorders associated with paternal use of valproate during spermatogenesis: a living meta-analysis-version 1.

This living meta-analysis evaluated the association between paternal use of valproate during spermatogenesis and the risk of neurodevelopmental disorders (NDDs) in offspring, compared to lamotrigine or levetiracetam.

J Neurol Neurosurg PsychiatrySep 14, 2026Read summary
Clinical ResearchPsychiatry

Lumateperone as Adjunctive Therapy in Patients With Major Depressive Disorder and Anxious Distress: Post Hoc Analysis of a Phase 3, Randomized, Double-Blind Trial.

This post hoc analysis of a phase 3 randomized controlled trial evaluated the efficacy of adjunctive lumateperone 42 mg in patients aged 18-65 with major depressive disorder (MDD) and anxious distress.

J Clin PsychiatrySep 14, 2026Read summary

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