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1998 articles
October 202624
LigaSure versus conventional excisional haemorrhoidectomy: A systematic review and meta-analysis with trial sequential analysis of randomised controlled trials.
This systematic review and meta-analysis evaluated 43 randomized controlled trials involving 3,277 participants to compare LigaSure with conventional excisional haemorrhoidectomy.
A hypertensive response to irrigation: endoscopic repair of a ventral spinal CSF leak.
A 36-year-old woman with recurrent spontaneous intracranial hypotension due to a ventral T11-12 CSF leak underwent endoscopic repair.
Reporting Gaps in mHealth Intervention Studies for Adults With Diabetes: Systematic Review.
This systematic review evaluated the reporting completeness of 144 randomized controlled trials (RCTs) on mHealth interventions for adults with diabetes using the mERA checklist.
Development and usability testing of a Spanish version of a mobile app-based adaptive coping skills intervention for critical illness survivors: Blueprint en español.
This multicenter clinical trial focused on adapting the Blueprint mobile app-based coping skills intervention for critical illness survivors to Spanish.
Effects of high-dose supplemental oxygen therapy on pulmonary haemodynamics at 3250 m in high-altitude residents at risk for pulmonary hypertension.
This open-label, non-randomised trial investigated the effects of high-dose supplemental oxygen therapy (SOT) on pulmonary haemodynamics in Kyrgyz highlanders at 3250 m with elevated systolic pulmonary artery pressure…
A Systematic Review and Meta-Analysis of the Prevention and Management of Pediatric Urinary Tract Infection and Suspected Urinary Tract Infection: Technical Report.
This systematic review and meta-analysis evaluated management strategies for pediatric urinary tract infections (UTIs) in children without known anatomic anomalies, including antibiotic duration and route, and the use…
Persistent influenza A RNA detection in a fatal pediatric case of influenza-associated encephalopathy.
A 9-year-old boy developed fulminant influenza-associated encephalopathy, a life-threatening complication of influenza. Despite life-sustaining support, intensive immunomodulatory treatment, and antiviral therapy…
Resistant Hypertension Secondary to Renal Arteriovenous Malformation: A Case of Cure After Nephrectomy.
A 33-year-old woman with longstanding uncontrolled hypertension requiring five antihypertensive agents was evaluated for refractory blood pressure control.
Toxin-induced coagulopathy following a MacMahon viper bite.
A patient presented with a MacMahon viper bite, experiencing significant local envenomation, hypotension, and syncope. Laboratory tests showed rapid thrombocytopenia and impaired haemostatic function.
Toripalimab consolidation after chemoradiotherapy in limited-stage small cell lung cancer: a phase II, randomized controlled study (GASTO-1052A).
This phase II randomized controlled trial evaluated the efficacy and safety of toripalimab consolidation after chemoradiotherapy in patients with limited-stage small cell lung cancer (LS-SCLC).
Buruli Ulcer Acquired From Ringtail Possum Rescue.
A patient presented with a Buruli ulcer, which was likely acquired from a scratch by a ringtail possum during a rescue attempt. This case highlights a newly recognized transmission route for Buruli ulcer.
Retroperitoneal urinoma presenting as a posterior knee sinus following emphysematous pyelitis.
A woman in her late 40s presented with abdominal sepsis due to emphysematous pyelitis and a retroperitoneal urinoma. Despite initial treatment, she developed persistent thigh pain and a posterior knee sinus.
Enhanced recovery after colorectal surgery in patients with inflammatory bowel disease to reduce hospital length of stay: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the impact of enhanced recovery after surgery (ERAS) protocols on adult patients with inflammatory bowel disease (IBD).
Pharmacokinetics, Immunogenicity, and Safety of a Modified YTE Antibody in Healthy Adults.
This Phase I randomized controlled trial evaluated the pharmacokinetics, immunogenicity, and safety of REGN17092, a modified YTE antibody targeting SARS-CoV-2, in 40 healthy adults.
Carbon nanoparticle-Fe (II) complex for ferroptosis therapy in refractory solid tumors: a phase I trial.
This phase I trial evaluated the safety and preliminary efficacy of a carbon nanoparticle-Fe (II) complex (CNSI-Fe) in 19 patients with refractory solid tumors.
Presentation and management of tislelizumab induced toxic optic neuropathy.
A woman with metastatic lung adenocarcinoma developed painless, progressive bilateral visual blurring after receiving second-line treatment with gemcitabine, carboplatin, and tislelizumab.
Guillain-Barré syndrome temporally associated with respiratory syncytial virus vaccination.
An older woman experienced acute progressive limb weakness, pain, and paraesthesia two weeks post-respiratory syncytial virus vaccination.
Chlamydia psittaci Meningitis, Chile, 2023.
A 50-year-old farm worker in Chile presented with meningitis, which was confirmed to be caused by Chlamydia psittaci through cerebrospinal fluid quantitative real-time PCR and serology.
First-trimester pregnancy-associated breast cancer managed without pregnancy termination: a report with long-term follow-up.
A patient diagnosed with breast cancer in the first trimester opted to continue her pregnancy rather than terminate it. She underwent total mastectomy and axillary lymph node dissection, with chemotherapy initiated…
Gastric neuroendocrine tumours after prolonged proton pump inhibitor use.
A woman in her 40s with chronic gastro-oesophageal reflux disease had been on proton pump inhibitors for 20 years. She was diagnosed with gastric neuroendocrine tumours during an upper endoscopy.
Insights into diagnosis and management of giant adrenal pseudocysts.
A young man presented with headaches and mild anaemia, leading to imaging that revealed a giant left adrenal cystic lesion measuring 19×15×15 cm. Despite indeterminate CT findings, PET imaging suggested a benign nature.
Pharmacokinetic and Pharmacodynamic Drug-Drug Interactions Between Cofrogliptin and Metformin in Healthy Subjects: A Single-Center, Single-Arm, Phase I Study in China.
This single-center, single-arm Phase I study assessed drug-drug interactions between cofrogliptin and metformin in 22 healthy Chinese subjects.
A Phase I Study of Nimotuzumab Combined with Irinotecan in Chinese Patients with Advanced Solid Tumors.
This Phase I study assessed the pharmacokinetics and safety of nimotuzumab combined with irinotecan in Chinese patients with advanced solid tumors.
Meta-analysis of Maternal and Fetal Outcomes of Crimean-Congo Hemorrhagic Fever during Pregnancy.
This meta-analysis examined the maternal and fetal outcomes of Crimean-Congo hemorrhagic fever (CCHF) in 55 pregnancies. The study found a maternal mortality rate of 28.8% and a fetal loss rate of 57.4%.
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