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1998 articles
October 202624
Mastectomy and sentinel lymph node biopsy in a patient with left-sided breast cancer and Poland syndrome.
An elderly woman with left-sided Poland syndrome presented with breast cancer detected during routine imaging for malignant melanoma.
From Genomic Insight to Clinical Impact: Dramatic Response in RET Fusion-positive Pancreatic Cancer.
A 48-year-old woman with pancreatic ductal adenocarcinoma and liver metastases experienced a significant response to selpercatinib after genomic profiling revealed an NCOA4-RET fusion.
Multidisciplinary Treatment With Repeated Thermal Ablation for Multisite Metastatic Colon Cancer in an Elderly Patient.
An 81-year-old woman with a history of myocardial and cerebral infarctions presented with metastatic colon cancer, including multiple liver and ovarian metastases.
Primary malignant mesothelioma of the tunica vaginalis presenting as hydrocele: imaging pitfalls.
A man in his late 70s presented with a progressive, painless scrotal swelling initially diagnosed as a simple hydrocele via ultrasound.
Paraneoplastic dermatomyositis preceding detection of metastatic oesophageal squamous cell carcinoma after prolonged remission following pembrolizumab therapy.
A man in his late fifties with a history of treated oesophageal squamous cell carcinoma developed severe dermatomyositis after six years of remission.
Pembrolizumab plus Chemotherapy for Synchronous Multiple Primary Esophageal and Gingival Squamous Cell Carcinomas.
A 68-year-old man presented with synchronous squamous cell carcinomas of the esophagus and mandibular gingiva. He received pembrolizumab combined with cisplatin and 5-fluorouracil, leading to a clinical complete…
Pearls & Oy-sters: Diagnosis of Pediatric Tumefactive Multiple Sclerosis With MRI Biomarkers.
A 16-year-old boy presented with subacute headaches, cognitive difficulties, dizziness, blurry vision, right arm weakness, numbness, and gait issues.
Alpha-catenin Mutation-associated Synchronous Follicular Thyroid Carcinoma and Papillary Thyroid Carcinoma With Numerous Adenomatoid Nodules.
A 59-year-old woman with a history of breast cancer was found to have a thyroid nodule during a chest CT. Subsequent biopsies revealed synchronous minimally invasive follicular thyroid carcinoma and classic papillary…
Osimertinib plus Gefitinib in Patients with EGFR-Mutated Advanced Non-Small Cell Lung Cancer and EGFR (C797X) Mutation Following First-Line Osimertinib: ORCHARD.
The ORCHARD study was a phase II trial assessing the efficacy of osimertinib plus gefitinib in patients with EGFR-mutated advanced non-small cell lung cancer (NSCLC) and EGFR C797X mutation after progression on…
Pediatric Literacy Promotion for Latino Families by Texts and Referrals: A 3-Arm RCT.
This randomized controlled trial evaluated two strategies to enhance literacy promotion among 630 Latino caregiver-infant dyads.
Tuberculosis and persistent chylous ascites.
A late adolescent boy presented with fever, weight loss, and lymphadenopathy, leading to a diagnosis of extrapulmonary tuberculosis.
Surgical Resection of Metachronous Liver Metastases in Non-colorectal Non-neuroendocrine Gastrointestinal Cancers: Systematic Review and Meta-analysis.
This systematic review and meta-analysis evaluated the impact of surgical resection on overall survival in patients with metachronous liver metastases from non-colorectal non-neuroendocrine gastrointestinal cancers.
Association of Sarcopenia With Global, Motor, Cognitive, and Swallowing Function Prognosis in Stroke Patients: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the impact of sarcopenia on functional outcomes in stroke patients. Analyzing 36 cohort studies, it found that patients with sarcopenia had a significantly higher risk…
Human Infection with Japanese Encephalitis Virus Genotype V, China, 2025.
A human case of Japanese encephalitis virus genotype V (JEV GV) was confirmed in China through serological testing, sequencing, and quantitative reverse transcription PCR.
Incisional Negative Pressure Wound Therapy for Prevention of Surgical Site Infection: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis pooled 85 randomised clinical trials involving 16,980 adults with primarily closed surgical incisions to compare incisional negative pressure wound therapy (iNPWT) with standard…
Exposure-Response Analyses of Ropeginterferon Alfa-2b in Essential Thrombocythemia.
This meta-analysis examined the population pharmacokinetics and pharmacodynamics of ropeginterferon alfa-2b in patients with essential thrombocythemia (ET).
Mediation Analysis of Urine Osmolality and Response to Tolvaptan in Autosomal Dominant Polycystic Kidney Disease: A Post Hoc Assessment.
This post hoc analysis of the TEMPO 3:4 randomized controlled trial evaluated urine osmolality (Uosm) as a biomarker for long-term response to tolvaptan in patients with autosomal dominant polycystic kidney disease…
Efficacy and Safety of PD-1/PD-L1 Inhibitors Combined With Anti-Angiogenic Tyrosine Kinase Inhibitors for Recurrent or Metastatic Nasopharyngeal Carcinoma: A Systematic Review and Single-Arm Meta-Analysis.
This systematic review and meta-analysis evaluated the efficacy and safety of PD-1/PD-L1 inhibitors combined with anti-angiogenic tyrosine kinase inhibitors in 357 patients with recurrent or metastatic nasopharyngeal…
Acute Motor and Sensory Axonal Neuropathy Variant of Guillain-Barré Syndrome: A Nurse-Led Intensive Care Case Report.
A 40-year-old man presented with acute quadriparesis and respiratory distress after a febrile illness. He was diagnosed with acute motor and sensory axonal neuropathy, complicated by multiple infections including…
Hereditary Spastic Paraplegia Type 11: A Comprehensive Case Report.
An 18-year-old woman with no significant medical history presented with a 2-year history of progressive weakness and stiffness in both lower limbs, leading to difficulty in walking.
Giredestrant plus Everolimus in Advanced Breast Cancer.
This phase 3 randomized controlled trial evaluated the efficacy of giredestrant plus everolimus versus standard endocrine therapy plus everolimus in patients with ER-positive, HER2-negative advanced breast cancer who…
Digital Health Technologies for Risk Factor Management and Secondary Prevention After Stroke: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the effectiveness of digital health interventions for managing vascular risk factors in stroke survivors.
Ultrasound-Guided Dorsal Penile Nerve Block Reduces Perioperative Opioid Requirements in Pediatric Circumcision: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the effectiveness of ultrasound-guided versus landmark-based dorsal penile nerve block (DPNB) in reducing opioid requirements during pediatric circumcision.
A Mysterious Case of Giant Scalp Devil's Horn with Intracranial Extension Removed by Surgical Excision.
A 60-year-old male presented with altered consciousness, chronic headaches, blurred vision, and scalp swelling. Imaging revealed a giant cutaneous horn in the scalp with underlying bony erosion and intracranial…
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