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1999 articles

October 202624

Clinical ResearchDermatology

Contact Allergens Associated With Nummular Eczema: A Systematic Review.

This systematic review examined the association between contact allergens and nummular eczema (NE) by analyzing 10 observational studies.

J Drugs DermatolOct 1, 2026Read summary
Case ReportGeneral Surgery

Temporary Mesocaval Bypass During Pancreaticoduodenectomy for Pancreatic Cancer With Portal Vein Occlusion: A Case Report.

A 79-year-old man with locally advanced pancreatic cancer and complete portal vein occlusion underwent pancreaticoduodenectomy after showing a favorable response to preoperative therapy.

Anticancer ResOct 1, 2026Read case
Case ReportMedical Genetics

A Novel BORCS5 Loss-Of-Function Variant in a Patient With a Rare Neurodevelopmental Disorder.

The BORCS5 is an important and critical component of the BLOC-one-related complex (BORC), involved in kinesin-dependent anterograde lysosomal transport.

Int J Dev NeurosciOct 1, 2026Read case
Case ReportPlastic Surgery

Maxillofacial prosthetic management of oral incompetence following commando surgery and partial maxillectomy: A clinical report.

A patient who underwent commando surgery and partial maxillectomy for squamous cell carcinoma presented with significant facial defects, oral incompetence, and discomfort.

J Indian Prosthodont SocOct 1, 2026Read case
Case ReportPediatrics

Hereditary TTP and Hemolytic Anemia in Newborns.

This case report discusses three siblings diagnosed with hereditary thrombotic thrombocytopenic purpura (hTTP) due to ADAMTS13 deficiency, presenting with severe jaundice at birth.

PediatricsOct 1, 2026Read case
Clinical ResearchInfectious Diseases

HIV-associated pulmonary arterial hypertension: improving survival despite persistent treatment gaps - a systematic review and meta-analysis.

This systematic review and meta-analysis examined 12 cohorts of patients with HIV-associated pulmonary arterial hypertension (HIV-PAH), totaling 537 individuals.

AIDSOct 1, 2026Read summary
Clinical ResearchPhysical Medicine & Rehabilitation

Dose Considerations and Generalization Following Script Training for Poststroke Aphasia: A Randomized Factorial Clinical Trial.

This single-site, single-blind, 2 × 2 factorial randomized controlled trial examined how script length and session frequency affect treatment outcomes in 85 people with chronic poststroke aphasia.

J Speech Lang Hear ResOct 1, 2026Read summary
Clinical ResearchEmergency Medicine

Evaluating CPR Breast Attachment Impact on EMT Training: A Randomized Controlled Trial.

This randomized controlled trial evaluated the impact of the ReviveHer breast attachment on EMT students' willingness and comfort in performing CPR on breasted and nonbreasted individuals.

Simul HealthcOct 1, 2026Read summary
Clinical ResearchGeneral Surgery

The Use of Deliberate Practice in Simulation-Based Surgical Training for Open General and Subspeciality Surgery: A Systematic Review.

This systematic review evaluates the integration of deliberate practice (DP) in simulation-based surgical training (SBST) for open general and subspecialty surgery.

Simul HealthcOct 1, 2026Read summary
Clinical ResearchNeurologyOpen access

Systematic Review and Meta-Analysis on Rescue Stenting for Large Vessel Occlusion Due to Underlying Intracranial Atherosclerotic Stenosis.

This systematic review and meta-analysis evaluated the efficacy and safety of rescue stent placement in patients with large vessel occlusion (LVO) due to intracranial atherosclerotic stenosis (ICAS).

AJNR Am J NeuroradiolOct 1, 2026Read summary
Clinical ResearchEmergency Medicine

"I Don't Speak English Well." Do Language Barriers Affect Automated External Defibrillator Use? A Randomized Simulation Study With Spanish-Speaking Laypeople.

This randomized controlled trial assessed the impact of language barriers on automated external defibrillator (AED) use among 50 Spanish-speaking university students.

Simul HealthcOct 1, 2026Read summary
Clinical ResearchNeurologyOpen access

Temporal Net Water Uptake Evolution and Its Association with Functional Outcome in Acute Ischemic Stroke.

This multicenter randomized controlled trial examined the relationship between temporal changes in net water uptake (NWU) and functional outcomes in 115 patients with acute ischemic stroke.

AJNR Am J NeuroradiolOct 1, 2026Read summary
Clinical ResearchFamily Medicine

Primary care practitioners' experiences managing urinary tract infections: a qualitative evidence synthesis.

This qualitative evidence synthesis explored the experiences of primary care practitioners (PCPs) managing urinary tract infections (UTIs) across various international settings.

Br J Gen PractOct 1, 2026Read summary
Clinical ResearchHematology

Management of Antineutrophil Cytoplasmic Antibody-Associated Alveolar Hemorrhage: A Bayesian Reanalysis of the PEXIVAS Trial.

This Bayesian reanalysis of the PEXIVAS trial focused on adults with antineutrophil cytoplasmic antibody-associated vasculitis and diffuse alveolar hemorrhage (DAH).

J RheumatolOct 1, 2026Read summary
Clinical ResearchRheumatology

Follow-Up 18F-Fluorodeoxyglucose Positron Emission Tomography in Treated Patients With Giant Cell Arteritis: A Systematic Review and Metaanalysis.

This systematic review and meta-analysis evaluated the use of 18F-fluorodeoxyglucose (FDG) PET to monitor disease activity in patients with large-vessel giant cell arteritis (LV-GCA) who showed clinical improvement…

J RheumatolOct 1, 2026Read summary
Clinical ResearchOncology (Medical)

[18F]RCCB6 PET/CT in Diagnosing Clear-Cell Renal Cell Carcinomas: A Prospective Comparison Study with [18F]FDG PET/CT and Conventional Imaging.

[18F]RCCB6 PET/CT was evaluated in a single-center phase II trial for detecting metastases in clear-cell renal cell carcinoma (ccRCC).

Cancer DiscovOct 1, 2026Read summary
Clinical ResearchHematology

Ziftomenib with venetoclax and azacitidine for relapsed/refractory NPM1-mutated acute myeloid leukemia.

The KOMET-007 phase 1 trial evaluated the combination of ziftomenib with venetoclax and azacitidine in adults with relapsed/refractory NPM1-mutated acute myeloid leukemia (AML).

BloodOct 1, 2026Read summary
Clinical ResearchRheumatology

Bimekizumab Long-Term Safety and Efficacy Across the Spectrum of Axial Spondyloarthritis Over 3 Years: Results From 2 Phase III Studies.

This study evaluated the long-term safety and efficacy of bimekizumab, an IL-17A and IL-17F inhibitor, in patients with axial spondyloarthritis over 3 years.

J RheumatolOct 1, 2026Read summary
Clinical ResearchPsychiatry

Irritability in the Mix: An Exploratory Study of the Role of Irritability in Characterising Mood Disorders.

This randomized controlled trial explored the relationship between irritability and mixed states in 82 patients with bipolar disorder over 18 months.

Bipolar DisordOct 1, 2026Read summary
Case ReportPediatricsOpen access

Fibrin-Heparin-Coated Intracranial Stents as Salvage Therapy in Pediatric Focal Cerebral Arteriopathy-Inflammatory Type.

A 13-year-old boy presented with progressive arterial ischemic stroke due to focal cerebral arteriopathy inflammatory type.

AJNR Am J NeuroradiolOct 1, 2026Read case
Clinical ResearchOncology (Medical)

A Randomized, Nivolumab-Controlled, Phase II Biomarker Study of Lomvastomig and Tobemstomig in Advanced or Metastatic Squamous Cell Carcinoma of the Esophagus.

This phase II randomized controlled trial evaluated the efficacy of bispecific antibodies lomvastomig and tobemstomig against nivolumab in 190 checkpoint inhibitor-naïve patients with advanced esophageal squamous cell…

Clin Cancer ResOct 1, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Avutometinib, Abemaciclib, and Fulvestrant in Patients with HR+/HER2- Metastatic Breast Cancer Previously Treated with CDK4/6 Inhibitor: A Single-Arm Phase I Trial.

This single-arm phase I trial evaluated the combination of avutometinib, abemaciclib, and fulvestrant in 16 patients with HR+/HER2- metastatic breast cancer who had previously progressed on CDK4/6 inhibitors.

Clin Cancer ResOct 1, 2026Read summary
Clinical ResearchGeriatrics

Perioperative Safety and Effectiveness of Laparoscopic Heller Myotomy in Elderly Patients: Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated the perioperative safety and effectiveness of laparoscopic Heller myotomy (LHM) in patients aged 65 years or older.

Surg Laparosc Endosc Percutan TechOct 1, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Tumor-Infiltrating Lymphocytes as a Predictor of Adjuvant Avelumab Efficacy in Patients with High-risk Triple-Negative Breast Cancer.

This phase III randomized controlled trial investigated the prognostic and predictive value of tumor-infiltrating lymphocytes (TIL) in 466 patients with high-risk early triple-negative breast cancer (TNBC) receiving…

Clin Cancer ResOct 1, 2026Read summary

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