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2000 articles
September 202624
Effects of exercise interventions on gait, motor function, and balance in patients with Parkinson's disease: A meta-analysis with clinical implications.
This meta-analysis evaluated the effects of exercise interventions on gait, motor function, and balance in 714 patients with Parkinson's disease.
Critical Kennedy's disease with Guillain-Barré syndrome and respiratory failure: A case report.
A 61-year-old man with a 35-year history of Kennedy disease presented with acute respiratory failure, dysphagia, and progressive dyspnea.
Pure Red Cell Aplasia Following Neoadjuvant Docetaxel/Carboplatin/Trastuzumab (TCbH) in a 45‑Year‑Old Woman With Breast Cancer Successfully Treated With Cyclosporine.
A 45-year-old woman with HER2-positive breast cancer developed pure red cell aplasia (PRCA) after neoadjuvant treatment with docetaxel/carboplatin/trastuzumab.
Progression-free survival and objective response rate as a surrogate end point for overall survival in metastatic renal cell carcinoma: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the validity of progression-free survival (PFS) and objective response rate (ORR) as surrogate endpoints for overall survival (OS) in randomized controlled trials of…
Bispectral index during remimazolam versus propofol sedation at matched depths: a randomized, double-blind crossover trial in healthy volunteers.
This randomized, double-blind crossover trial evaluated the bispectral index (BIS) during remimazolam versus propofol sedation in 16 healthy volunteers.
Accuracy of Artificial Intelligence in Diagnosing Obstructive Sleep Apnea Using Photoplethysmography: Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the diagnostic accuracy of AI-based methods using photoplethysmography (PPG) for obstructive sleep apnea (OSA) in adults.
Fasting-induced metabolic reprogramming as a therapeutic vulnerability in cancer: a systematic mechanistic review of in vitro evidence.
This systematic review evaluated in vitro studies on fasting and fasting-mimicking interventions in cancer cell models. It found that fasting consistently reduced IGF-1 signaling and inhibited key metabolic pathways…
Sarcopenia Is Associated With Severe Treatment Toxicity and Mortality in Older Adults With Advanced Cancer: A Secondary Analysis.
This secondary analysis of a randomized controlled trial examined the impact of sarcopenia on treatment outcomes in 161 older adults (≥ 70 years) with advanced cancer.
Lower Limb Necrotizing Soft Tissue Infection Associated with Corynebacterium minutissimum in an Adolescent: A Case Report and Surgical Management.
A 14-year-old boy presented with progressive ulceration, swelling, and malodor in the left lower leg, leading to a diagnosis of necrotizing soft tissue infection (NSTI).
Multimorbidity and the risk of depression: a systematic review of cohort studies.
This systematic review evaluated the longitudinal association between multimorbidity and the risk of developing depression, analyzing 17 cohort studies.
The reduction in blood pressure required to reduce arterial stiffness components in SPRINT: a randomized controlled trial.
This analysis of the multicentre SPRINT randomised controlled trial examined whether blood pressure changes were associated with changes in arterial stiffness components over 1 year.
Intraosseous versus intravenous access in adult out-of-hospital cardiac arrest: a Bayesian secondary analysis of the PARAMEDIC-3 randomised controlled trial.
This pre-planned Bayesian secondary analysis of the PARAMEDIC-3 randomised controlled trial compared intraosseous-first with intravenous-first vascular access in adults with out-of-hospital cardiac arrest requiring…
Unusual pelvic mass in a young adult: prostatic Ewing's sarcoma with distant metastases.
A man in his 20s presented with urinary obstruction, constipation, and leg pain. Imaging revealed a bulky pelvic mass from the prostate, leading to bilateral hydroureteronephrosis.
Urethral syringocele: a rare cause of recurrent urinary tract infections.
A man in his early 30s presented with dysuria, urinary frequency, urethral discharge, and cloudy urine for three weeks, unresponsive to antibiotics. He developed a tender perineal swelling.
Fatal spontaneous bilateral extradural hematoma with swirl sign in a child with sickle cell disease: lessons from delayed surgical access at a tertiary center.
A 13-year-old girl with homozygous sickle cell disease presented with sudden altered consciousness and left hemiparesis, showing a Glasgow coma scale of 9.
Pancreatic arteriovenous malformations as a manifestation of hereditary haemorrhagic telangiectasia (Rendu-Osler-Weber disease): a systematic review.
This systematic review examined pancreatic arteriovenous malformations (AVMs) in patients with hereditary hemorrhagic telangiectasia (HHT), analyzing 19 cases from 13 studies.
Monolateral rail fixator in paediatric femoral osteomyelitis can be a patient-friendly alternative to conventional fixator.
A 6-year-old boy with chronic femoral osteomyelitis presented with pus discharge, pain, and difficulty walking after an initial drainage procedure.
Effectiveness of digital interventions for menopausal symptoms and cardiometabolic outcomes among women undergoing the menopausal transition: A systematic review and meta-analyses.
This systematic review and meta-analysis assessed digital health interventions for menopausal symptoms and cardiometabolic outcomes in women undergoing the menopausal transition.
A case report on the management of sepsis complicated by eroded mixed hemorrhoids following breast cancer chemotherapy.
A 51-year-old female with stage IIIA breast cancer developed septicemia and eroded mixed hemorrhoids following chemotherapy. She presented with severe neutropenia and a high fever.
Study on blueberries, protein and exercise for improving frailty and cardiovascular disease (STRONG): protocol for a parallel-group randomised controlled superiority trial in older Nova Scotians.
The STRONG study is a parallel-group randomized controlled trial aimed at assessing the impact of a year-long intervention involving blueberries, protein, and exercise on frailty and cardiovascular health in 240 older…
Turning distress into distraction: using virtual reality during penicillin injections for rheumatic fever.
This phase IIA clinical trial evaluated the use of immersive virtual reality (VR) during subcutaneous penicillin injections in 10 participants aged 9-20 years with acute rheumatic fever.
The Role of Greenness in Heat-Related Mortality: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis examined the relationship between greenness and heat-related mortality across various countries.
Acute oral Chagas disease following armadillo blood ingestion: a case report.
A 70-year-old man from rural Colombia presented with atrial fibrillation, dyspnea, and palpitations. A blood smear identified Trypanosoma cruzi, confirmed by molecular testing, linked to his ingestion of armadillo blood…
Possible correlation between Mycobacterium abscessus subsp. massiliense spondylodiscitis and spinal anesthesia: Diagnostic and therapeutic challenges.
A 57-year-old man experienced back pain following spinal anesthesia for prostate surgery. Six months later, he underwent decompressive laminectomy, with initial cultures negative for mycobacteria.
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