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2000 articles
October 202624
Cold and Room-Temperature Platelets in Cardiac Surgery: The CHIPS Randomized Clinical Trial.
The phase 3, multicenter, randomized CHIPS trial compared cold-stored platelets (CSPs; up to 21 days) with room-temperature platelets (RTPs; up to 7 days) in pediatric and adult patients receiving platelet transfusions…
Elinzanetant in postmenopausal women with sleep disturbance: results from the randomized, phase II NIRVANA study.
The phase II NIRVANA randomised trial assessed elinzanetant versus placebo in 110 postmenopausal women aged 40–65 years with moderate-to-severe vasomotor symptoms and objectively measured sleep disturbance.
Successful Kidney Transplantation Under Combined Spinal-Epidural Anesthesia in a Patient With a History of Left Pneumonectomy Due to Bronchiectasis.
A 33-year-old man with end-stage kidney disease from biopsy-proven AA amyloidosis was assessed for preemptive living-donor kidney transplantation.
Effect of diet-induced plasma ceramide on human in vivo microvascular endothelial function.
This double-blind, randomized crossover trial examined whether a meal-induced rise in plasma ceramides impairs in vivo microvascular function in 23 healthy young adults.
PTCD and Peroral Electronic Cholangioscopy with Holmium Laser Lithotripsy for CBD Stones in a Super-Elderly Patient Post-Billroth II Gastrojejunostomy.
The management of impacted common bile duct stones in patients with prior Billroth II gastrectomy poses unique challenges. Altered gastrointestinal anatomy renders duodenoscope passage and biliary cannulation during…
Six-month supervised telerehabilitation combining pilates-based therapeutic exercise and self-myofascial release in adults with fibromyalgia: a randomized controlled trial.
This two-arm randomized controlled trial evaluated a six-month supervised home-based telerehabilitation programme in 68 adults with fibromyalgia confirmed by 2016 ACR criteria.
Life-Threatening Ventricular Tachycardia and Transient Brugada-Like Electrocardiographic Abnormalities Caused by Severe Hyperkalemia Due to Urinary Retention in a 55-Year-Old Man.
A 55-year-old man without known cardiovascular disease presented with palpitations, dyspnea, and diaphoresis, then developed hemodynamically unstable sustained wide-QRS ventricular tachycardia with recurrent episodes…
Hemi-see-saw nystagmus with superimposed pendular oculopalatal tremor: case report and systematic review.
A 30-year-old man with a pontomedullary arteriovenous malformation presented with pendular hemi-see-saw nystagmus, right one-and-a-half syndrome, gaze-evoked nystagmus, ocular tilt reaction, incomplete Horner syndrome…
Atypical presacral masses in Currarino syndrome: a case series.
The report describes three patients with Currarino syndrome, a congenital condition involving a sacral anomaly, anorectal malformation, and presacral mass.
Feasibility of Online and On-Site Physical Activity Delivery Among Older Adults: Mixed Methods Pilot Randomized Controlled Trial.
This unblinded, site-cluster-randomized mixed methods pilot trial assessed the feasibility of a 26-week Otago physical activity program delivered online or in person to community-dwelling adults aged 60 years or older…
Prevalence and genotype distribution of norovirus and rotavirus among children under five with diarrheal infection in lower-middle-income countries after Rotavirus vaccine introduction: A systematic review and meta-analysis.
This systematic review and meta-analysis assessed norovirus and rotavirus prevalence and genotype distribution among children under five with diarrheal infection in low- and middle-income countries after rotavirus…
Clinicopathologic Evaluation of Amyloid Clearance in Alzheimer Disease.
A man in his 50s with mild cognitive impairment and the Alzheimer disease risk-associated p.R47H TREM2 variant received 30 doses of aducanumab (cumulative dose 280 mg/kg) over 4.5 years in a clinical trial.
Clinical translation of polymeric microneedles for bioactive nanovesicle delivery in hypertrophic scar remodeling.
This prospective, single-center, open-label, single-arm study evaluated a 12-week protocol combining microplasma radiofrequency, poly(L-lactic acid) microneedles, and topical milk-derived bioactive nanovesicles in 26…
Successful management of long-term venovenous ECMO for severe PARDS in a child with acute lymphoblastic leukemia.
A 5-year-old boy with low-risk B-cell acute lymphoblastic leukemia developed severe, refractory pediatric acute respiratory distress syndrome during induction therapy, with profound hypoxemia.
Post-Stroke Depression and Determinants in Ethiopia; A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis examined the prevalence and determinants of post-stroke depression (PSD) in Ethiopia, combining findings from eight studies.
Network Meta-Analysis: Treatments for Acute Alcohol-Associated Hepatitis.
This systematic review and network meta-analysis compared treatments for alcohol-associated hepatitis (AH) using 90-day survival as the primary outcome.
Cost comparison of the ShangRing device versus Mogen clamp for early infant male circumcision in Sub-Saharan Africa.
This cost comparison alongside a randomized controlled trial assessed early infant male circumcision using the ShangRing (SR) versus the Mogen clamp (MoC) among infants aged 0–60 days in Kenya, Tanzania, and Uganda.
Impact of a Dynamic Visualized Pain Assessment Tool on Pediatric Pain Management: A Stepped-Wedge Cluster Randomized Trial.
This stepped-wedge cluster randomized trial evaluated a dynamic visualized pain assessment tool across five clinical wards, involving 15 infants and 45 video segments spanning baseline, procedural pain, and…
Opioid-free versus opioid-based anesthesia for robot-assisted radical prostatectomy: a single-center randomized controlled trial.
This single-center randomized controlled trial compared opioid-free anesthesia (dexmedetomidine plus ketamine) with remifentanil-based anesthesia in adult men undergoing robot-assisted radical prostatectomy.
Fibro-Inflammatory Signaling, Fibrosis, and Microvascular Ischemia as Convergent Translational Substrates of Sudden Cardiac Death in Hypertrophic Cardiomyopathy: A Systematic Review.
This systematic translational review examined whether fibro-inflammatory signaling, fibrosis, and microvascular ischemia converge as substrates for ventricular arrhythmia and sudden cardiac death in hypertrophic…
Extensive recurrent pterygium following photorefractive keratectomy: a case report.
A healthy 39-year-old man developed an extensive recurrent pterygium three months after uneventful photorefractive keratectomy (PRK), having undergone primary pterygium surgery two months before PRK.
Integrated physical, cognitive and psychological rehabilitation following multiple ACL reconstructions in a professional handball player: a case report.
A 31-year-old professional handball player with two ACL reconstructions, meniscal repairs, a postoperative knee infection, and multiple arthroscopic procedures had persistent knee instability, pain, and psychological…
Bee Sting-Associated Kounis Syndrome Presenting as Myocardial Infarction: A Case Report and Systematic Review with Age-Based Analysis.
A 44-year-old man presented with myocardial infarction after a probable bee sting-associated allergic reaction and was considered to have Kounis syndrome, an acute coronary syndrome linked to hypersensitivity.
Machine Learning, Radiomics, and Clinical Models Predicting Checkpoint Inhibitor Pneumonitis in Lung Cancer: A Systematic Review and Meta-analysis.
This systematic review and meta-analysis assessed machine-learning, radiomics, deep-learning, and clinical models for predicting checkpoint inhibitor pneumonitis in people with lung cancer.
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