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2000 articles

October 202624

Clinical ResearchPediatrics

Haemodynamic and neurophysiological assessments for 2-year outcome prediction in neonates with hypoxic-ischaemic encephalopathy treated with therapeutic hypothermia: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the prognostic accuracy of amplitude-integrated electroencephalography (aEEG), cerebral near-infrared spectroscopy (cNIRS), and targeted neonatal echocardiography…

BMJ Paediatr OpenOct 3, 2026Read summary
Clinical ResearchUrologyOpen access

Robot-assisted versus non-robotic partial nephrectomy for completely endophytic renal tumors: a systematic review and meta-analysis.

This systematic review and meta-analysis compared robot-assisted partial nephrectomy (RAPN) with laparoscopic (LPN) and open partial nephrectomy (OPN) for completely endophytic renal tumors (CERTs) in 896 patients.

J Robot SurgOct 3, 2026Read summary
Clinical ResearchNeurologyOpen access

Brain-Derived Neurotrophic Factor Val66Met Polymorphism and Cognitive Outcome after Stroke: A Systematic Review.

This systematic review examined the association between the BDNF Val66Met polymorphism and cognitive outcomes in 2,494 adults post-stroke.

Transl Stroke ResOct 3, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Effects of exercise and educational programs on long-term quality of life, anxiety, and depression in breast cancer survivors: an exploratory secondary analysis of the Setouchi breast project-10 randomized controlled trial.

This exploratory secondary analysis of a randomized controlled trial examined exercise and education for 342 patients with stage 0–III breast cancer within one year of completing treatment.

Breast CancerOct 3, 2026Read summary
Clinical ResearchNeurology

HD-tACS at 40 Hz improves consciousness and brain connectivity in prolonged disorders of consciousness: a randomized sham-controlled clinical trial.

This randomized, sham-controlled clinical trial evaluated 40 Hz and 4 Hz high-definition transcranial alternating current stimulation (HD-tACS) in 60 patients with prolonged disorders of consciousness.

NeuroimageOct 3, 2026Read summary
Clinical ResearchObstetrics & GynecologyOpen access

Determinants of delayed antenatal visit attendance in rural Burkina Faso: a cross-sectional study.

This cross-sectional study assessed delayed antenatal care (ANC) attendance among pregnant women in rural Burkina Faso. Out of 2480 women with data, 90.6% attended their first ANC visit after the 14th week of gestation.

BMC Pregnancy ChildbirthOct 3, 2026Read summary
Clinical ResearchGeriatrics

Vitamin D Supplementation and Mortality in the Elderly: A Review of a Meta-Analysis of Randomized Controlled Trials Using the REB Method.

This meta-analysis reviewed 25 randomized controlled trials (RCTs) to evaluate the impact of vitamin D supplementation on mortality in individuals aged 75 and older.

Fundam Clin PharmacolOct 3, 2026Read summary
Clinical ResearchNephrology

Bone Anabolic Treatment in Patients With Chronic Kidney Disease: A Systematic Review.

This systematic review evaluated the efficacy and safety of anabolic parathyroid hormone (PTH) treatments in patients with chronic kidney disease (CKD) Stages 4-5D.

Basic Clin Pharmacol ToxicolOct 3, 2026Read summary
Clinical ResearchPathology (Anatomic & Clinical)

Concordance of Microbiological and Histopathological Examination of Bone Biopsies in Diagnosing Diabetic Foot Osteomyelitis, a Systematic Review.

This systematic review evaluated the diagnostic concordance of histopathology and microbiology in bone biopsies from 308 adults with diabetic foot osteomyelitis (DFO).

J Foot Ankle ResOct 3, 2026Read summary
Case ReportOncology (Medical)Open access

Complete Regression of 11 Hepatic Metastases in Metastatic Pancreatic Adenosquamous Carcinoma and the Role of GPT in Patient Navigation.

A 65-year-old man with resected pancreatic adenosquamous carcinoma (pT3 pN2, R0) had 11 liver lesions interpreted as metastases on MRI.

Int Med Case Rep JOct 3, 2026Read case
Case ReportInfectious DiseasesOpen access

Blackwater Fever Complicated by Severe Acute Kidney Injury and a Therapeutic Dilemma: A Case Report from Niger.

A 50-year-old woman with persistent Plasmodium falciparum infection and repeated antimalarial treatment, including artesunate, presented with fever, jaundice, and severe acute kidney injury (serum creatinine 1104.1…

Int Med Case Rep JOct 3, 2026Read case
Case ReportHematologyOpen access

Concurrent presentation of distinct extranodal and splenic marginal zone lymphomas.

A patient was diagnosed with both extranodal marginal zone lymphoma (EMZL) of the ocular adnexa and splenic marginal zone lymphoma (SMZL).

J HematopOct 2, 2026Read case
Clinical ResearchPediatrics

Impact of digital health interventions in improving pediatric immunization coverage and timeliness in low- and middle-income countries: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed randomized controlled trials of digital interventions to improve pediatric vaccination outcomes in low- and middle-income countries.

VaccineOct 2, 2026Read summary
Clinical ResearchAnesthesiologyOpen access

Effects of stellate ganglion block on postoperative sleep disturbance: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the effects of stellate ganglion block (SGB) on postoperative sleep disturbance in 734 participants from 10 randomized controlled trials.

Sleep BreathOct 2, 2026Read summary
Clinical ResearchPediatricsOpen access

Comparison of Molecular Methods With Culture for Identifying Microbial Etiology in Pediatric Empyema Thoracis: A Systematic Review of Diagnostic Test Accuracy.

This systematic review evaluated the diagnostic accuracy of molecular methods versus culture for identifying microbial etiology in pediatric empyema thoracis.

Indian PediatrOct 2, 2026Read summary
Clinical ResearchMedical GeneticsOpen access

Genotype-Phenotype Relationships in Patients Carrying Biallelic FDXR Pathogenic Variants-New Cases and Systematic Review.

Biallelic pathogenic FDXR variations were identified in 2017 as being responsible for sensorial neuropathies. The first reported patients suffered from auditory and optic sensorineural impairments (ANOA, MIM #617717).

Hum MutatOct 2, 2026Read summary
Clinical ResearchNeurosurgeryOpen access

Non-Ischemic Cerebral Enhancing (NICE) lesions after flow diversion for intracranial aneurysms: a systematic review with case-level synthesis.

This PROSPERO-registered systematic review synthesized reports of delayed non-ischemic cerebral enhancing (NICE) lesions after flow-diverter treatment of intracranial aneurysms; heterogeneity precluded meta-analysis.

BMC NeurolOct 2, 2026Read summary
Clinical ResearchEndocrinology

Native collagen matrix plus PHMB antimicrobial in hard-to-heal diabetic foot ulcers: results from the PREPARE randomised controlled trial.

The PREPARE prospective, multicentre randomised controlled trial compared purified native type 1 collagen extracellular matrix plus polyhexamethylene biguanide (PCMP) with standard care (SoC) alone in patients with…

J Wound CareOct 2, 2026Read summary
Case ReportGastroenterologyOpen access

Markedly Elevated CA 19-9 in Type I Mirizzi Syndrome in the Absence of Malignancy: A Case Report.

A 50-year-old man presented with acute obstructive jaundice, fever, and right upper quadrant pain; serum CA 19-9 was 1000 U/mL.

Int Med Case Rep JOct 2, 2026Read case
Clinical ResearchFamily Medicine

Implementation of Communication Disability Documentation and Accommodations in Primary Care: A Pragmatic Type III Hybrid Implementation-Effectiveness Trial Protocol.

This article describes the protocol for the DECA study, a pragmatic Type III hybrid implementation-effectiveness trial of communication disability (CD) documentation and accommodation processes in primary care.

J Speech Lang Hear ResOct 2, 2026Read summary
Clinical ResearchPsychiatryOpen access

A Randomized Controlled Trial of a Digital Stepped-Care Program to Reduce Anxiety and Depressive Symptoms Among Long-Term Care Workers With Psychological Distress: The REPICAL Study.

The REPICAL study evaluated a digital stepped-care program aimed at reducing anxiety and depressive symptoms among long-term care workers (LTCWs) in Catalonia, Spain.

Depress AnxietyOct 2, 2026Read summary
Case ReportUrologyOpen access

Isolated Prostatic Tuberculosis Coexisting with Benign Prostatic Hyperplasia: A Case Report.

A 70-year-old man presented with one month of lower urinary tract symptoms and recurrent urinary retention requiring repeated catheterization.

Int Med Case Rep JOct 2, 2026Read case
Clinical ResearchOncology (Medical)

Hypofractionated 44 Gy in 20 fractions versus conventional chemoradiation in cervical cancer: 2-year results of the randomized HYPOCx-iRex trial with an exploratory pooled analysis of a single-institute EMBRACE-II cohort.

The randomized HYPOCx-iRex trial compared hypofractionated chemoradiation (44 Gy in 20 fractions) with conventional chemoradiation (45 Gy in 25 fractions) for locally advanced cervical cancer; an exploratory pooled…

BrachytherapyOct 2, 2026Read summary
Clinical ResearchGastroenterologyOpen access

Clinical outcomes of early versus standard liver transplantation in patients with alcohol-related liver disease: a meta-analysis.

This meta-analysis compared early and standard liver transplantation in patients with alcohol-related liver disease. It included 12 studies and 2323 patients.

Langenbecks Arch SurgOct 2, 2026Read summary

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