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2000 articles

October 202624

Clinical ResearchGeneral Surgery

A systematic review and meta-analysis of preoperative MRI-based pelvimetry in predicting surgical difficulty in rectal cancer: Implications for personalised surgical planning.

This systematic review and meta-analysis evaluated the role of MRI-based pelvimetry in predicting surgical difficulty during total mesorectal excision (TME) for rectal cancer, involving 8,364 patients across 36 studies.

Colorectal DisOct 1, 2026Read summary
Case ReportGastroenterology

A novel variant of pancreaticobiliary maljunction: Complete opening of the common bile duct into the duct of Santorini in a patient with pancreas divisum.

A 20-year-old woman with recurrent cholestasis and acute pancreatitis presented with fever, jaundice, and abdominal pain; laboratory findings supported cholangitis and pancreatitis.

Ulus Travma Acil Cerrahi DergOct 1, 2026Read case
Clinical ResearchEndocrinologyOpen access

Reporting Gaps in mHealth Intervention Studies for Adults With Diabetes: Systematic Review.

This systematic review evaluated the reporting completeness of 144 randomized controlled trials (RCTs) on mHealth interventions for adults with diabetes using the mERA checklist.

JMIR Mhealth UhealthOct 1, 2026Read summary
Clinical ResearchCardiology

Quercetin in Myocardial Ischemia-Reperfusion Injury: Mechanistic Evidence, Cardioprotective Effects, and Translational Challenges.

This systematic review assessed the cardioprotective effects of quercetin in myocardial ischemia-reperfusion (I/R) injury, primarily in preclinical studies.

J Biochem Mol ToxicolOct 1, 2026Read summary
Case ReportNeurosurgery

How I do it: meningioangiomatosis of the sylvian fissure. The need for a tailored functional neurosurgery.

A patient with drug-resistant epileptic seizures presented with meningioangiomatosis located in the right sylvian fissure, affecting the M1-M2 segments of the right middle cerebral artery.

Acta Neurochir (Wien)Oct 1, 2026Read case
Clinical ResearchPlastic Surgery

Hair Follicle-Derived Grafting for Chronic Cutaneous Wounds: A Systematic Review of Clinical Outcomes.

This systematic review evaluated the clinical outcomes of hair follicle-derived grafting techniques for chronic cutaneous wounds, analyzing 16 studies with 239 patients.

Int Wound JOct 1, 2026Read summary
Clinical ResearchCardiology

Efficacy and Safety of Lorundrostat for Uncontrolled and Treatment-resistant Hypertension: A Systematic Review and Meta-analysis of Randomized Controlled Trials.

This systematic review and meta-analysis evaluated the efficacy and safety of lorundrostat in adults with uncontrolled or treatment-resistant hypertension.

J Cardiovasc PharmacolOct 1, 2026Read summary
Clinical ResearchCardiology

Efficacy and Safety of CETP Inhibitors in Patients With Atherosclerotic Cardiovascular Disease: A Systematic Review and Meta-analysis of Randomized Controlled Trials.

This systematic review and meta-analysis evaluated the efficacy and safety of cholesteryl ester transfer protein (CETP) inhibitors in 62,565 patients with atherosclerotic cardiovascular disease.

J Cardiovasc PharmacolOct 1, 2026Read summary
Clinical ResearchHematology

Lenalidomide-Related Diarrhea in Patients with Multiple Myeloma Is Associated with Gut Microbiota Dysbiosis and Disruption of the Bile Acid Pool.

This Phase II randomized controlled trial investigated the relationship between gut microbiota dysbiosis, bile acid pool disruption, and lenalidomide-related diarrhea (LRD) in patients with multiple myeloma.

Clin Cancer ResOct 1, 2026Read summary
Clinical ResearchCardiology

Prednisone in the Management of Pericarditis: A Systematic Review.

This systematic review evaluated the use of oral corticosteroids, primarily prednisone, in adults with acute or recurrent pericarditis.

J Cardiovasc PharmacolOct 1, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Association of HRD Score With Efficacy of Neoadjuvant Short-Course Radiotherapy Plus Sequential Chemoimmunotherapy in pMMR Locally Advanced Rectal Cancer.

This Phase II clinical trial examined the relationship between homologous recombination deficiency (HRD) score and treatment response in 32 patients with mismatch repair-proficient locally advanced rectal cancer…

Cancer Rep (Hoboken)Oct 1, 2026Read summary
Clinical ResearchPhysical Medicine & Rehabilitation

Portable Dynamometry Is Reliable for Measuring Knee and Ankle Strength in Daily Practice: Results From a Systematic Review With Meta-analysis and Evidence Gap Map Using the COSMIN Methodology.

This systematic review and meta-analysis evaluated the reliability and criterion validity of portable dynamometers for measuring knee and ankle muscle strength in both uninjured individuals and those with lower-limb…

J Orthop Sports Phys TherOct 1, 2026Read summary
Clinical ResearchPhysical Medicine & Rehabilitation

Female Soccer Players at High Risk of Injury Maintained Improved Knee Abduction Load 6 Months After Neuromuscular Training Program.

This randomized controlled trial evaluated the effects of a 6-week neuromuscular training (NMT) program on knee abduction moment (KAM) in 150 adolescent female soccer players.

J Orthop Sports Phys TherOct 1, 2026Read summary
Clinical ResearchEndocrinology

A Composite Ovine Forestomach Matrix and Hyaluronic Acid CAMP for the Treatment of Full Thickness Wounds of the Foot in People With Diabetes: A Randomized Controlled Trial.

This randomized controlled trial evaluated the efficacy of a novel composite CAMP, OFM-HA, in treating full thickness diabetic foot ulcers (DFUs) in 143 patients.

Int Wound JOct 1, 2026Read summary
Case ReportInfectious Diseases

Meningococcal meningitis in patients under prolonged eculizumab therapy: Clinical and immunological observations from a case series.

Two patients undergoing prolonged eculizumab therapy developed meningococcal meningitis despite prior vaccination. The clinical presentation included typical symptoms of meningitis, and diagnostic workups confirmed the…

Nefrologia (Engl Ed)Oct 1, 2026Read case
Clinical ResearchObstetrics & GynecologyOpen access

The predictive value of early-pregnancy mean platelet volume for preeclampsia: A meta-analysis.

This meta-analysis assessed whether mean platelet volume (MPV) measured before 20 weeks’ gestation is associated with subsequent preeclampsia.

Acta Obstet Gynecol ScandOct 1, 2026Read summary
Clinical ResearchCardiologyOpen access

Diagnostic Accuracy of Circulating MicroRNAs for Coronary Artery Disease: An Updated Systematic Review and Meta-analysis.

This systematic review and meta-analysis evaluated the diagnostic accuracy of circulating microRNAs (miRNAs) for coronary artery disease (CAD) in 3,879 participants across 24 studies.

J Cardiovasc Transl ResOct 1, 2026Read summary
Clinical ResearchPsychiatry

Irritability in the Mix: An Exploratory Study of the Role of Irritability in Characterising Mood Disorders.

This randomized controlled trial explored the relationship between irritability and mixed states in 82 patients with bipolar disorder over 18 months.

Bipolar DisordOct 1, 2026Read summary
Clinical ResearchPsychiatry

Online stepped care for the treatment of posttraumatic stress disorder: A randomized controlled noninferiority trial.

This randomized controlled non-inferiority trial compared online stepped care with telehealth cognitive processing therapy (CPT) in 84 adults with PTSD or subthreshold PTSD.

Behav Res TherOct 1, 2026Read summary
Clinical ResearchOncology (Medical)

Xiaoaiping Injection Combined with Chemotherapy Versus Chemotherapy Alone for Breast Cancer: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed the efficacy and safety of Xiaoaiping Injection (XAP) combined with chemotherapy versus chemotherapy alone in breast cancer patients.

J Vis ExpOct 1, 2026Read summary
Case ReportAnesthesiology

"Ropi"-Thorax as a Complication of Landmark-Based Paravertebral Pain Catheter Placement: A Case Report.

A 42-year-old female with multiple rib fractures and a hemopneumothorax underwent landmark-guided placement of a paravertebral catheter for analgesia due to obstructed ultrasound visualization.

A A PractOct 1, 2026Read case
Case ReportAnesthesiology

Perioperative Management of an Implanted Spinal Cord Stimulator: A Problem-Based Learning Discussion.

A patient with an implanted spinal cord stimulator (SCS) was scheduled for elective surgery. The case highlighted critical aspects of perioperative management, including the identification of the device, potential…

A A PractOct 1, 2026Read case
Clinical ResearchGastroenterology

Opioid-Sparing Analgesia After Laparoscopic Gastrectomy: Exploratory Clinical Outcomes and Cine-MRI Assessment of Small-Bowel Motility.

This randomized controlled trial evaluated opioid-sparing multimodal analgesia versus conventional opioid analgesia in 130 patients undergoing laparoscopic radical gastrectomy.

J Vis ExpOct 1, 2026Read summary
Case ReportPlastic Surgery

Maxillofacial prosthetic management of oral incompetence following commando surgery and partial maxillectomy: A clinical report.

A patient who underwent commando surgery and partial maxillectomy for squamous cell carcinoma presented with significant facial defects, oral incompetence, and discomfort.

J Indian Prosthodont SocOct 1, 2026Read case

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