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2000 articles

October 202624

Case ReportPathology (Anatomic & Clinical)Open access

Atypical presacral masses in Currarino syndrome: a case series.

The report describes three patients with Currarino syndrome, a congenital condition involving a sacral anomaly, anorectal malformation, and presacral mass.

Childs Nerv SystOct 13, 2026Read case
Clinical ResearchGeriatrics

Feasibility of Online and On-Site Physical Activity Delivery Among Older Adults: Mixed Methods Pilot Randomized Controlled Trial.

This unblinded, site-cluster-randomized mixed methods pilot trial assessed the feasibility of a 26-week Otago physical activity program delivered online or in person to community-dwelling adults aged 60 years or older…

JMIR Form ResOct 13, 2026Read summary
Case ReportAnesthesiology

Successful Kidney Transplantation Under Combined Spinal-Epidural Anesthesia in a Patient With a History of Left Pneumonectomy Due to Bronchiectasis.

A 33-year-old man with end-stage kidney disease from biopsy-proven AA amyloidosis was assessed for preemptive living-donor kidney transplantation.

Am J Case RepOct 13, 2026Read case
Clinical ResearchNeurologyOpen access

Long-Term Quantitative MRI and Quality-of-Life After Endovascular Therapy in Acute Ischemic Stroke - A MR CLEAN-NO IV Substudy.

This long-term substudy of the MR CLEAN-NO IV randomised trial examined quantitative MRI and quality of life three years after acute ischaemic stroke.

Transl Stroke ResOct 13, 2026Read summary
Clinical ResearchNephrology

Haemodiafiltration, haemofiltration and haemodialysis for adults with kidney failure.

This Cochrane systematic review and meta-analysis assessed randomised trials comparing convective dialysis (haemofiltration, haemodiafiltration or acetate-free biofiltration) with diffusive haemodialysis or expanded…

Cochrane Database Syst RevOct 13, 2026Read summary
Clinical ResearchPhysical Medicine & Rehabilitation

Six-month supervised telerehabilitation combining pilates-based therapeutic exercise and self-myofascial release in adults with fibromyalgia: a randomized controlled trial.

This two-arm randomized controlled trial evaluated a six-month supervised home-based telerehabilitation programme in 68 adults with fibromyalgia confirmed by 2016 ACR criteria.

J Rehabil MedOct 13, 2026Read summary
Clinical ResearchInfectious Diseases

Safety and immunogenicity of Thailand Government Pharmaceutical Organization (GPO) produced, COVID-19 vaccine, 10 μg HXP-GPOVac: A Phase III, double-blind, randomized trial in comparison with VAXZEVRIA.

This phase III, double-blind, randomized active-controlled trial compared a single dose of Thailand-produced HXP-GPOVac with VAXZEVRIA in healthy or clinically stable Thai adults who had completed a two-dose COVID-19…

VaccineOct 13, 2026Read summary
Clinical ResearchNeurologyOpen access

Pharmacological and Non-Pharmacological approaches to manage Tension-Type Headache: a Systematic Review.

This systematic review assessed randomized clinical trials of pharmacological and non-pharmacological treatments for episodic or chronic tension-type headache (TTH), examining headache pain and related clinical…

Curr Pain Headache RepOct 13, 2026Read summary
Clinical ResearchPhysical Medicine & RehabilitationOpen access

Factors associated with 1-year health-related quality of life after neck-specific exercise in chronic whiplash-associated disorders: an exploratory secondary analysis of a randomized controlled trial.

This exploratory secondary analysis of a prospective, assessor-blinded, multicentre randomised trial examined factors associated with health-related quality of life (HRQoL) after neck-specific exercise in 140 people…

BMC Musculoskelet DisordOct 13, 2026Read summary
Clinical ResearchPhysical Medicine & Rehabilitation

Refining Home-Based Squat Training: The Role of Hip Adduction in Improving Neuromuscular Control for Clinically Diagnosed Patellofemoral Pain Syndrome.

This randomized controlled trial compared an 8-week home-based squat program with and without hip adduction in 30 participants with clinically diagnosed patellofemoral pain syndrome (PFPS); both groups also performed…

Med Sci MonitOct 13, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Elinzanetant in postmenopausal women with sleep disturbance: results from the randomized, phase II NIRVANA study.

The phase II NIRVANA randomised trial assessed elinzanetant versus placebo in 110 postmenopausal women aged 40–65 years with moderate-to-severe vasomotor symptoms and objectively measured sleep disturbance.

SleepOct 13, 2026Read summary
Clinical ResearchPediatrics

Comparative effects of non-pharmacological intervention categories on cognitive domains in children with autism spectrum disorder: A systematic review and network meta-analysis of randomized controlled trials.

This systematic review and network meta-analysis compared non-pharmacological intervention categories for cognitive outcomes in children with autism spectrum disorder, drawing on randomized controlled trials.

Asian J PsychiatrOct 13, 2026Read summary
Clinical ResearchUrologyOpen access

Opioid-free versus opioid-based anesthesia for robot-assisted radical prostatectomy: a single-center randomized controlled trial.

This single-center randomized controlled trial compared opioid-free anesthesia (dexmedetomidine plus ketamine) with remifentanil-based anesthesia in adult men undergoing robot-assisted radical prostatectomy.

J Robot SurgOct 13, 2026Read summary
Case ReportNeurologyOpen access

Hemi-see-saw nystagmus with superimposed pendular oculopalatal tremor: case report and systematic review.

A 30-year-old man with a pontomedullary arteriovenous malformation presented with pendular hemi-see-saw nystagmus, right one-and-a-half syndrome, gaze-evoked nystagmus, ocular tilt reaction, incomplete Horner syndrome…

J NeurolOct 13, 2026Read case
Clinical ResearchOncology (Medical)Open access

Application of a concise video to improve patient understanding of tumor genomic testing in community and academic practice settings.

This multicenter clinical trial evaluated a 3–4 minute educational video for patients undergoing standard-of-care tumor genomic testing (TGT), across cancer types and academic and community settings.

PLoS OneOct 13, 2026Read summary
Clinical ResearchOphthalmology

USB-powered vs. self-heating warm compresses for meibomian gland dysfunction: A prospective randomized crossover clinical trial.

This prospective randomized crossover trial compared USB-powered and self-heating warm compresses in 15 adults aged 18–40 years with meibomian gland dysfunction and tear break-up time ≤10 s.

PLoS OneOct 13, 2026Read summary
Clinical ResearchInfectious Diseases

The dual burden of disease: Depression among patients with multidrug resistance tuberculosis in low-income and lower- middle-income countries: A systematic review and meta-analysis.

This systematic review and random-effects meta-analysis estimated depression prevalence and examined associated factors among patients with multidrug-resistant tuberculosis (MDR-TB) in low- and lower-middle-income…

PLoS OneOct 13, 2026Read summary
Case ReportGastroenterology

PTCD and Peroral Electronic Cholangioscopy with Holmium Laser Lithotripsy for CBD Stones in a Super-Elderly Patient Post-Billroth II Gastrojejunostomy.

The management of impacted common bile duct stones in patients with prior Billroth II gastrectomy poses unique challenges. Altered gastrointestinal anatomy renders duodenoscope passage and biliary cannulation during…

J Vis ExpOct 13, 2026Read case
Clinical ResearchPulmonology

Machine Learning, Radiomics, and Clinical Models Predicting Checkpoint Inhibitor Pneumonitis in Lung Cancer: A Systematic Review and Meta-analysis.

This systematic review and meta-analysis assessed machine-learning, radiomics, deep-learning, and clinical models for predicting checkpoint inhibitor pneumonitis in people with lung cancer.

J Vis ExpOct 13, 2026Read summary
Clinical ResearchNeurology

Post-Stroke Depression and Determinants in Ethiopia; A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis examined the prevalence and determinants of post-stroke depression (PSD) in Ethiopia, combining findings from eight studies.

Int J Methods Psychiatr ResOct 13, 2026Read summary
Case ReportPhysical Medicine & RehabilitationOpen access

Integrated physical, cognitive and psychological rehabilitation following multiple ACL reconstructions in a professional handball player: a case report.

A 31-year-old professional handball player with two ACL reconstructions, meniscal repairs, a postoperative knee infection, and multiple arthroscopic procedures had persistent knee instability, pain, and psychological…

J Med Case RepOct 13, 2026Read case
Case ReportOphthalmologyOpen access

Extensive recurrent pterygium following photorefractive keratectomy: a case report.

A healthy 39-year-old man developed an extensive recurrent pterygium three months after uneventful photorefractive keratectomy (PRK), having undergone primary pterygium surgery two months before PRK.

BMC OphthalmolOct 13, 2026Read case
Case ReportHematologyOpen access

Myeloid neoplasm with PDGFRA rearrangement presenting in blast-phase with basophilia.

An adult man from Southern Africa presented with progressive fatigue. Blood morphology showed marked basophilia and 21% myeloblasts, with flow cytometry supporting a provisional diagnosis of acute myeloid leukaemia with…

J HematopOct 13, 2026Read case
Case ReportPediatricsOpen access

Successful management of long-term venovenous ECMO for severe PARDS in a child with acute lymphoblastic leukemia.

A 5-year-old boy with low-risk B-cell acute lymphoblastic leukemia developed severe, refractory pediatric acute respiratory distress syndrome during induction therapy, with profound hypoxemia.

J Artif OrgansOct 13, 2026Read case

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