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2000 articles

October 202624

Clinical ResearchOncology (Medical)Open access

Continuous infusion of granulocyte colony-stimulating factor is associated with an advantage in neutrophil recovery in pediatric oncologic disorders.

This randomized controlled trial evaluated the effects of continuous infusion versus injection of granulocyte colony-stimulating factor (G-CSF) on neutrophil recovery in 20 pediatric oncology patients.

Cancer Chemother PharmacolOct 3, 2026Read summary
Clinical ResearchNeurologyOpen access

Brain-Derived Neurotrophic Factor Val66Met Polymorphism and Cognitive Outcome after Stroke: A Systematic Review.

This systematic review examined the association between the BDNF Val66Met polymorphism and cognitive outcomes in 2,494 adults post-stroke.

Transl Stroke ResOct 3, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Prevalence of osteoporosis and low bone mass in men with prostate cancer: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the prevalence of osteoporosis and low bone mass in 91,913 men with prostate cancer (PCa).

Support Care CancerOct 3, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Boesenbergia rotunda extract-based mucoadhesive mouth gargle for chemoradiation-induced oral mucositis: A prospective randomized controlled study.

This randomized controlled trial evaluated the efficacy of a Boesenbergia rotunda extract-based mouth gargle in managing chemoradiation-induced oral mucositis in head and neck cancer patients.

Support Care CancerOct 3, 2026Read summary
Clinical ResearchUrologyOpen access

Robot-assisted versus non-robotic partial nephrectomy for completely endophytic renal tumors: a systematic review and meta-analysis.

This systematic review and meta-analysis compared robot-assisted partial nephrectomy (RAPN) with laparoscopic (LPN) and open partial nephrectomy (OPN) for completely endophytic renal tumors (CERTs) in 896 patients.

J Robot SurgOct 3, 2026Read summary
Clinical ResearchNeurologyOpen access

The Therapeutic Potential of MicroRNAs Delivered By Mesenchymal Stem Cells in Parkinson's Disease, Alzheimer's Disease, and Stroke: A Systematic Review of Preclinical Studies.

This systematic review evaluated 37 preclinical studies on the therapeutic potential of mesenchymal stem cells (MSCs) and their derived microRNAs (miRNAs) in Parkinson's disease, Alzheimer's disease, and stroke.

Mol NeurobiolOct 3, 2026Read summary
Clinical ResearchOncology (Medical)Open access

The impact of intratumor heterogeneity on outcome and resistance to therapy in primary breast cancer: a systematic review.

This systematic review examines the impact of intratumor heterogeneity (ITH) on chemotherapy resistance in primary breast cancer, analyzing 12 studies across various tumor subtypes.

Med OncolOct 3, 2026Read summary
Case ReportEmergency Medicine

Exertional Rhabdomyolysis With Moderate Creatine Kinase Elevation and Marked Transaminase Elevation but Preserved Synthetic Function: A Case Report.

A 43-year-old man presented with fatigue, nausea, and myalgia following a 3000-m run. Laboratory tests revealed moderate creatine kinase (CK) elevation at 2828 U/L alongside significantly elevated transaminases: AST at…

Am J Case RepOct 3, 2026Read case
Clinical ResearchPediatrics

Haemodynamic and neurophysiological assessments for 2-year outcome prediction in neonates with hypoxic-ischaemic encephalopathy treated with therapeutic hypothermia: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the prognostic accuracy of amplitude-integrated electroencephalography (aEEG), cerebral near-infrared spectroscopy (cNIRS), and targeted neonatal echocardiography…

BMJ Paediatr OpenOct 3, 2026Read summary
Clinical ResearchGeneral SurgeryOpen access

Learning curves in robotic and laparoscopic colorectal surgery: a systematic review.

This systematic review evaluated learning curves in laparoscopic and robotic colorectal surgery, analyzing 114 studies with 167 learning-curve analyses.

J Robot SurgOct 3, 2026Read summary
Clinical ResearchGeneral SurgeryOpen access

The learning curve of robotic pancreatoduodenectomy: a systematic review of learning curve assessment methodologies, proficiency thresholds, training pathways and clinical outcomes.

This systematic review evaluated the learning curve of robotic pancreatoduodenectomy (RPD) across 42 studies, focusing on methodologies, proficiency thresholds, and outcomes.

J Robot SurgOct 3, 2026Read summary
Clinical ResearchNephrology

Bone Anabolic Treatment in Patients With Chronic Kidney Disease: A Systematic Review.

This systematic review evaluated the efficacy and safety of anabolic parathyroid hormone (PTH) treatments in patients with chronic kidney disease (CKD) Stages 4-5D.

Basic Clin Pharmacol ToxicolOct 3, 2026Read summary
Clinical ResearchPathology (Anatomic & Clinical)

Concordance of Microbiological and Histopathological Examination of Bone Biopsies in Diagnosing Diabetic Foot Osteomyelitis, a Systematic Review.

This systematic review evaluated the diagnostic concordance of histopathology and microbiology in bone biopsies from 308 adults with diabetic foot osteomyelitis (DFO).

J Foot Ankle ResOct 3, 2026Read summary
Clinical ResearchGeriatrics

Vitamin D Supplementation and Mortality in the Elderly: A Review of a Meta-Analysis of Randomized Controlled Trials Using the REB Method.

This meta-analysis reviewed 25 randomized controlled trials (RCTs) to evaluate the impact of vitamin D supplementation on mortality in individuals aged 75 and older.

Fundam Clin PharmacolOct 3, 2026Read summary
Clinical ResearchNeurology

HD-tACS at 40 Hz improves consciousness and brain connectivity in prolonged disorders of consciousness: a randomized sham-controlled clinical trial.

This randomized, sham-controlled clinical trial evaluated 40 Hz and 4 Hz high-definition transcranial alternating current stimulation (HD-tACS) in 60 patients with prolonged disorders of consciousness.

NeuroimageOct 3, 2026Read summary
Case ReportOncology (Medical)Open access

Complete Regression of 11 Hepatic Metastases in Metastatic Pancreatic Adenosquamous Carcinoma and the Role of GPT in Patient Navigation.

A 65-year-old man with resected pancreatic adenosquamous carcinoma (pT3 pN2, R0) had 11 liver lesions interpreted as metastases on MRI.

Int Med Case Rep JOct 3, 2026Read case
Case ReportInfectious DiseasesOpen access

Blackwater Fever Complicated by Severe Acute Kidney Injury and a Therapeutic Dilemma: A Case Report from Niger.

A 50-year-old woman with persistent Plasmodium falciparum infection and repeated antimalarial treatment, including artesunate, presented with fever, jaundice, and severe acute kidney injury (serum creatinine 1104.1…

Int Med Case Rep JOct 3, 2026Read case
Clinical ResearchPediatrics

Impact of digital health interventions in improving pediatric immunization coverage and timeliness in low- and middle-income countries: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed randomized controlled trials of digital interventions to improve pediatric vaccination outcomes in low- and middle-income countries.

VaccineOct 2, 2026Read summary
Clinical ResearchPediatricsOpen access

Comparison of Molecular Methods With Culture for Identifying Microbial Etiology in Pediatric Empyema Thoracis: A Systematic Review of Diagnostic Test Accuracy.

This systematic review evaluated the diagnostic accuracy of molecular methods versus culture for identifying microbial etiology in pediatric empyema thoracis.

Indian PediatrOct 2, 2026Read summary
Clinical ResearchFamily Medicine

Implementation of Communication Disability Documentation and Accommodations in Primary Care: A Pragmatic Type III Hybrid Implementation-Effectiveness Trial Protocol.

This article describes the protocol for the DECA study, a pragmatic Type III hybrid implementation-effectiveness trial of communication disability (CD) documentation and accommodation processes in primary care.

J Speech Lang Hear ResOct 2, 2026Read summary
Clinical ResearchMedical GeneticsOpen access

Genotype-Phenotype Relationships in Patients Carrying Biallelic FDXR Pathogenic Variants-New Cases and Systematic Review.

Biallelic pathogenic FDXR variations were identified in 2017 as being responsible for sensorial neuropathies. The first reported patients suffered from auditory and optic sensorineural impairments (ANOA, MIM #617717).

Hum MutatOct 2, 2026Read summary
Clinical ResearchOncology (Medical)

Hypofractionated 44 Gy in 20 fractions versus conventional chemoradiation in cervical cancer: 2-year results of the randomized HYPOCx-iRex trial with an exploratory pooled analysis of a single-institute EMBRACE-II cohort.

The randomized HYPOCx-iRex trial compared hypofractionated chemoradiation (44 Gy in 20 fractions) with conventional chemoradiation (45 Gy in 25 fractions) for locally advanced cervical cancer; an exploratory pooled…

BrachytherapyOct 2, 2026Read summary
Clinical ResearchPediatricsOpen access

Postnatal interventions to support newborn survival: updates for the Lives Saved Tool.

This systematic review evaluated postnatal interventions aimed at reducing neonatal mortality, particularly in low- and middle-income countries.

J Glob HealthOct 2, 2026Read summary
Case ReportPediatrics

Primary Surgical Resection of Localized Cervical Kaposiform Hemangioendothelioma in a Neonate: A Potentially Curative Strategy in Selected Patients.

A term female neonate had a 4 × 4 cm cervical mass at birth. Imaging showed a well-circumscribed, highly vascular lesion without infiltration or compression of vital structures; no coagulopathy was detected.

J Pediatr Hematol OncolOct 2, 2026Read case

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