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1566 articles
October 202624
Gestational Choriocarcinoma With Inferior Vena Cava Tumor Thrombus Formation.
A 52-year-old woman presented with recurrent nausea and vomiting, leading to the discovery of elevated serum β-hCG levels and a pelvic mass extending into the inferior vena cava (IVC).
Identification of Variants in Two Families With Congenital Cataract by Whole Exome Sequencing.
Congenital cataract (CC) is an ophthalmic disorder diagnosed at birth or during early infancy, characterized by severe visual impairment and potential blindness.
A Novel De Novo MTM1 Insertion Frameshift Variant Causes X-Linked Myotubular Myopathy in a Chinese Female.
A 24-year-old woman presented with infantile hypotonia and progressive, asymmetric proximal weakness, including facial and ocular involvement.
TMS-Derived Neurophysiological Measures of Corticospinal Excitability, Intracortical Excitability, and Interhemispheric Interactions Associated With Post-Stroke Motor Recovery: A Systematic Review.
This systematic review evaluated the relationship between TMS-derived neurophysiological measures and motor recovery in adults post-stroke, synthesizing data from 16 randomized controlled trials.
Health Economic & Implementation Determinants of Prehospital Stroke Triage Tools: A Systematic Review.
This systematic review evaluated health economic outcomes and implementation determinants of prehospital triage tools for suspected ischaemic stroke patients.
Phase 1 dose escalation and expansion trial of the bispecific CD47 inhibitor and CD40 agonist Fc-fusion protein SL-172154 (SIRPα-Fc-CD40L) in patients with higher-risk myelodysplastic syndrome or acute myeloid leukemia.
This Phase I clinical trial evaluated the safety and efficacy of the bispecific CD47 inhibitor SL-172154 combined with azacitidine (AZA) in patients with higher-risk myelodysplastic syndrome (HR-MDS) or acute myeloid…
Variants in CEP135 Cause Congenital Microcephaly and Primary Ciliary Dyskinesia.
Three children from two families presented with congenital microcephaly and chronic respiratory issues consistent with primary ciliary dyskinesia (PCD). Diagnostic testing revealed autosomal recessive variants in CEP135.
Gut microbiome and healthy ageing: a systematic review of literature.
This systematic review examined the gut microbiome's compositional and functional features associated with healthy ageing, independent of age-related diseases.
Screening Strategies for Silent Myocardial Ischemia in Individuals With Diabetes Without Known Coronary Artery Disease: Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the effectiveness of routine screening for silent myocardial ischemia in asymptomatic adults with diabetes and no known coronary artery disease.
Tumor Profile, Clinical Features, and Outcomes in Individuals With Constitutional Trisomy 8: A Systematic Review of Case Reports and Case Series.
Constitutional trisomy 8 mosaicism (CT8M) is a rare chromosomal disorder with poorly characterized cancer risk. This systematic review aimed at summarizing reported cases of malignancy and associated clinical outcomes…
Mosaicism for Cohen-Gibson Syndrome in a Female Individual With Overgrowth and Neurodevelopmental Delay.
A 12-year-old girl presented with tall stature, dysmorphic features, developmental delay, and congenital anomalies. Genetic evaluation revealed a likely pathogenic mosaic variant in the EED gene, with varying allele…
Iran's Escherichia coli AMR Landscape (2010-2025): A One Health Systematic Review and Meta-Analysis.
This systematic review and meta-analysis examined the prevalence of antimicrobial resistance (AMR) in Escherichia coli across humans, animals, foods, and the environment in Iran from 2010 to 2025.
A Case of Primary Intramedullary Infantile Fibrosarcoma With an RBPMS::NTRK3 Fusion and Response to Larotrectinib.
A 4-week-old infant presented with rapidly progressive cervical myelopathy due to primary intramedullary infantile fibrosarcoma.
Evolving Fetal Biometry in Fetal Intrahepatic Portosystemic Shunt With Late-Onset Preeclampsia and Focal Umbilical Cord Hypercoiling: A Case Report.
A pregnancy was evaluated at 26 + 3 weeks for suspected severe early-onset fetal growth restriction, with fetal weight below the 1st percentile. Imaging revealed a fetal intrahepatic portosystemic shunt.
Effect of Skin-To-Skin Contact During Caesarean Section on Pain and Stress in Newborns: A Randomized Controlled Trial.
This randomized controlled trial evaluated the impact of skin-to-skin contact during caesarean sections on neonatal pain and stress during the first intramuscular injection.
Disseminated Bartonella or Post-Transplant Lymphoproliferative Disease in Pediatric Transplant Patients: A Diagnostic Challenge.
A pediatric kidney transplant patient presented with fever, lymphadenopathy, nausea, vomiting, and abdominal pain. An extensive workup for post-transplant lymphoproliferative disease (PTLD) was initiated, including PET…
Intraprocedural Hemodynamics During Concomitant Rheocarna Therapy and Maintenance Hemodialysis: Effects of Dialyzer Membrane Type and Circuit Sequence.
Two patients with chronic limb-threatening ischemia (CLTI) undergoing maintenance hemodialysis received concomitant Rheocarna therapy.
Balloon Enteroscopy-Assisted ERCP and EUS-Guided Biliary Drainage for Malignant Biliary Obstruction in Patients With Surgically Altered Anatomy: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed balloon enteroscopy-assisted ERCP (BEA-ERCP) versus EUS-guided biliary drainage (EUS-BD) for malignant biliary obstruction in patients with surgically altered anatomy.
Short-Term Effects of a Self-Monitoring-Based Intervention on Prolonged Sedentary Behavior in Older Adults With Cardiovascular Conditions: An Exploratory Secondary Analysis of a Randomized Controlled Trial.
This exploratory secondary analysis of a randomized controlled trial examined the impact of an accelerometer-guided self-monitoring intervention on prolonged sedentary behavior in older adults with cardiovascular…
Histological Analysis Shows That a Moisturizer Formulated for Dermatoporosis Increases Elastin Content and Improves Skin Elasticity.
This multicenter clinical trial evaluated the effects of a novel moisturizer (GC cream) on skin biomarkers in individuals aged 40 to 60 with dermatoporosis.
The impact of unilateral endometriomas on ovarian response to stimulation: a systematic review and meta-analysis.
This systematic review and meta-analysis examined the impact of unoperated unilateral endometriomas on ovarian response during stimulation cycles in women with endometriosis.
A double-blind multi-centre randomised placebo-controlled trial of doxycycline in women with recurrent miscarriage and chronic endometritis defined by CD138 positive stromal cells.
This multicenter, double-blind, randomized controlled trial evaluated the effect of preconceptual doxycycline on live birth rates in women with recurrent miscarriage and chronic endometritis defined by CD138 positive…
Health Communication and Stepped Reminders Interventions for Lung Cancer Screening: A Randomized Clinical Trial.
This randomized clinical trial evaluated two patient-centered interventions aimed at increasing adherence to annual lung cancer screening among patients with normal findings.
Autonomous Oxygen Titration for Maintaining Normoxemia in Acutely Ill Adults: The SAVE-O2 AI Randomized Clinical Trial.
The SAVE-O2 AI randomized clinical trial evaluated the effectiveness of autonomous oxygen titration in maintaining normoxemia in acutely ill adults receiving supplemental oxygen.
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