Trending archive
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1566 articles
October 202610
Oral peri-implant tissue as a neoplastic bed: a systematic review of clinicopathology, pathogenesis, and survival outcomes.
This systematic review assessed the clinicopathology, associated factors, and survival outcomes of histologically confirmed neoplasms adjacent to dental implants.
Envenomation by a Razi's viper, Macrovipera razii (Serpentes: Viperidae) in Iran: A neglected public health threat, report of two cases, and clinical implications.
Two men in Iran developed severe local injury after bites from Macrovipera razii. A 36-year-old man bitten on a finger received six vials of polyvalent antivenom but developed progressive necrosis, leaving permanent…
Positive emotions and credibility: Understanding how a community-engaged online campaign featuring clinician testimonials improved rural vaccine promotion.
This four-arm randomized survey experiment tested the community-engaged Communities Confronting COVID-19 campaign among 1,364 rural U.S. residents.
Davos@home: Integrating objective home monitoring into eHealth self-management support after alpine altitude climate treatment for severe asthma.
This 12-month pragmatic randomised trial assessed whether objective home monitoring adds benefit to eHealth self-management after Alpine Altitude Climate Treatment (AACT) in adults with severe asthma.
Systematic Review: Inclusion of Patients With Difficult-to-Treat Inflammatory Bowel Disease in Randomized Controlled Trials of Advanced Therapies.
This systematic review examined how patients with difficult-to-treat inflammatory bowel disease (DTT-IBD) were represented in randomized controlled trials of advanced therapies for ulcerative colitis and Crohn’s…
Exceptional and Durable Response to Selpercatinib in a Patient with Apparently RET -Negative, HRAS -, and NF1 -Mutated Metastatic Medullary Thyroid Carcinoma.
A 50-year-old woman presented with rapidly progressive medullary thyroid carcinoma (Ki-67 30%) and extensive liver and bone metastases.
Clinical trial: The Effect on Intragastric pH and Pharmacokinetics of the PCAB Linaprazan Glurate in Healthy Subjects After Repeat-Dose Administration for up to 14 Days.
This open, randomised, parallel-group Phase 1 trial assessed intragastric pH and pharmacokinetics after single and repeated linaprazan glurate (LG) dosing in 73 healthy subjects.
Effects of sprint interval training on markers of metabolic health: A three-level meta-analysis of randomised controlled trials.
This systematic review and three-level meta-analysis examined randomised controlled trials comparing sprint interval training (SIT) with no-exercise control or moderate-intensity continuous training (MICT) for metabolic…
Updated Meta-Analysis of Left Atrial Appendage Closure Versus Oral Anticoagulation to Prevent Stroke in Atrial Fibrillation.
This systematic review and meta-analysis pooled six randomized controlled trials comparing percutaneous left atrial appendage closure (LAAC) with oral anticoagulation in 7028 patients with nonvalvular atrial…
The predictive value of early-pregnancy mean platelet volume for preeclampsia: A meta-analysis.
This meta-analysis assessed whether mean platelet volume (MPV) measured before 20 weeks’ gestation is associated with subsequent preeclampsia.
September 202614
Continuous Intravenous Acyclovir as Outpatient Parenteral Antimicrobial Therapy for HSV and VZV Neurological Infections: A Case Series With Pharmacokinetic and Cost Evaluation, and Review of Literature.
This case series involved eight patients with neurological infections caused by HSV or VZV who transitioned to continuous intravenous acyclovir via an outpatient parenteral antimicrobial therapy (OPAT) program after…
Impact of EBV status and histology on patient outcomes with nivolumab-AVD vs BV-AVD in advanced classic Hodgkin lymphoma (S1826).
This phase 3 randomized controlled trial evaluated the impact of EBV status and histology on outcomes in patients with advanced classic Hodgkin lymphoma treated with nivolumab-AVD (N-AVD) versus brentuximab vedotin-AVD…
A phase 1/1b study of the all-oral regimen CC-486 and venetoclax in acute myeloid leukemia.
This phase 1/1b study evaluated the all-oral regimen of CC-486 and venetoclax in patients with relapsed, refractory, and newly diagnosed acute myeloid leukemia (AML).
A phase 1b/2 study of ceralasertib, a selective inhibitor of ATR, in patients with relapsed or refractory MDS and CMML.
This phase 1b/2 study evaluated ceralasertib, an ATR inhibitor, in 44 adults with relapsed or refractory MDS and CMML. The overall response rate was 29.5%, with a median progression-free survival of 4.8 months and…
'Once Bitten': A Case of Tetanus Following Snakebite in Australia.
A 58-year-old woman in Victoria, Australia, presented after a suspected Tiger snake bite. She was not current with her tetanus vaccination and did not receive a booster.
Clinical, economic, and quality-of-life outcomes of brexucabtagene autoleucel for the treatment of relapsed/refractory mantle cell lymphoma and B-cell acute lymphoblastic leukemia: A systematic literature review and meta-analysis.
This systematic literature review and meta-analysis evaluated the clinical, healthcare resource use, and quality-of-life outcomes of brexucabtagene autoleucel in adults with relapsed/refractory mantle cell lymphoma…
Endoscopic Ultrasound-Guided Hepaticogastrostomy With Plastic Stent Versus Metallic Stent for Malignant Biliary Obstruction: A Meta-Analysis.
This meta-analysis evaluated the efficacy and safety of plastic versus metal stents in endoscopic ultrasound-guided hepaticogastrostomy (EUS-HGS) for malignant biliary obstruction.
Repetitive Transcranial Magnetic Stimulation Combined With Median Nerve Electrical Stimulation for Severe Traumatic Brain Injury.
This randomized controlled trial investigated the effects of repetitive transcranial magnetic stimulation (rTMS) combined with median nerve electrical stimulation (MNS) in 86 patients with severe traumatic brain injury…
Sex-Discordant Monochorionic Dizygotic Twins After Double Blastocyst Transfer: Blood Chimerism Demonstrated by Multimodal Genetic Testing.
A 38-year-old woman conceived through intracytoplasmic sperm injection and double blastocyst transfer, leading to monochorionic diamniotic twins. At 21 weeks, discordant external genitalia were noted.
Rituximab as Rescue or Add-On Therapy for Relapsing or Refractory Lupus Nephritis: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the efficacy of rituximab (RTX) as rescue or add-on therapy for relapsing or refractory lupus nephritis in 445 patients.
Metastasis of Invasive Ductal Carcinoma of the Breast to the Uterine Cervix 30 Years Post-Mastectomy: A Case Report.
A 69-year-old woman, 30 years post-mastectomy for invasive ductal carcinoma, presented with abnormal cervical cytology. Imaging revealed a 38-mm cervical mass, leading to a modified radical hysterectomy.
Reducing Peripheral Intravenous Catheter Use in Adult Acute Care: A Systematic Review.
This systematic review evaluated interventions aimed at reducing peripheral intravenous catheter (PIVC) use in adult acute care settings.
Effectiveness, Mediators and Moderators of Remote Live vs. Pre-Recorded Physical Exercise Training for Chronic Low Back Pain.
This randomized controlled trial evaluated the effectiveness of live interactive versus pre-recorded remote exercise training for chronic low back pain (CLBP) in 94 patients.
First systematic mapping of non-target [68Ga]Ga-DOTANOC uptake across anatomical sites and etiologies.
This systematic review analyzed 76 studies involving 542 patients to map non-target [68Ga]Ga-DOTANOC uptake across various anatomical sites and etiologies.
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