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1687 articles

October 202624

Clinical ResearchGastroenterology

Follow-up colonoscopy after abnormal stool-based colorectal cancer screening: a systematic review of completion, timeliness and implementation strategies.

This systematic review examined the completion rates and timeliness of diagnostic colonoscopy following abnormal stool-based colorectal cancer screenings in adults.

BMJ OpenOct 5, 2026Read summary
Clinical ResearchMedical Genetics

PHOENIX: a study protocol for a pilot randomised controlled trial of pre-emptive pharmacogenomic panel testing in acute care settings with health economic evaluations.

The PHOENIX trial is a pilot randomized controlled trial assessing the impact of pre-emptive pharmacogenomic panel testing on adverse drug reactions (ADRs) and treatment failures in acute care settings.

BMJ OpenOct 5, 2026Read summary
Clinical ResearchHematology

Efficacy and safety of erythrocytapheresis in chronic mountain sickness: a randomised controlled trial protocol (ESCAPE-CMS).

This randomized controlled trial protocol investigates the efficacy and safety of erythrocytapheresis in patients with chronic mountain sickness (CMS), a condition affecting over 4 million individuals at high altitudes.

BMJ OpenOct 5, 2026Read summary
Clinical ResearchCardiology

Home-based neuro-cardiac rehabilitation in congenital heart disease: the QUALINEURO-REHAB trial study protocol.

The QUALINEURO-REHAB trial is a multicenter, two-arm randomized controlled trial assessing a home-based neuro-cardiac rehabilitation program in youth aged 8-25 with complex congenital heart disease (CHD).

BMJ OpenOct 5, 2026Read summary
Clinical ResearchNeurology

Machine Learning and Deep Learning for the Diagnosis of Cervical Degenerative Diseases: Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated traditional machine learning (TML) and deep learning (DL) approaches for diagnosing cervical degenerative diseases, analyzing data from 30 studies involving 25,301…

J Med Internet ResOct 5, 2026Read summary
Clinical ResearchPsychiatry

Efficacy of a Prescription-Based Mobile Digital Therapeutic as an Adjunct to Pharmacotherapy for the Acute Phase of Panic Disorder: Multicenter Randomized Controlled Trial.

This multicenter randomized controlled trial evaluated the efficacy of a prescription-based mobile digital therapeutic (DTx) as an adjunct to pharmacotherapy in 66 patients with acute-phase panic disorder.

J Med Internet ResOct 5, 2026Read summary
Clinical ResearchPediatrics

Serum ferritin in children with Attention Deficit Hyperactivity Disorder (ADHD): A systematic review and meta-analysis.

This systematic review and meta-analysis examined serum ferritin levels in children with Attention Deficit Hyperactivity Disorder (ADHD) compared to healthy controls.

PLoS OneOct 5, 2026Read summary
Clinical ResearchInfectious Diseases

Temporal proximity to counseling is associated with longitudinal bedaquiline and antiretroviral therapy adherence in multidrug-resistant tuberculosis and HIV treatment.

This randomized controlled trial examined the relationship between counseling session timing and medication adherence in 76 participants receiving treatment for multidrug-resistant tuberculosis (MDR-TB) and HIV in South…

PLoS OneOct 5, 2026Read summary
Case ReportOtolaryngology (ENT)

Treatment of External Auditory Canal Hemangioma by Surgical Excision and Flap Reconstruction: 2 Case Reports.

Two cases of external auditory canal (EAC) hemangiomas are reported. The first case involved a 68-year-old man with a sensation of fullness in the left ear, while the second case involved a 62-year-old woman with…

Am J Case RepOct 5, 2026Read case
Clinical ResearchPsychiatry

A Problem-Solving Therapy With Apple Watch Support for College Students With Alcohol Use Disorder Symptoms: Pilot Randomized Controlled Trial.

This pilot randomized controlled trial evaluated the feasibility and preliminary effectiveness of a problem-solving therapy supported by Apple Watch (PST-APPLE) for college students with alcohol use disorder (AUD)…

JMIR Form ResOct 5, 2026Read summary
Clinical ResearchCardiologyOpen access

Effects of Benzodiazepines on Heart Failure Outcomes and Adverse Events: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated the impact of benzodiazepines (BZDs) on heart failure (HF) outcomes in high-risk populations.

Cardiovasc ToxicolOct 5, 2026Read summary
Clinical ResearchOrthopedic SurgeryOpen access

Morphometric findings of the subaxial cervical spine among different geographic regions and the implications for cervical pedicle screw placement: a systematic review and meta-analysis.

This systematic review and meta-analysis examined cervical pedicle dimensions and insertion angles across diverse populations, analyzing data from 4014 patients across 18 countries.

Neurosurg RevOct 5, 2026Read summary
Clinical ResearchUrologyOpen access

Lymphocele After Radical Prostatectomy: A Systematic Review of Risk Factors and Quantitative Synthesis Preventive Strategies.

This systematic review evaluated risk factors and preventive strategies for lymphocele formation after radical prostatectomy with pelvic lymph node dissection.

World J UrolOct 5, 2026Read summary
Case ReportNephrologyOpen access

Nephrotic range proteinuria and rapid progression to end-stage kidney disease in seronegative pauci-immune necrotizing glomerulonephritis masked by cutaneous lesions: a case-based review.

A 22-year-old woman with a history of recurrent cutaneous lesions was hospitalized due to exacerbation of her skin condition. Laboratory tests revealed nephrotic-range proteinuria and reduced eGFR.

Rheumatol IntOct 5, 2026Read case
Clinical ResearchEndocrinologyOpen access

Cardiovascular Morbidity and Mortality in Chronic Hypoparathyroidism: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated the cardiovascular risks associated with chronic hypoparathyroidism (HypoPT) in adults.

Calcif Tissue IntOct 5, 2026Read summary
Clinical ResearchNeurologyOpen access

Electroacupuncture Targeting the NLRP3 Inflammasome in Senescence‑associated Cognitive Impairment: Mechanistic Synthesis and Meta‑analysis of Clinical Randomized Controlled Trials.

This meta-analysis reviewed nine randomized controlled trials involving 614 participants to evaluate the effects of electroacupuncture on senescence-associated cognitive impairment (SACI).

Neurochem ResOct 5, 2026Read summary
Clinical ResearchEndocrinology

Effects of rosehip (Rosa canina) supplementation on orthostatic intolerance symptoms in patients with type 2 diabetes: a randomized double-blind placebo-controlled clinical trial.

This randomized double-blind placebo-controlled trial investigated the effects of rosehip fruit extract on orthostatic intolerance symptoms in 60 adults with type 2 diabetes and orthostatic hypotension.

DaruOct 5, 2026Read summary
Clinical ResearchPreventive Medicine / Public Health

Fluid balance during hot-dry and warm-humid heat stress while adhering to occupational hydration recommendations.

This randomized controlled trial assessed fluid balance in 20 healthy adults during moderate-intensity work in hot-dry (HD) and warm-humid (WH) environments while following NIOSH hydration recommendations.

Ann Work Expo HealthOct 5, 2026Read summary
Clinical ResearchOncology (Medical)

A study on the intervention effect of a structured grief counseling program on grief responses in family caregivers of patients with advanced cancer.

This randomized controlled trial evaluated the impact of structured grief counseling on grief responses in family caregivers of advanced cancer patients.

Palliat Support CareOct 5, 2026Read summary
Case ReportNephrology

When Infection Mimics Vasculitis: Hydralazine-Induced ANCA-Associated Crescentic Glomerulonephritis in the Setting of Active Infective Endocarditis.

A 58-year-old man with a history of bicuspid aortic valve presented with fatigue, anemia, and acute kidney injury. He was diagnosed with subacute infective endocarditis after blood cultures grew Streptococcus mutans.

Am J Case RepOct 5, 2026Read case
Case ReportNeurologyOpen access

Familial hypomagnesemia with secondary hypocalcemia: a novel TRPM6 mutation associated with treatment-resistant migraine in a North African family.

An 18-year-old woman from a consanguineous Moroccan family presented with lifelong hypomagnesemia and a severe migraine attack accompanied by paresthesias and muscle cramps.

Neurol SciOct 5, 2026Read case
Clinical ResearchNeurologyOpen access

Systemic inflammatory response syndrome and adverse outcomes in acute intracerebral hemorrhage: a meta-analysis.

This meta-analysis evaluated the prognostic significance of systemic inflammatory response syndrome (SIRS) in 6,976 patients with acute intracerebral hemorrhage (ICH).

Neurol SciOct 5, 2026Read summary
Clinical ResearchMedical GeneticsOpen access

A nationwide prospective randomized trial for diagnosing developmental disorders demonstrates genome sequencing outperforms standard of care.

This nationwide prospective randomized trial evaluated the diagnostic efficacy of genome sequencing (GS) compared to standard of care (SoC) in 567 individuals with unexplained developmental disorders (DD).

Genome MedOct 5, 2026Read summary
Case ReportEmergency Medicine

Ultrasound-Guided Disposition: Submersion Injury.

A 25-year-old male sustained an acute submersion injury due to water aspiration during snorkel training for U.S. Navy Search and Rescue Swimmer training.

J Spec Oper MedOct 5, 2026Read case

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