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1687 articles

October 202624

Clinical ResearchGastroenterology

Efficacy of Bifidobacterium animalis subsp. lactate BL-99 in relieving functional constipation: a randomized placebo-controlled clinical trial.

This randomized, double-blind, placebo-controlled trial evaluated the efficacy of Bifidobacterium animalis subsp. lactis BL-99 in 41 patients with functional constipation over 6 weeks.

Food FunctOct 5, 2026Read summary
Clinical ResearchUrology

Caudal versus penile block and urethrocutaneous fistula formation following hypospadias repair in children <2 years: a multicenter randomized clinical trial.

This multicenter randomized controlled trial evaluated the incidence of urethrocutaneous fistula (UCF) formation in children under 2 years undergoing hypospadias repair with either caudal or penile block.

Reg Anesth Pain MedOct 5, 2026Read summary
Clinical ResearchCardiology

Flavonoid-rich foods and vascular functions in healthy adults: a systematic review and meta-analysis of randomized controlled trials.

This systematic review and meta-analysis evaluated the effects of flavonoid-rich foods on vascular function in 561 healthy adults across 11 randomized controlled trials.

Food FunctOct 5, 2026Read summary
Clinical ResearchEndocrinology

Chestnut flour-enriched bread reduces postprandial glycaemic response in healthy adults: a randomised, controlled crossover study.

This randomized controlled crossover study evaluated the impact of chestnut flour-enriched bread on postprandial glycaemic responses in fourteen healthy adults.

Food FunctOct 5, 2026Read summary
Clinical ResearchEmergency Medicine

Comparative Ultrasound Assessment of Standard and Wire-Core Airway Bougie Introducers in a Cadaver Model.

This randomized controlled trial evaluated the accuracy of point-of-care ultrasound (POCUS) in identifying standard bougie (SB) versus wire-core bougie (WCB) placements in cadaver models.

J Spec Oper MedOct 5, 2026Read summary
Clinical ResearchInfectious Diseases

Geographical and temporal patterns of cutaneous leishmaniasis in Pakistan: insight from a decade of epidemiology.

This systematic review examined the geographical distribution and epidemiological trends of cutaneous leishmaniasis (CL) in Pakistan from 2014 to 2024.

Trans R Soc Trop Med HygOct 5, 2026Read summary
Case ReportCardiology

Cardiac arrest revealing an occult interventricular septal hydatid cyst in a child.

An 11-year-old girl experienced sudden cardiac arrest during a biopsy of a dorsal hydatid cyst. After resuscitation, echocardiography revealed a 5.3 × 4.6 cm cyst in the interventricular septum, with CT showing liver…

Trans R Soc Trop Med HygOct 5, 2026Read case
Clinical ResearchAnesthesiology

Clinical utility of randomized controlled trials of regional anesthesia for lower-extremity surgery: a systematic review.

This systematic review evaluated the clinical utility and transparency of randomized controlled trials (RCTs) on regional anesthesia (RA) for lower-extremity surgeries.

Reg Anesth Pain MedOct 5, 2026Read summary
Clinical ResearchAnesthesiology

Assessing the completeness of safety reporting in clinical trials of regional anesthesia interventions: a registry-publication comparison systematic review.

This systematic review evaluated the completeness of adverse event (AE) reporting in interventional regional anesthesia trials registered on ClinicalTrials.gov and their corresponding publications.

Reg Anesth Pain MedOct 5, 2026Read summary
Clinical ResearchPlastic Surgery

Feeding following cleft palate surgery: a prospective randomized clinical trial comparing suprazygomatic maxillary nerve block and greater palatine nerve block.

This randomized controlled trial evaluated the effectiveness of suprazygomatic maxillary nerve blocks (SZMNB) versus greater palatine nerve blocks (GPNB) in children aged 1-10 undergoing cleft palate surgery.

Reg Anesth Pain MedOct 5, 2026Read summary
Clinical ResearchNeurology

Objective, long-term mobility data in patients with chronic pain after lumbar spine surgery treated with spinal cord stimulation-a prospective, multicenter trial.

This multicenter clinical trial evaluated the long-term effects of spinal cord stimulation (SCS) on mobility in 50 patients with chronic pain following lumbar spine surgery.

Reg Anesth Pain MedOct 5, 2026Read summary
Clinical ResearchAnesthesiology

Impact of opioid-free general anesthesia with locoregional blocks during breast cancer surgery on systemic inflammatory response: results from a randomized controlled trial.

This randomized controlled trial evaluated the effects of opioid-free general anesthesia with locoregional blocks (OfGA) versus traditional opioid-based general anesthesia (GA) on postoperative inflammation in breast…

Reg Anesth Pain MedOct 5, 2026Read summary
Clinical ResearchCardiologyOpen access

Percutaneous coronary intervention using sirolimus-eluting balloons in patients at high bleeding risk: the SELUTION DeNovo HBR substudy.

The SELUTION DeNovo trial, a randomized controlled trial, evaluated sirolimus-eluting balloons (SEBs) versus drug-eluting stents (DES) in 522 high bleeding risk (HBR) patients.

EuroInterventionOct 5, 2026Read summary
Clinical ResearchCardiologyOpen access

Complexity of coronary artery disease in infarct-related cardiogenic shock and multivessel disease: a substudy of the DanGer Shock trial.

This study, a secondary analysis of the DanGer Shock trial, evaluated the prognostic significance of baseline and residual SYNTAX scores in 256 patients with multivessel disease and infarct-related cardiogenic shock.

EuroInterventionOct 5, 2026Read summary
Clinical ResearchCardiologyOpen access

Standardised versus visual assessment of device success after percutaneous coronary intervention.

This randomized controlled trial evaluated the alignment of operator-reported device success with standardized definitions using quantitative coronary angiography (QCA) in 1,548 patients undergoing percutaneous coronary…

EuroInterventionOct 5, 2026Read summary
Clinical ResearchGeneral Surgery

Restorative resection in robot-assisted versus laparoscopic total mesorectal excision: systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the outcomes of robot-assisted total mesorectal excision (R-TME) versus laparoscopic total mesorectal excision (L-TME) in rectal cancer surgery, involving 7133 patients…

Br J SurgOct 5, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Integration of Virtual and Augmented Reality Into Obstetric Nursing and Midwifery Education: Systematic Review.

This systematic review evaluated the use of virtual reality (VR) and augmented reality (AR) in obstetric nursing and midwifery education, analyzing four studies with 634 participants.

JMIR NursOct 5, 2026Read summary
Case ReportEndocrinology

Off-label palopegteriparatide for severe pediatric postsurgical hypocalcemia.

A 14-year-old boy with Graves’ disease developed profound hypocalcemia after total thyroidectomy, with serum calcium 5.9 mg/dL, ionized calcium 0.83 mmol/L, and undetectable parathyroid hormone.

Eur J EndocrinolOct 5, 2026Read case
Clinical ResearchGastroenterology

SYSTEMATIC REVIEW AND BRAZILIAN EXPERT CONSENSUS ON THE USE OF BIOSIMILARS IN INFLAMMATORY BOWEL DISEASE: BRAZILIAN ORGANIZATION FOR CROHN'S AND COLITIS.

This systematic review and Brazilian expert consensus assessed biosimilar use in inflammatory bowel disease (IBD), addressing clinical, therapeutic, and economic questions.

Arq GastroenterolOct 5, 2026Read summary
Clinical ResearchOphthalmology

Microperimetry Sensitivity Changes at the Functional Transition Zone and at the EZ Margins in X-Linked Retinitis Pigmentosa Treated With Gene Therapy.

This post-hoc analysis of the randomized Skyline trial examined how photoreceptor ellipsoid-zone (EZ) structure related to microperimetry sensitivity in eyes with X-linked retinitis pigmentosa treated with gene therapy.

Transl Vis Sci TechnolOct 5, 2026Read summary
Case ReportObstetrics & GynecologyOpen access

Fetal hemothorax due to intrapleural rupture of a small anterior thoracic lymphatic malformation: a case report.

A pregnant woman was referred at 26 weeks after bloody fetal pleural fluid was obtained by thoracentesis. Ultrasound showed right pleural effusion and a small, avascular heterogeneous area in the anterior chest wall…

J Med Case RepOct 5, 2026Read case
Clinical ResearchRheumatologyOpen access

Drug treatments for fibromyalgia: systematic review and network meta-analysis of randomised trials.

This systematic review and network meta-analysis compared drug treatments for fibromyalgia in adults, including evidence from 151 randomised trials involving 32 592 participants.

BMJ MedOct 5, 2026Read summary
Case ReportAllergy & ImmunologyOpen access

Adult-Onset Henoch-Schönlein Purpura Triggered by Isotretinoin with Persistent Polyarthritis and Isolated Cutaneous-Gastrointestinal Involvement: A Case Report.

A 30-year-old woman developed palpable purpura, abdominal pain, and symmetric polyarthritis three weeks after starting isotretinoin.

Int Med Case Rep JOct 5, 2026Read case
Case ReportAnesthesiologyOpen access

Remimazolam ED95 for Preoperative Sedation in Children with Obstructive Sleep Apnea, with Obesity or a Reference-Range BMI: A Biased-Coin Dose-Finding Study.

Obesity may alter total-body-weight dosing of remimazolam, whereas obstructive sleep apnea narrows the respiratory safety margin.

Drug Des Devel TherOct 5, 2026Read case

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